Metabolism News and Research

Latest Metabolism News and Research

Study shows how prostate tumors rewire metabolism to resist therapy

Prostate tumors can rewire amino acid metabolism to override the normal brakes on cholesterol production, a process that may fuel hormone therapy resistance, according to a study by Weill Cornell Medicine investigators.

20 Aug 2026

Microglial differences found in genetic and sporadic frontotemporal dementia patients

A study by the University of Eastern Finland revealed for the first time clear differences in the function and gene expression of microglial cells from patients with genetic and sporadic types of frontotemporal dementia.

20 Aug 2026

New studies reveal hidden control hub for MYC-driven cancers

In a rare pair of papers published back-to-back in the journal Genes & Development, research teams led by senior author Anindya Bagchi, PhD, associate professor in the Cancer Genome and Epigenetics Program at Sanford Burnham Prebys Medical Discovery Institute, establish a unified framework that governs one of cancer's most powerful master regulators.

19 Aug 2026

Colorectal tumors may damage nerves before chemotherapy

Researchers at The University of Texas MD Anderson Cancer Center found that, in preclinical models of colorectal cancer, tumors can start damaging peripheral nerves before chemotherapy begins.

19 Aug 2026

Global study reveals rising chronic kidney disease burden in women

Chronic kidney disease is now the seventh leading cause of death among noncommunicable diseases globally, affecting 11–13% of the adult population.

19 Aug 2026

First high-resolution cell-by-cell map tracks tomato root and fungal partnership

Scientists at VIB and Ghent University have produced the first high-resolution, cell-by-cell map of how tomato roots respond to colonization by arbuscular mycorrhizal fungi.

18 Aug 2026

Key molecule released during exercise strengthens muscles

Scientists have discovered that a key molecule released during exercise strengthens muscles, improves exercise performance and could be a therapeutic treatment for muscle damage caused by type 2 diabetes.

18 Aug 2026

Whole grains, legumes and vegetables stand out in a major review of diabetes diets

Healthy plant-based diets rich in whole grains, legumes, fruits, vegetables, nuts, and seeds are associated with better glycemic control and a lower risk of type 2 diabetes. The review finds that food quality and processing matter more than simply avoiding animal foods, while unhealthy plant-based patterns and higher red and processed meat intake are associated with greater metabolic risk.

18 Aug 2026

Researchers uncover hidden function of known tuberculosis bacterium gene

The complete genome for the tuberculosis bacterium was sequenced and published in 1998. Since then, scientists have deciphered about two-thirds of TB's genes. Or have they?

17 Aug 2026

Sprint exercise sends a very different molecular signal through the body

Sprint-interval exercise triggers a much larger and faster shift in circulating proteins and metabolites than moderate-intensity exercise, revealing distinct patterns of predicted communication between organs. The findings suggest that exercise intensity shapes systemic molecular signaling, with skeletal muscle and adipose tissue emerging as potential source and target tissues linked to cardiometabolic health.

16 Aug 2026

Opening the black box of biological aging clocks

What do "epigenetic clocks" actually measure? These lab tests have become popular tools for studying biological aging, or how the body's cellular function changes at a faster or slower rate than expected.

14 Aug 2026

New study focuses on starving bacteria to prevent Lyme disease

Triggered by a near painless tick bite, Lyme disease causes severe pain and inflammation for more than 475,000 people in the U.S annually, according to the Centers for Disease Control.

13 Aug 2026

Mitochondrial protein deficiency drives increased fat intake and obesity

Obesity is a global health concern that can contribute to diabetes, cardiovascular disease, and other metabolic disorders.

13 Aug 2026

Finnish study links habitual coffee consumption to healthier body metabolism

Coffee is one of the world's most widely consumed beverages, and previous research has linked its consumption to a lower risk of conditions such as type 2 diabetes and cardiovascular disease.

13 Aug 2026

Your social life may leave a mark on how fast you age

Positive social experiences were associated with longer survival, while childhood adversity predicted shorter survival in a 1,309-person longitudinal cohort followed for nearly 15 years. Epigenetic aging, particularly GrimAge2, emerged as the strongest potential pathway linking social experiences with mortality risk.

12 Aug 2026

Liver’s internal clock coordinates daily metabolic communication, study finds

What if one of the keys to a healthier metabolism is understanding how and when the liver communicates with the rest of the body?

12 Aug 2026

Mitochondrial rewiring may explain why orthoflaviviruses harm humans but persist in mosquitoes

Orthoflaviviruses reshape mitochondrial structure, metabolism, redox signaling, and quality control differently across human and mosquito models, helping explain their contrasting infection outcomes. The review highlights mitochondrial pathways that may support acute cellular damage in vertebrates but persistent, non-lethal infection in mosquitoes, pointing to potential antiviral targets.

12 Aug 2026

AI-based methods help uncover hidden roots of tumor metastasis

A cancerous tumor is not a single enemy. It is made up of many different cell populations that can behave in very different ways.

12 Aug 2026

Mitochondrial gene RTN4IP1 drives triple-negative breast cancer metastasis

Triple-negative breast cancer accounts for approximately 15% of all breast cancer cases. It is characterized by the absence of estrogen receptor, progesterone receptor, and HER2 expression, rendering it insensitive to conventional endocrine and targeted therapies.

12 Aug 2026

Researchers find unexpected protein regulator of leukemia drug sensitivity

How cells respond to the leukemia drug 6-thioguanine still holds surprises: A new study, led by researchers from CeMM and the University of Oxford identifies NUDT5 as an unexpected regulator of drug sensitivity and reveals that its role has nothing to do with its enzymatic activity.

12 Aug 2026