Metabolism News and Research

Latest Metabolism News and Research

Study identifies brain mechanism behind pregnancy-related food cravings

Why do food cravings become so strong during pregnancy? Researchers at LSU's Pennington Biomedical Research Center, in collaboration with colleagues, have identified a brain mechanism that may help explain how pregnancy changes the motivation to seek certain highly palatable foods.

18 Sep 2026

Scientists discover metabolite fueling aggressive brain tumor growth

Virtually all high-grade, aggressive gliomas in adults accumulate massive amounts of a metabolite called guanidinoacetate (GAA) that overstimulates nearby neurons and promotes tumor growth, according to new research from scientists at Children’s Medical Center Research Institute at UT Southwestern (CRI) published in Cell.

18 Sep 2026

More physical activity linked to lower type 2 diabetes risk in adults

Celastrol reduces cholestatic liver injury by inhibiting specific protein

Cholestasis occurs when bile formation, secretion, or flow is impaired, causing toxic bile acids to accumulate and trigger inflammation and liver-cell damage.

17 Sep 2026

Time-restricted eating may slow early-stage Huntington's disease

A simple change in when people eat may offer a promising new approach for Huntington's disease, according to research led by Oregon Health & Science University.

17 Sep 2026

Study identifies bile acid that helps reduce excess fat accumulation in the liver

Non-alcoholic fatty liver disease (NAFLD), now known as metabolic dysfunction-associated steatotic liver disease (MASLD), is a common condition that causes excess fat to build up in the liver, affecting about one-quarter of adults worldwide.

17 Sep 2026

New MRI measure maps blood flow and cellular organization

Researchers from the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC have developed a new, noninvasive way to examine how blood flow and cellular organization align across the layers of the living human brain.

17 Sep 2026

High estrogen alters brain circuit causing temporary memory impairment during pregnancy

Many women usually say the same thing during pregnancy: they walk into a room and forget why, misplace their keys or struggle to follow a conversation.

17 Sep 2026

Shatavari may affect more than hormones, and the gut could help explain why

A review in Nutrients examined how bioactive compounds in Asparagus racemosus (Shatavari) may influence cognitive health through the microbiota-gut-brain axis, estrogen-related signaling, neuroinflammation, oxidative stress, and neurotransmitter regulation. Evidence from computational, cellular, animal, and limited human studies suggests several plausible biological pathways, but key questions remain about bioavailability, brain exposure, dosing, and clinical efficacy.

16 Sep 2026

Fermented dairy was linked to lower mortality, but the pattern shifted at higher intakes

Analysis of 37,366 US adults found that fermented dairy consumption was associated with lower all-cause and cardiovascular mortality, with consumers showing adjusted hazards 18% and 20% lower, respectively, than non-consumers. Dose-response analyses indicated that the inverse association was concentrated at intakes below about 150 grams per day, while the observational study could not establish causality.

16 Sep 2026

Study: Multiple dietary patterns linked to slower biological aging

A study by DZNE finds that healthy eating is associated with slower biological aging-and that there is more than one way to eat healthily.

16 Sep 2026

Exercise usually helps the brain. During a 15-day fast, the story was different

In a 28-day controlled study of 22 healthy adults, 15 days of complete fasting produced a glucose-to-ketone metabolic shift and selectively affected attention and implicit learning while time perception remained relatively stable. Moderate-intensity exercise during early fasting was associated with poorer performance on some learning measures, while fasting also increased sleepiness and reduced calmness at some time points.

15 Sep 2026

Male contraception has barely changed in a century. What comes next?

A review traces more than 5,000 years of male contraception, from early penile sheaths and the development of modern condoms and vasectomy to today's search for reversible alternatives. Researchers are now testing hormonal gels, non-hormonal compounds and vas-occlusive technologies, although these approaches remain at different stages of preclinical and clinical development.

15 Sep 2026

Cannabis-derived nanovesicles showed early antitumor potential in mice

Researchers developed a Cannabis sativa hairy root culture system that produced stable plant-derived nanovesicles capable of promoting dendritic cell maturation and activating T-cell responses through TLR2- and TLR4-associated signaling. Oral administration also restored selected immune responses in immunosuppressed mice and suppressed tumor growth in an E.G7 lymphoma model, providing preliminary evidence for their immunomodulatory and antitumor potential.

15 Sep 2026

What children eat may leave a measurable signature in their blood

Researchers analyzed 236 blood metabolites in 421 children to examine metabolic signatures associated with three dietary patterns characterized by core foods, animal protein sources, or poor-quality fats and sugars. The results identified distinct, biologically plausible metabolite patterns across dietary exposures, although most individual associations did not survive multiple-testing correction and require validation in independent cohorts.

15 Sep 2026

KAIST team uncovers how neurons deliver RNA to distant regions

Much like a courier reading an address on a package, neurons must deliver RNA to the precise locations where it is needed.

15 Sep 2026

Risk factors for cardiovascular-kidney-metabolic disease can be identified in young children

Risk factors for cardiovascular-kidney-metabolic disease, a health condition made up of heart disease, kidney disease, diabetes, and obesity, can be identified in children as young as 8, UTHealth Houston researchers discovered.

11 Sep 2026

Proteomic signatures reveal early signs of cardiovascular-kidney-metabolic disease in children

Researchers at Vanderbilt Health, UTHealth Houston and the University of North Carolina at Chapel Hill have identified early signs of cardiovascular-kidney-metabolic disease (CKMD) in children as young as 8 years old that potentially can be reversed with a new class of weight loss drugs used widely by adults

11 Sep 2026

Early studies hint that ketones may affect pathways linked to PTSD

An integrative review found that ketogenic therapy may influence metabolic, inflammatory, oxidative stress, and neurotransmitter pathways implicated in PTSD, with animal studies and small human studies reporting early signs of symptom improvement. Human evidence remains limited to very small cohorts, case reports, and pilot studies, and controlled trials have yet to establish clinical efficacy.

11 Sep 2026

Innovative device improves real-time monitoring of donated lungs

More than three-quarters of donated lungs offered for transplantation are not used, according to the UK's National Institute for Health and Care Excellence, contributing to a chronic shortage of organs for patients with end-stage lung disease.

10 Sep 2026