Metabolism

Metabolism is the means by which the body derives energy and synthesizes the other molecules it needs from the fats, carbohydrates and proteins we eat as food, by enzymatic reactions helped by minerals and vitamins.

What is Anabolism?

Anabolism is the process by which the body utilizes the energy released by catabolism to synthesize complex molecules. These complex molecules are then utilized to form cellular structures that are formed from small and simple precursors that act as building blocks.

What is Metabolism?

Science of Metabolism

Metabolism Key Biochemicals

Metabolism Catabolism

Metabolism Energy Transformations

Xenobiotics and Redox Metabolism

Gibbs Free Energy and Metabolism

Metabolism Evolution

Metabolism Investigation and Manipulation

Metabolism History

Metabolism Control

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Metabolism Thermodynamics

What are Cytochrome P450 (CYP) Enzymes?

Science of Metabolism

Latest Metabolism News and Research

Researchers uncover potential glycine-based treatment for NAFLD

A new study further implicates low levels of the amino acid glycine in development of nonalcoholic fatty liver disease, or NAFLD. It also suggests addressing this might hold the key to a future treatment for the disease.

3 Dec 2020

Study shows beneficial effects of blackcurrants on post-meal glucose response

Blackcurrants have a beneficial effect on post-meal glucose response, and the required portion size is much smaller than previously thought, a new study from the University of Eastern Finland shows.

3 Dec 2020

Researchers create first map of microbiome of dental black plaque in adults

The dark pigmentations that appear around the gums on dental enamel have a bacterial origin and there is currently no definitive therapy to remove it entirely.

3 Dec 2020

CNRS develops new patented technique that reveals energy status of cells

A procedure that may help personalise anticancer therapies has just been developed by the CNRS, INSERM, and Aix-Marseille University scientists at the Centre d'Immunologie de Marseille-Luminy, in association with colleagues from the University of California San Francisco and the Marseille Public University Hospital System (AP-HM), with support from Canceropôle Provence-Alpes-Côte d'Azur.

2 Dec 2020

Cancer cells exhibit metabolic changes that make them vulnerable to ferroptosis

If there is a silver lining in cancer's chaotic biology, it's that the same traits that give cancer cells a growth advantage often present opportunities for sabotaging them.

2 Dec 2020

Study shows how parasite that causes Chagas disease resists current therapies

New insight on how a parasite can resist current therapies has been published today in the open-access eLife journal.

2 Dec 2020

Previously uncharacterized protein regulates mitochondrial NAD transporter

For their growth, cells need various nutrients and vitamins. So-called solute carriers (SLC), proteins that can transport such substances across the boundaries of cellular membranes, play a central role in metabolism.

1 Dec 2020

Researchers describe cellular mediator that makes muscle adaptation to exercise possible

The onset of any physical exercise program causes muscle pain that can hinder movements as simple as getting up from a sofa. With time and a little persistence, the muscles become accustomed to the effort, developing more strength and endurance.

1 Dec 2020

Older people in wealthy countries consume more alcohol, finds study

A new global study finds older people in wealthy countries consume more alcohol than their counterparts in middle-income countries, on average, although a higher cost of alcohol is associated with less frequent drinking.

1 Dec 2020

Researchers show strong link between Takotsubo syndrome and impaired thyroid function

Researchers have found a new hypothesis for explaining Takotsubo cardiomyopathy, also known as broken heart syndrome.

1 Dec 2020

Multiple pregnancies may affect the body's physical aging process

Having children doesn't just make you feel like you've aged overnight -- a new study led by Penn State researchers found that the number of times a person gives birth may also affect the body's physical aging process.

1 Dec 2020

New book serves as reference guide for CNS drugs

The primary objective of this 4-volume book series is to educate PharmD students on the subject of medicinal chemistry. The book set Medicinal Chemistry for Pharmacy Students serves as a reference guide to pharmacists on aspects of the chemical basis of drug action.

1 Dec 2020

Good cholesterol helps SARS-CoV-2 enter cells

The researchers explained that the SARS-CoV-2 can infect human host cells after its viral spike protein (SARS-2-S) binds to a cellular surface receptor called the angiotensin-converting enzyme 2 (ACE2).

30 Nov 2020

Researchers reveal link between gut bacteria and vitamin D levels

Our gut microbiomes -- the many bacteria, viruses and other microbes living in our digestive tracts -- play important roles in our health and risk for disease in ways that are only beginning to be recognized.

30 Nov 2020

Study: Plant-based diet boosts metabolism

A plant-based diet boosts after-meal burn, leads to weight loss, and improves cardiometabolic risk factors in overweight individuals, according to a new randomized control trial published in JAMA Network Open by researchers with the Physicians Committee for Responsible Medicine.

30 Nov 2020

Study outlines a new role for pregnancy-associated plasma protein A in gestational diabetes

Laboratory research and analysis of epidemiological data by Silvia Corvera, MD, and Tiffany Moore Simas, MD, MPH, MEd, and colleagues show that low levels of a protein commonly seen in screening tests for chromosomal disorders during the first trimester of pregnancy is associated with adipose tissue remodeling, glucose resistance and gestational diabetes mellitus in pregnant women.

30 Nov 2020

Mild electrical stimulation with heat shock exerts protective effect against nephrotic syndrome

A research team from Kumamoto University in Japan has found that the combination of weak pulsed electrical current and heat exerts anti-inflammatory and anti-fibrotic effects in the kidneys, as well as a protective effect against nephrotic syndrome (NS) by inhibiting apoptosis (cell death) of kidney cells.

30 Nov 2020

Could the keto diet help prevent or mitigate severe COVID-19?

A new study published in the journal of Translational Medicine reports that the ketogenic diet (KD) may be useful in this area, with its track history of effectual reduction of fat mass, anti-inflammatory and immunomodulatory effects, and consequent improvement of cardiovascular health.

30 Nov 2020

Female reproductive hormones may be protective against COVID-19

In an article recently published in Trends in Endocrinology & Metabolism, Graziano Pinna from the University of Illinois in Chicago outlines some of the evidence suggesting that female reproductive hormones may play a role in the sex bias that has been observed in coronavirus disease 2019 (COVID-19).

29 Nov 2020

Study exposes human olfactory and brain cells as genuine viral targets of SARS-CoV-2

In a study published in the iScience journal, a research group from Switzerland shows that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptors and entry genes are expressed in the human olfactory neuroepithelial cells and brain by observing key molecular players implicated in the infectious process

29 Nov 2020