Metabolism News and Research

Latest Metabolism News and Research

Obesity impairs key immune cells but bariatric surgery reverses damage

New Maynooth University (MU) research led by the Department of Biology's Dr Ciara Flynn, working within the research group of Prof Andrew Hogan at the Kathleen Lonsdale Institute for Human Health Research has found that obesity can impair key immune cells that help protect the body against infection and cancer.

22 Oct 2026

AGA/AASLD joint guideline evaluates newer medications for primary biliary cholangitis

For the first time, a joint guideline from the American Gastroenterological Association (AGA) and American Association for the Study of Liver Diseases (AASLD) evaluates newer medications for primary biliary cholangitis (PBC), the most common cholestatic disease in adults.

22 Oct 2026

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

Discover expert insights into single-cell proteomics, revealing protein diversity and non-canonical biology with advanced mass spectrometry

From Bruker Daltonics 22 Oct 2026

Blocking specific proteins protects beta cells om excessive cellular stress

Researchers at Weill Cornell Medicine have identified a molecular pathway that contributes to the death of insulin-producing beta cells in the pancreas.

21 Oct 2026

Study shows circadian rhythms vary across different cell types

Biological clocks coordinate the spatiotemporal organization of metabolism with diurnal time cues, and bulk-tissue RNA sequencing studies in mammals have revealed widespread circadian (about 24 h) gene expression in mice and non-human primates.

21 Oct 2026

Altered fatty acid metabolism drives glioblastoma growth and treatment resistance

Glioma is the most common primary malignant brain tumor in adults, and glioblastoma (GBM), particularly IDH (Isocitrate dehydrogenase)-wildtype disease, has the poorest prognosis.

21 Oct 2026

Greenwood Genetic Center researcher wins major grant to explore cellular metabolism and glycosylation

Heather Flanagan-Steet, PhD, Associate Director of Research at the Greenwood Genetic Center (GGC), has received a $1.4 million, five-year Maximizing Investigators' Research Award (MIRA) R35 grant from the National Institutes of Health's National Institute of General Medical Sciences.

21 Oct 2026

Could a hormone from our bones reveal early signs of insulin resistance?

Research reveals a link between osteocalcin and insulin resistance in obese children, suggesting early metabolic changes before glucose tolerance impairment.

21 Oct 2026

Why the same healthy diet may not work the same way for everyone

A review published in Nutrients proposes a seven-pillar precision nutrition framework that combines biological, behavioral, and environmental information to tailor dietary interventions throughout life. The authors identify potential benefits for cardiovascular, respiratory, blood, and sleep health, while emphasizing the need for further clinical trials to establish effective, accessible, and personalized nutritional strategies.

20 Oct 2026

New PET imaging approach detects nearly all kidney cancer lesions

A new PET imaging approach detected 97.9% of lesions in clear cell renal cell carcinoma (ccRCC), potentially giving clinicians a more complete picture of the location and extent of a patient's disease, according to research presented today at the 39th Annual Congress of the European Association of Nuclear Medicine (EANM'26).

20 Oct 2026

New study identifies protein factor linked to chronic liver disease

The mechanisms that cause the world's most common chronic liver disease — Metabolic dysfunction-associated steatotic liver disease (MASLD) — to develop and progress are not still fully understood.

20 Oct 2026

Could eating whey protein before meals help reduce blood sugar spikes?

A narrative review of 57 randomized trials found that milk and dairy products have inconsistent effects on long-term blood sugar control in adults with type 2 diabetes or prediabetes. Whey protein consumed before meals more consistently reduced short-term blood sugar spikes, but further research is needed to establish whether these benefits persist over time.

19 Oct 2026

Researchers use mitochondrial uncouplers to target breast cancer metastasis

Mitochondrial serine catabolic pathway (MSCP), also called serine, glycine, and one-carbon metabolism, is essential for cancer cells to produce amino acids, one-carbon units, and reducing equivalents.

19 Oct 2026

Blood pressure drug losartan boosts metabolism by stimulating brown fat

Losartan, a drug commonly prescribed for high blood pressure, boosts brown adipose tissue or "brown fat" activity and enhances its metabolism, according to a preclinical study by Weill Cornell Medicine, Rockefeller University and Memorial Sloan Kettering Cancer Center researchers.

19 Oct 2026

Could this flowering plant help people lose body fat?

Lythrum salicaria extract supplementation led to body fat reduction in a clinical trial, suggesting a promising plant-based approach to weight management.

19 Oct 2026

Menopause isn't the end of the story for the ovaries

Research reveals that postmenopausal ovaries remain active, showing molecular remodeling linked to inflammation and potential implications for women's health.

19 Oct 2026

Your age may not tell the whole story about your health, but your blood could

Researchers analyzed plasma metabolites from 18,476 individuals aged 1 to 96 years and developed two metabolomic aging measures to assess biological aging, chronic disease, and mortality risk. Accelerated metabolomic aging was associated with greater risks of chronic disease and death, while a separate mortality-linked measure provided additional information about health status and disease burden beyond conventional clinical assessments.

18 Oct 2026

Bisphenol mixtures alter breast tissue development in lab-grown human models

Exposure to common chemicals may alter how normal human breast tissue develops, according to a new study from researchers at Tufts University School of Medicine and Boston University

15 Oct 2026

Women with low bone density reported less pain after taking pine bark extract

A randomized clinical trial involving 67 women with osteopenia or stable osteoporosis found that three months of Pycnogenol® supplementation improved self-reported bodily pain and vitality scores compared with placebo. However, overall disease-specific quality of life did not significantly improve, and the six-month findings were insufficient to establish long-term benefits or safety.

15 Oct 2026

Targeting the STING pathway could help prevent osteoporosis

As we age, our bones become weak and brittle, a process called osteoporosis. This bone loss is caused by changes in the cells within the bone marrow microenvironment, such as elevated fat and inflammation-promoting immune cells.

15 Oct 2026