Metabolism News and Research

Latest Metabolism News and Research

Blood proteins reveal which aging cells may raise disease risk

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16 Jun 2026

New biomarker predicts gastric cancer outcomes from CT scans

Researchers at the State University of Campinas (UNICAMP) in São Paulo, Brazil, have identified a new biomarker that may help determine the prognosis for patients with gastric cancer, the fifth most common type of cancer worldwide.

16 Jun 2026

Heart tissue repair drug may also help repair and regenerate damaged kidney tissues

A drug previously developed at UCLA to help heart tissue repair itself after a heart attack might also help kidney tissue repair and regenerate, researchers have found.

16 Jun 2026

Gut bacteria may help explain why fatigue appears before illness

A small study of healthy Japanese adults found that fatigue was associated with distinct gut microbiome, microbial gene, and fecal metabolite patterns. The findings suggest fatigue may track with altered microbial energy metabolism and oxidative stress-related functional potential, but larger longitudinal studies are needed to test causality and clinical value.

16 Jun 2026

Gut microbes control liver genes by flipping DNA switches

A local research study led by scientists from the A*STAR Genome Institute of Singapore (A*STAR GIS) has uncovered how the gut microbiome can influence gene activity in the liver by acting on short stretches of regulatory DNA that function like molecular "switches".

15 Jun 2026

Global study links rising obesity to premature heart disease deaths

Researchers are warning that obesity is reshaping the global cardiovascular disease crisis, as trend data covering 204 countries reveal that heart disease now peaks in people aged 50-54 rather than the elderly and increasingly in South Asia, where rates have grown more than three times faster than global averages, according to a study being presented Monday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

15 Jun 2026

The importance of ketones from a clinical and medical perspective

In this interview, News-Medical talks to Marcin Pacek, senior director of medical and scientific affairs in Europe for Nova Biomedical, about the importance of ketones in a medical and clinical setting.

From Nova Biomedical 15 Jun 2026

Single-dose gene therapy extends healthy lifespan in older mice

A research team from the Universitat Autònoma de Barcelona (UAB) has shown that a one-time administration of a gene therapy expressing the metabolic factor FGF21 can prolong health span in old mice.

15 Jun 2026

Researchers map rare DHDDS disease mechanism using lab-grown mini brains

Variants in the DHDDS gene cause a severe neurodegenerative condition, characterized by tremors, seizures, coordination and learning difficulties, usually manifesting in early childhood. This Parkinson's-like condition is extremely rare, and until recently, parents were told that there was nothing that could be done to slow down its progression.

15 Jun 2026

Glucosamine may worsen Alzheimer’s by fueling abnormal brain glycosylation

A Nature Metabolism study identifies brain hyperglycosylation as a metabolic driver of Alzheimer’s disease, with increased N-glycan biosynthesis seen in human AD tissue and mouse models. Reducing glycosylation improved memory in AD mice, while glucosamine worsened memory deficits in 5xFAD mice and was associated with poorer outcomes in dementia patients.

14 Jun 2026

Short-chain oat fiber helps steady glucose and ease gut symptoms in pilot trial

A 14-day open-label pilot study in 63 healthy adults found that short-chain oat fiber was well tolerated at doses up to 20 g/day and was associated with improved gastrointestinal symptom scores.

14 Jun 2026

Genetic data may predict steroid side effect risk

Oral corticosteroids (OCSs) are widely used and effective in the treatment of chronic inflammatory conditions such as arthritis, asthma, and autoimmune diseases. They work by reducing inflammation, relieving pain, and calming the immune system.

14 Jun 2026

Testosterone benefits older men with T2D risk when combined with lifestyle changes

Testosterone treatment may improve body composition, glucose metabolism and sexual desire in some older men at high risk of type 2 diabetes (T2D), but the benefits require engagement in a lifestyle program, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

14 Jun 2026

New guideline recommends tailored care for precocious puberty

Some subgroups of children with precocious puberty-such as older girls with slowly progressing puberty-may not need the same level of testing or treatment, according to a new Endocrine Society Clinical Practice Guideline released today.

14 Jun 2026

Cellular process discovery may lead to new cancer treatments

A molecular geneticist at Montana State University has discovered a cellular process once believed impossible by scientists – the creation of the amino acid cysteine within a living cell when the cell's primary systems to do so fail. The discovery may one day lead to new cancer treatments.

12 Jun 2026

Gut microbiome may determine bone loss severity in primary hyperparathyroidism

Primary hyperparathyroidism (PHPT) is a common endocrine disorder characterized by excessive secretion of parathyroid hormone (PTH).

12 Jun 2026

Antibody profiles offer insights into long Covid cognitive symptoms

Persistent symptoms after COVID-19 infection continue to affect millions of people worldwide, even as the number of acute infections has declined.

12 Jun 2026

New combination therapy improves outcomes in high-risk leukemia

A research team from the Department of Medicine, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has developed a novel combination therapy that significantly improves treatment outcomes and survival in patients with acute myeloid leukaemia (AML) with FLT3 gene mutations.

11 Jun 2026

Oral semaglutide improves blood sugar, weight, and liver markers in real-world diabetes care

A nationwide Finnish registry study of 7,249 GLP-1RA-naïve adults with type 2 diabetes found that once-daily oral semaglutide was associated with 12-month improvements in HbA1c, body weight, lipid markers, and ALT.

11 Jun 2026

Trial finds prunes do not outperform calcium and vitamin D for male bone density

A one-year randomized trial found that daily prune supplementation did not improve total or lumbar spine bone mineral density in older men susceptible to, or with, osteopenia. Although some bone turnover biomarkers differed between prune and control groups, these changes did not translate into measurable bone density benefits beyond calcium and vitamin D3 supplementation.

11 Jun 2026