Metabolism

Metabolism is the means by which the body derives energy and synthesizes the other molecules it needs from the fats, carbohydrates and proteins we eat as food, by enzymatic reactions helped by minerals and vitamins.

What is Anabolism?

Anabolism is the process by which the body utilizes the energy released by catabolism to synthesize complex molecules. These complex molecules are then utilized to form cellular structures that are formed from small and simple precursors that act as building blocks.

What is Metabolism?

Science of Metabolism

Metabolism Key Biochemicals

Metabolism Catabolism

Metabolism Energy Transformations

Xenobiotics and Redox Metabolism

Gibbs Free Energy and Metabolism

Metabolism Evolution

Metabolism Investigation and Manipulation

Metabolism History

Metabolism Control

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Metabolism Thermodynamics

What are Cytochrome P450 (CYP) Enzymes?

Science of Metabolism

An Overview of Nucleotide Metabolism

What are Coenzymes?

Latest Metabolism News and Research

UCL scientists identify new immunotherapy to combat hepatitis B virus

Scientists at UCL have identified a new immunotherapy to combat the hepatitis B virus (HBV), the most common cause of liver cancer in the world.

14 May 2021

Farxiga approved in the US for the treatment of chronic kidney disease in patients at risk of progression with and without type-2 diabetes

Approval is the most significant advancement in the treatment of chronic kidney disease in more than 20 years. In DAPA-CKD Phase III trial, Farxiga demonstrated unprecedented reduction in the risk of the composite of worsening of renal function, end-stage kidney disease and cardiovascular or renal death.

From AstraZeneca 14 May 2021

Do labels on commercial kefir products report microbial levels correctly?

A recent study in the journal JDS Communications reports the results of an analysis of five brands of kefir on the US market, indicating the need for stricter regulation of this field.

14 May 2021

Phosphatidic acid is a key common substrate for hepatitis C and SARS-CoV-2 replication

A new study, released as a preprint on the bioRxiv* server, focuses on the lipid molecule called phosphatidic acid (PA), showing its crucial role in the replication of this virus, and thus its potential as a target for therapeutic intervention.

13 May 2021

New study may help develop senolytic drugs that target senescent immune cells

In a study recently published in Nature University of Minnesota Medical School researchers found that senescent immune cells are the most dangerous type of senescent cell.

13 May 2021

Measuring metabolic 'fluxes' could help scientists advance new tuberculosis drugs

Mycobacterium tuberculosis is incredible in that it can survive for decades within its human host. It does this by varying its diet to successfully steal nutrients from the human host including immune cells; it is known to acquire and absorb multiple carbon sources from the body during infection.

12 May 2021

Let's Talk about Long-COVID (Chronic COVID Syndrome)

In this interview, Germano Tarantino, the Scientific Director at PharmaNute S.p.A, talks to NewsMed about long-COVID (also known as chronic COVID syndrome).

From PharmaNutra Spa 12 May 2021

Sepsis can cause alterations in the functioning of defense cells that lead to death

An article published in Frontiers in Immunology suggests that sepsis can cause alterations in the functioning of defense cells that persist even after the patient is discharged from hospital.

12 May 2021

Natural products a rich source for novel antiviral compounds

In a recent review in the journal Viruses, researchers look at natural products that can be identified as potential alternative antiviral agents. The reviewers discussed the antiviral activities of several natural products towards DNA and RNA viruses with an analytical approach. The researchers detailed the cellular/viral targets of the active molecules and their impact on the infection and viral replication cycle.

10 May 2021

Normalizing cholesterol metabolism in microglia alleviates chronic neuropathic pain

Chemotherapy can induce a painful peripheral neuropathy (CIPN), a chronic condition and common adverse effect for cancer patients undergoing treatment.

10 May 2021

Complementary medicines for weight loss cannot be justified based on current evidence, review suggests

The first global review of complementary medicines (herbal and dietary supplements) for weight loss in 16 years--combining 121 randomized placebo-controlled trials including nearly 10,000 adults--suggests that their use cannot be justified based on the current evidence.

8 May 2021

Targeted therapies could exploit unique metabolic features of pancreatic cancer cells

Probing the unique biology of human pancreatic cancer cells in a laboratory has yielded unexpected insights of a weakness that can be used against the cells to kill them.

7 May 2021

Researchers identify genetic cause of a rare neurological disorder

In a paper published today in Nature Communications, an international group of collaborators led by researchers at UPMC Children's Hospital of Pittsburgh have identified a genetic cause of a rare neurological disorder marked by developmental delay and loss of coordination, or ataxia.

7 May 2021