Immunotherapy News and Research

Latest Immunotherapy News and Research

Development of SARS-CoV-2 antibody escape variants in an immunocompromised individual

A new study published in mBio discusses the microevolution of SARS-CoV-2.

31 Aug 2021

FDA grants seven years of marketing exclusivity for Octapharma’s Octagam 10%

Octapharma USA today announced the U.S. Food and Drug Administration (FDA) Office of Orphan Products Development (OOPD) has awarded seven years of marketing exclusivity for Octagam® 10% [Immune Globulin Intravenous (Human)], the first and only intravenous immunoglobulin (IVIg) to be indicated for the treatment of adult dermatomyositis (DM).

31 Aug 2021

DNMT2/TRDMT1 gene knockout may potentiate adverse effects related to drug-induced senescence

Aging-US published "The lack of functional DNMT2/TRDMT1 gene modulates cancer cell responses during drug-induced senescence" which reported that cellular senescence may be a side effect of chemotherapy and other anti-cancer treatments that may promote inflammation and paracrine secondary senescence in healthy tissues.

31 Aug 2021

Adding berzosertib to standard treatment for metastatic urothelial cancer does not extend patient survival

A Phase 2 trial led by City of Hope, a world-renowned research and treatment center for cancer and diabetes, suggests that adding the novel ataxia telangiectasia and Rad3-related (ATR) inhibitor drug berzosertib to standard-of-care chemotherapy for patients with metastatic urothelial cancer does not extend progression-free survival.

27 Aug 2021

MSK researchers identify potential biomarker of response to checkpoint immunotherapy

In recent years, immune-based treatments for cancer have buoyed the hopes of doctors and patients alike. Drugs called immune checkpoint inhibitors have provided lifesaving benefits to a growing list of people with several types of cancer, including melanoma, lung cancer, bladder cancer, and many more.

25 Aug 2021

Researchers identify mechanism for formation of rare colorectal cancer subtype

Researchers from Rutgers Cancer Institute of New Jersey, the state's only National Cancer Institute-designated Comprehensive Cancer Center, recently discovered a mechanism to explain what drives the formation of mucinous colorectal adenocarcinoma (MAC), a rare subtype of colorectal cancer (CRC), and has also identified the genes responsible for the regulation of this mechanism.

25 Aug 2021

New artificial blood vessel platform for predicting organ transplant rejection

Organ transplantation involves the transplantation of organs from donors as a means to treat disease or injury, but there is a shortage of organs available for donation compared to the demand for organ transplantation.

25 Aug 2021

Study finds a new line of drugs to stimulate myelin repair in multiple sclerosis

In the nearly 1 million Americans living with multiple sclerosis, the fatty substance that insulates the nerves of the central nervous system—called myelin—is damaged.

24 Aug 2021

Intestinal microorganisms help regulate anti-tumor immune responses to radiation therapy, study finds

Cedars-Sinai Cancer researchers have discovered that intestinal microorganisms help regulate anti-tumor immune responses to radiation treatments, and that fungi and bacteria have opposing effects on those responses.

24 Aug 2021

UCLA scientists receive $1 million translational award to advance CAR T cell therapy for rare melanomas

Scientists Dr. Cristina Puig-Saus and Dr. Daniel Shin from the UCLA Jonsson Comprehensive Cancer Center have received a $1 million Translational Research Award from the U.S. Department of Defense Melanoma Research Program to help advance the use of chimeric antigen receptor, or CAR, T cell therapy as a treatment for people with acral, mucosal and uveal melanomas.

24 Aug 2021

ICL fluorescent label homogenously penetrates the glioblastoma brain tumors

Fluorescent indocarbocyanine lipid (ICL) shows much better distribution within glioblastoma brain tumors compared to fluorescent phospholipids, according to a study published in ACS Nano.

23 Aug 2021

New PULSAR radiation-therapy strategy achieves better tumor control

Artificial intelligence, along with a $71-million expansion of Radiation Oncology services, is allowing UT Southwestern Medical Center cancer physicians to pioneer a new PULSAR radiation-therapy strategy that improves tumor control compared with traditional daily therapy.

