Metabolism News and Research

Latest Metabolism News and Research

At-home saliva test to diagnose adrenal insufficiency makes a difference to patients' health

A study into the use of an at-home test which uses saliva rather than blood to diagnose adrenal insufficiency, which has been developed by scientists at the University of Sheffield with funding from the National Institute for Health and Care Research, and tested in Sheffield endocrine patients at Sheffield Teaching Hospitals NHS Foundation Trust, is making a difference to the health of patients and could reduce time to diagnosis.

6 Jan 2023

Marine plankton samples can help study the connections between ocean pollution and rates of chronic illnesses

Using samples from an almost century-old, ongoing survey of marine plankton, researchers at University of California San Diego School of Medicine suggest that rising levels of manmade chemicals found in parts of the world's oceans might be used to monitor the impact of human activity on ecosystem health, and may one day be used to study the connections between ocean pollution and land-based rates of childhood and adult chronic illnesses.

6 Jan 2023

Cells live longer when they exchange metabolic products with each other

When cells exchange metabolic products with other cells, they live longer. This new finding comes from a research team at Charité – Universitätsmedizin Berlin, which made the discovery in a study using yeast cells.

6 Jan 2023

Researchers show how liver cancer cells hijack circadian clock machinery to divide and spread

The most common type of liver cancer, hepatocellular carcinoma (HCC), is already the third leading cause of cancer-related deaths globally - and cases are on the rise, both in the U.S. and worldwide.

6 Jan 2023

History of obesity produces changes in innate immunity and neuroinflammation

A history of obesity caused by a high-fat diet produces changes in innate immunity that can promote inflammatory disease – changes that persist even after weight loss and a return to normal metabolism, according to a new study in mice.

5 Jan 2023

Research findings open the door to new strategies for promoting muscle function during aging

Proven to protect against a wide array of diseases, exercise may be the most powerful anti-aging intervention known to science.

5 Jan 2023

Study details the “immunometabolic editing” mechanism of tumor evolution

A Ludwig Cancer Research study has discovered that the immune system's surveillance of cancer can itself induce metabolic adaptations in the cells of early-stage tumors that simultaneously promote their growth and equip them to suppress lethal immune responses.

5 Jan 2023

Researchers elucidate the mechanism behind the formation of pores in mitochondrial membrane

Mitochondria are considered to be the power plants of cells and are essential for human metabolism. Dysfunction in 40 percent of mitochondrial proteins are associated with human diseases, which is why mitochondria also play an important role in medical research.

5 Jan 2023

Intestinal bacteria in multiple sclerosis patients vary with disease activity, study finds

Multiple sclerosis patients do not have the same bacteria in their intestines as healthy people. There are also differences in the composition and function of the bacteria in the intestines of multiple sclerosis patients, depending on whether their illness is active, and whether they are in treatment.

5 Jan 2023

What is the role of SARS-CoV-2 non-structural protein 2 in repressing host antiviral immunity?

Researchers uncovered a novel mechanism that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other coronaviruses (CoVs) use to exploit host antiviral immune system to facilitate their replication.

5 Jan 2023

Mediterranean diet may benefit health in part by incorporating moderate wine consumption

Many public health warnings have been issued against alcohol consumption, even in small quantities, though the evidence for such strict limits is controversial. The current study, published in the MDPI journal Nutrients, is a narrative review focused on clearing up some of the confusion associated with alcoholic drinks.

4 Jan 2023

New insights into the bioavailability and hepatoxicity risk of neonicotinoids

Researchers quantified the residues of eight neonicotinoids in human bile samples to understand the association between internal neonicotinoid exposure and hepatotoxic outcomes.

4 Jan 2023

The relationship between metabolic disease and alternations in lipid homeostasis

Researchers assessed the function of lipids in metabolic diseases.

4 Jan 2023

Physical activity inhibits the production of insulin

When a fruit fly starts walking or flying, its insulin-producing cells are immediately inhibited. This could be one explanation for why exercise promotes health.

4 Jan 2023

The interrelationship between diet, physical health, and depression

A recent Journal of Affective Disorders study examined the interrelationship between diet, physical health, and depression.

4 Jan 2023

The metabolic links between diet-induced changes in the gut and NASH

Scientists reviewed the metabolic association between diet-induced alterations in the gut and NASH

4 Jan 2023

Technical advances expand the application of mass spectrometry imaging in pharmaceutical research

Announcing a new publication for Acta Materia Medica journal. Mass spectrometry imaging (MSI) has been shown to be a valuable tool through nearly every stage of the preclinical drug research and development (R&D) pipeline, and even to the early phase of clinical pharmaceutical evaluation.

3 Jan 2023

Salk scientists find a system-wide, molecular impact of time-restricted eating in mice

Numerous studies have shown health benefits of time-restricted eating including increase in life span in laboratory studies, making practices like intermittent fasting a hot topic in the wellness industry.

3 Jan 2023

Salk scientists show how a microprotein can increase appetite in mice

Obesity and metabolic diseases, such as diabetes, are extremely common in the United States. Tiny proteins called microproteins have long been overlooked in research, but new evidence demonstrates that they have an important role in metabolism.

3 Jan 2023

Phase III trial shows noninferiority of VV116 compared to nirmatrelvir–ritonavir among adults with mild-to-moderate COVID-19 at risk of progression

Researchers presented the results of a phase III randomized controlled trial of oral SARS-CoV-2 antiviral VV116.

3 Jan 2023

Metabolism News and Research

Latest Metabolism News and Research

At-home saliva test to diagnose adrenal insufficiency makes a difference to patients' health

Marine plankton samples can help study the connections between ocean pollution and rates of chronic illnesses

Cells live longer when they exchange metabolic products with each other

Researchers show how liver cancer cells hijack circadian clock machinery to divide and spread

History of obesity produces changes in innate immunity and neuroinflammation

Research findings open the door to new strategies for promoting muscle function during aging

Study details the “immunometabolic editing” mechanism of tumor evolution

Researchers elucidate the mechanism behind the formation of pores in mitochondrial membrane

Intestinal bacteria in multiple sclerosis patients vary with disease activity, study finds

What is the role of SARS-CoV-2 non-structural protein 2 in repressing host antiviral immunity?

Mediterranean diet may benefit health in part by incorporating moderate wine consumption

New insights into the bioavailability and hepatoxicity risk of neonicotinoids

The relationship between metabolic disease and alternations in lipid homeostasis

Physical activity inhibits the production of insulin

The interrelationship between diet, physical health, and depression

The metabolic links between diet-induced changes in the gut and NASH

Technical advances expand the application of mass spectrometry imaging in pharmaceutical research

Salk scientists find a system-wide, molecular impact of time-restricted eating in mice

Salk scientists show how a microprotein can increase appetite in mice

Phase III trial shows noninferiority of VV116 compared to nirmatrelvir–ritonavir among adults with mild-to-moderate COVID-19 at risk of progression

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging