Metabolism News and Research

Latest Metabolism News and Research

Exploring testosterone's influence on cardiovascular, metabolic, reproductive, and mental health

For decades, testosterone has been recognized as the primary driver of male reproductive development and secondary sex characteristics.

1 Sep 2025

Why metformin could protect the brain by rewiring mitochondria

Metformin boosts human oligodendrocyte differentiation and myelination across stem-cell, organoid, and chimera models. The study links these effects to mitochondrial metabolic shifts, supporting its potential as a therapy for multiple sclerosis.

1 Sep 2025

How plant compounds could target Alzheimer’s disease from multiple angles

This review highlights how dietary polyphenols modulate Alzheimer’s disease biology through antioxidant, anti-inflammatory, and multi-target mechanisms, supported by in-silico docking analyses. Despite promise, challenges in bioavailability and brain delivery remain key hurdles to clinical translation.

31 Aug 2025

Ultra-processed foods affect sperm quality and metabolism even without extra calories

A controlled crossover trial in Cell Metabolism found that ultra-processed foods increase weight, fat mass, LDL:HDL cholesterol, and alter reproductive hormones in men, with some effects independent of calorie load. These diets also showed trends toward reduced sperm motility, shifts in pollutants, and transient inflammatory responses, highlighting risks beyond excess calories.

31 Aug 2025

Discovery of mitochondrial microprotein opens path to obesity and aging therapies

Like bees breathing life into gardens, providing pollen and making flowers blossom, little cellular machines called mitochondria breathe life into our bodies, buzzing with energy as they produce the fuel that powers each of our cells.

29 Aug 2025

Insights into clinical features and genetic variants of Cornelia de Lange syndrome in China

Cornelia de Lange syndrome (CdLS) is a rare genetic disorder with symptoms, including facial anomalies (such as fused eyebrows, short nose, upturned nose tip, and downturned mouth corners), growth retardation, small head (microcephaly), developmental delays, cognitive impairments, excess hair growth, and limb anomalies.

29 Aug 2025

Male and female bovine embryos show distinct development paths

Cornell researchers have uncovered the genetic triggers that cause male and female bovine embryos to develop differently, as early as seven to eight days after fertilization.

29 Aug 2025

Proteomic study reveals new drug targets in gastric signet ring cell carcinoma

Gastric signet ring cell carcinoma (GSRCC) is a distinct subtype of gastric cancer (GC) with unique epidemiological and pathogenic characteristics.

29 Aug 2025

Glycosylation emerges as a key player in kidney disease progression

Kidney diseases affect nearly 700 million people worldwide and are a growing cause of mortality and health care costs.

29 Aug 2025

What are the benefits of chewing gum beyond oral health?

Chewing gum offers health benefits beyond oral care, enhancing performance and recovery, but research gaps for children and seniors need addressing.

29 Aug 2025

UNSW researchers identify key protein that regulates fat storage in cells

UNSW research has shed light on how cells in the body manage and store fat, potentially offering new insights into health.

29 Aug 2025

Stress in mothers causes eczema in newborn mice through immune cell changes

Maternal prenatal stress in mice disrupts fetal mast cell programming, triggering eczema-like skin inflammation and heightened sensitivity after birth. The findings reveal how corticosterone-driven immune and neuronal changes in utero may set the stage for pediatric eczema risk.

28 Aug 2025

Ultra-processed foods harm reproductive and metabolic health

Over the past 50 years, rates of obesity and type-2 diabetes have soared, while sperm quality has plummeted. Driving these changes could be the increasing popularity of ultra-processed foods, which have been linked to a range of poor health outcomes.

28 Aug 2025

Cardiovascular outcomes worsen in patients with mental health conditions

Every 34 seconds, someone in the United States dies from heart disease. As nearly half of the country suffers from some form of cardiovascular disease (CVD), another 1 in 4 adults experience a mental health disorder in their lifetime, signaling an inevitable overlap.

28 Aug 2025

Gut disorders forecast Alzheimer’s and Parkinson’s risk years before diagnosis

Study maps clinical, genetic, and proteomic links between gut-brain disorders and neurodegeneration, showing how diabetes, vitamin D deficiency, and bowel disorders forecast Alzheimer’s and Parkinson’s years in advance. Multimodal models in biobanks highlight early detection and personalized prevention opportunities.

28 Aug 2025

Probiotic enhances cholesterol drug efficacy but raises safety concerns at high doses

A recent study published in Engineering has shed light on the complex interactions between probiotics and drugs, particularly focusing on the effects of the probiotic Lacticaseibacillus paracasei Zhang (LCZ) on the cholesterol-lowering drug lovastatin.

28 Aug 2025

High protein diet linked to increased risk of cancer-associated venous thromboembolism

Next to cancer recurrence or progression, cardiovascular diseases are the leading causes of death in cancer survivors.

28 Aug 2025

New swallowable device enables noninvasive gut nerve stimulation

Scientists have long struggled with how to study the gut's vast nervous system - often called the body's 'second brain' - without damaging it.

28 Aug 2025

Breathwork may mimic psychedelic effects through brain changes

Breathwork while listening to music may induce a blissful state in practitioners, accompanied by changes in blood flow to emotion-processing brain regions, according to a study published August 27, 2025, in the open-access journal PLOS One by Amy Amla Kartar from the Colasanti Lab in the Department of Clinical Neuroscience at Brighton and Sussex Medical School, U.K., and colleagues.

28 Aug 2025

Chronic neuron overactivation may drive Parkinson's disease progression

Certain brain cells are responsible for coordinating smooth, controlled movements of the body. But when those cells are constantly overactivated for weeks on end, they degenerate and ultimately die.

28 Aug 2025

Metabolism News and Research

Latest Metabolism News and Research

Exploring testosterone's influence on cardiovascular, metabolic, reproductive, and mental health

Why metformin could protect the brain by rewiring mitochondria

How plant compounds could target Alzheimer’s disease from multiple angles

Ultra-processed foods affect sperm quality and metabolism even without extra calories

Discovery of mitochondrial microprotein opens path to obesity and aging therapies

Insights into clinical features and genetic variants of Cornelia de Lange syndrome in China

Male and female bovine embryos show distinct development paths

Proteomic study reveals new drug targets in gastric signet ring cell carcinoma

Glycosylation emerges as a key player in kidney disease progression

What are the benefits of chewing gum beyond oral health?

UNSW researchers identify key protein that regulates fat storage in cells

Stress in mothers causes eczema in newborn mice through immune cell changes

Ultra-processed foods harm reproductive and metabolic health

Cardiovascular outcomes worsen in patients with mental health conditions

Gut disorders forecast Alzheimer’s and Parkinson’s risk years before diagnosis

Probiotic enhances cholesterol drug efficacy but raises safety concerns at high doses

High protein diet linked to increased risk of cancer-associated venous thromboembolism

New swallowable device enables noninvasive gut nerve stimulation

Breathwork may mimic psychedelic effects through brain changes

Chronic neuron overactivation may drive Parkinson's disease progression

Quality, Patient Safety and Innovation Manager at Elsevier

How Bruker worked with the University of Manchester on mapping the dynamics of complex protein

Real-time Raman monitoring for pharmaceutical hot melt extrusion