Metabolism

Metabolism is the means by which the body derives energy and synthesizes the other molecules it needs from the fats, carbohydrates and proteins we eat as food, by enzymatic reactions helped by minerals and vitamins.

What is Anabolism?

Anabolism is the process by which the body utilizes the energy released by catabolism to synthesize complex molecules. These complex molecules are then utilized to form cellular structures that are formed from small and simple precursors that act as building blocks.

Metabolism Key Biochemicals

Gibbs Free Energy and Metabolism

Metabolism Thermodynamics

An Overview of Nucleotide Metabolism

Metabolism Energy Transformations

Metabolism Control

Metabolism Investigation and Manipulation

What are Coenzymes?

What is Metabolism?

Science of Metabolism

See more featured articles »

Xenobiotics and Redox Metabolism

What are Cytochrome P450 (CYP) Enzymes?

Metabolism Catabolism

Metabolism Evolution

Metabolism History

Latest Metabolism News and Research

Gut microbes may fuel allergic rhinitis symptoms

The study identifies gut microbiome alterations in allergic rhinitis, suggesting a gut-nose axis that could inform new treatment approaches for this condition.

17 Nov 2025

Preclinical study shows aged garlic extract improves memory and reduces anxiety

Long-term aged garlic extract supplementation improved specific anxiety-related behaviors and enhanced memory and learning in aging mice. Proteomic profiling revealed extensive hippocampal and cortical molecular changes linked to synaptic signaling, neuroplasticity, and stress-response pathways.

16 Nov 2025

Dash diet cuts diabetes complications by targeting blood pressure kidney health and inflammation

The DASH diet supports metabolic health in people with diabetes by improving blood pressure, renal function, lipids, and modest glycemic markers while reducing risks linked to vascular and inflammatory pathways. Its broad nutrient-driven mechanisms also benefit related conditions such as neuropathy, PCOS, and retinopathy, making it a versatile tool for cardiometabolic care.

16 Nov 2025

DeepTarget: A new tool for drug repurposing in oncology

One person's side effect could be another person's treatment if we expand our perspective on small molecule drug targets, according to a new study published November 5, 2025, in npj Precision Oncology.

14 Nov 2025

Understanding leptin's dual function in MAFLD pathogenesis

Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, intricately linked with obesity, type 2 diabetes (T2DM), and metabolic syndrome.

14 Nov 2025

Hypertension may induce early gene expression changes in brain cells

Hypertension impairs blood vessels, neurons and white matter in the brain well before the condition causes a measurable rise in blood pressure, according to a new preclinical study from Weill Cornell Medicine investigators.

14 Nov 2025

Exploring m6A RNA modification as a therapeutic target in cardiovascular disorders

Emerging research highlights the transformative potential of m6A RNA modification in the diagnosis and treatment of cardiovascular diseases (CVDs).

14 Nov 2025

Off-label GLP-1 use highlights the cultural pressures driving body anxieties

New obesity drugs that were designed to treat diabetes and obesity are increasingly being used off-label by people without these conditions to achieve slimness and social approval rather than health gains. This perspective maps how such pharmacological thinness interacts with stigma, beauty ideals, digital culture, and inequality, and calls for multinational, intersectional research to understand its full impact.

13 Nov 2025

Scientists reveal how prolonged UV exposure weakens cellular defense against skin cancer

Sunlight is vital for human health as it helps the body produce essential nutrients, such as vitamin D. However, too much sun exposure can significantly increase the risk of skin cancer.

13 Nov 2025

Cornell team unveils high-resolution tool for tracking kinase activity

Cornell researchers have developed a powerful new biosensor that reveals, in unprecedented detail, how and where kinases – enzymes that control nearly all cellular processes – turn on and off inside living cells.

13 Nov 2025

Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory

Replacing APOE4 with APOE2 in adult mice rapidly reshapes brain lipids and gene expression, even after development is complete. This switch, especially when targeted to astrocytes, reduces amyloid burden, dampens gliosis, and improves associative memory despite E2-like peripheral lipid risks.

12 Nov 2025

Potential breakthrough in treating acute kidney injury with ceramide-targeting drugs

Serious damage to short-term kidney function-known as acute kidney injury, or AKI-can be fatal and also increase the risk of irreversible chronic kidney disease. It can be triggered by stressors ranging from sepsis to heart surgery, and it affects more than half of ICU patients.

12 Nov 2025

Natural compound and exercise work together to enhance musculoskeletal health in aging bodies

A new research paper was published in Volume 17, Issue 10 of Aging-US on October 1, 2025, titled "L-β-aminoisobutyric acid (L-BAIBA) in combination with voluntary wheel running exercise enhances musculoskeletal properties in middle-age male mice."

11 Nov 2025

New precision therapies reshape the future of pancreatitis treatment

Pancreatitis remains a major global health burden, encompassing acute pancreatitis (AP), chronic pancreatitis (CP), and autoimmune pancreatitis (AIP).

11 Nov 2025

Study reveals how neural excitability and learning potential fluctuate across the day

Our brains do not react in a fixed, mechanical way like electronic circuits. Even if we see the same scene every day on our commute to work, what we feel - and whether it leaves a lasting impression - depends on our internal state at that moment.

11 Nov 2025

Targeting RNA splicing errors protects against tau-induced neurodegeneration

Alzheimer's Disease (AD), the leading cause of dementia, affects nearly 40 million individuals globally, resulting in a gradual loss of memory and independence. Despite extensive research over the past decades, no treatments have been found that can halt or reverse the progression of this devastating disease.

11 Nov 2025

Researchers achieve long-term remission with novel T cell therapies for HPV-related cancers

Researchers from Rutgers Cancer Institute, New Jersey's only National Cancer Institute (NCI) - designated Comprehensive Cancer Center, and RWJBarnabas Health, along with colleagues from the National Cancer Institute, a center of the National Institutes of Health, announced findings from two HPV-related studies that highlight the potential of novel T cell therapies to achieve long-lasting remission and complete tumor regression in patients with advanced epithelial cancers.

10 Nov 2025

Ultra-processed food consumption increases the risk for prediabetes in young adults

More than half of calories consumed in the United States come from ultra-processed foods (UPFs), items like fast food and packaged snacks that are often high in sodium, sugar and unhealthy fats.

10 Nov 2025

GLP-1 drugs beat metformin for weight control in teens with type 2 diabetes

In youth newly diagnosed with type 2 diabetes, GLP-1–based therapies, including semaglutide and tirzepatide, achieved similar blood sugar control but significantly greater reductions in body mass index than metformin. These findings highlight the potential of high-potency GLP-1 agents as effective monotherapy options in managing obesity and glycemic control in adolescents.

10 Nov 2025

Blood protein pattern linked to increased risk of hereditary atherosclerosis

A specific pattern of proteins in the blood may reflect an increased risk of hereditary atherosclerosis. This is shown in a new study from Karolinska Institutet, examining close relatives of people who had suffered a heart attack at a young age.

10 Nov 2025