From Elekta 20 Aug 2021

New prediction model can identify NSCLC patients who are not likely to respond to immunotherapy

Immunotherapy agents that inhibit the molecules PD1, PD-L1 or CTLA-4 have become widely used in clinical practice to treat non-small cell lung cancer, or NSCLC.

20 Aug 2021

Researchers create a novel strategy for developing an effective TB vaccine

Innovators at Purdue University and Houston Methodist Research Institute have created a novel strategy for developing an effective vaccine for a widespread form of tuberculosis.

20 Aug 2021

Study in dogs may lead to better understanding of how gliomas affect the immune system

A new study reveals that high-grade gliomas, or brain tumors, in dogs contained more immune cells associated with suppressing immune response than low-grade gliomas.

20 Aug 2021

Prior treatment may impact efficacy of ACT-TIL in patients with metastatic melanoma

Patients with metastatic melanoma that had relapsed on anti-PD-1 therapies or BRAF/MEK inhibitors did not respond as well to an investigational therapy that involves the adoptive cell transfer of tumor-infiltrating lymphocytes (ACT-TIL) as patients naïve to these treatments.

19 Aug 2021

Remote controlling of CAR-T cells with heat to precisely target tumors

A team of researchers led by bioengineers at the Georgia Institute of Technology is expanding the precision and ability of a revolutionary immunotherapy that is already transforming oncology. CAR T-Cell therapy has been hailed by patients, clinical-researchers, investors, and the media as a viable cure for some cancers.

18 Aug 2021

Dysregulation of innate lymphoid cells drives colon cancer progression and immunotherapy resistance

An immune cell subset called innate lymphoid cells (ILC3s) protects against colorectal cancer, in part by helping to maintain a healthy dialogue between the immune system and gut microbes, according to a new study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian. The finding opens the door to new strategies for treating this type of cancer.

17 Aug 2021

New clinical trial investigates aspirin as part of new treatment for triple negative breast cancer

An innovative new study is trialing whether giving aspirin, commonly used as pain relief, alongside immunotherapy drug avelumab could improve its effectiveness for people affected by breast cancer.

17 Aug 2021

Experimental drug and immunotherapy combination shows promise in bladder cancer study

A new study in mice found that adding the experimental drug entinostat to an immunotherapy-like treatment substantially boosted cancer remission.

16 Aug 2021

Immunotherapy News and Research

Latest Immunotherapy News and Research

Development of SARS-CoV-2 antibody escape variants in an immunocompromised individual

FDA grants seven years of marketing exclusivity for Octapharma’s Octagam 10%

DNMT2/TRDMT1 gene knockout may potentiate adverse effects related to drug-induced senescence

Adding berzosertib to standard treatment for metastatic urothelial cancer does not extend patient survival

MSK researchers identify potential biomarker of response to checkpoint immunotherapy

Researchers identify mechanism for formation of rare colorectal cancer subtype

New artificial blood vessel platform for predicting organ transplant rejection

Study finds a new line of drugs to stimulate myelin repair in multiple sclerosis

Intestinal microorganisms help regulate anti-tumor immune responses to radiation therapy, study finds

UCLA scientists receive $1 million translational award to advance CAR T cell therapy for rare melanomas

ICL fluorescent label homogenously penetrates the glioblastoma brain tumors

New PULSAR radiation-therapy strategy achieves better tumor control

New prediction model can identify NSCLC patients who are not likely to respond to immunotherapy

Researchers create a novel strategy for developing an effective TB vaccine

Study in dogs may lead to better understanding of how gliomas affect the immune system

Prior treatment may impact efficacy of ACT-TIL in patients with metastatic melanoma

Remote controlling of CAR-T cells with heat to precisely target tumors

Dysregulation of innate lymphoid cells drives colon cancer progression and immunotherapy resistance

New clinical trial investigates aspirin as part of new treatment for triple negative breast cancer

Experimental drug and immunotherapy combination shows promise in bladder cancer study

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Immunotherapy News and Research

Latest Immunotherapy News and Research

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Newsletters you may be interested in