Metabolism News and Research

Latest Metabolism News and Research

Maternal childhood trauma linked to rapid weight gain in baby boys

Adverse situations experienced by the mother during childhood – such as neglect or physical, psychological or sexual violence – can trigger excessive weight gain in male children as early as the first two months of life.

23 Apr 2025

Body image concerns drive interest in GLP-1 weight loss drugs, study finds

A new study from Rutgers University links higher body dissatisfaction, BMI, and maladaptive weight loss behaviors with interest in GLP-1 medications for weight loss. Conversely, body appreciation appears to protect against this interest, especially in the face of potential side effects.

23 Apr 2025

Researchers uncover link between heart attack severity and circadian rhythm

The molecular mechanism behind why heart attacks can vary in severity depending on the time of day has been uncovered by researchers at UTHealth Houston, potentially paving the way for innovative treatments that align with the natural circadian rhythm.

23 Apr 2025

New approach may prevent neurotoxic protein aggregates in ALS

Researchers at Goethe University, Johannes Gutenberg University Mainz and Kiel University discover possible method for preventing protein aggregates – Cluster4Future PROXIDRUGS research project.

23 Apr 2025

DT-109 shows promise in treating atherosclerosis and liver disease

A drug candidate, previously successful at treating severe fatty liver disease, reduces atherosclerosis - a primary driver of cardiovascular death worldwide - in large mammals, a study suggests.

23 Apr 2025

Interferon regulatory factor 8 identified as key driver of liver fat buildup in NAFLD

Non-alcoholic fatty liver disease (NAFLD) is a hepatic metabolic syndrome resulting from lipid metabolic imbalance. Interferon regulatory factor 8 (IRF8) is well known for its roles in immune cell differentiation and tumor pathogenesis; however, its role in regulating glucose homeostasis and lipid metabolism remains unclear.

22 Apr 2025

Disruption of sterol biosynthesis by prescription drugs: A hidden threat to brain development

A powerful editorial published today in Brain Medicine raises alarm about a previously overlooked threat to brain development and public health: the disruption of sterol biosynthesis by common prescription medications.

22 Apr 2025

Obesity alters the rhythm of liver’s starvation response

Researchers led by Keigo Morita and Shinya Kuroda of the University of Tokyo have revealed a temporal disruption in the metabolism of obese mice when adapting to starvation despite no significant structural disruptions in the molecular network.

22 Apr 2025

New $15 million study aims to understand cardiovascular and kidney disease risk factors in women

Research teams from Augusta University, Massachusetts General Hospital and The Ohio State University will lead a $15 million project dedicated to studying the various ways that risk factors for cardiovascular and kidney diseases impact women.

22 Apr 2025

New noninvasive method for early diabetes risk detection

The highs and lows of blood glucose aren't just an energy rollercoaster; they could be a key to detecting diabetes risk early and spare you a needle prick or two.

22 Apr 2025

Major breakthrough could turn IV drugs into oral treatments for brain cancer and Alzheimer's

A research team led by scientists at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) made a major breakthrough with the potential to turn IV drugs into oral treatments for diseases like brain cancer and Alzheimer's disease.

21 Apr 2025

New research aims to illuminate the causes of age-related macular degeneration

It's an unfortunate fact of aging: Live long enough and, eventually, reading this sentence will get difficult, even impossible.

21 Apr 2025

Vitamin D curbs colorectal cancer by boosting immunity and blocking tumor growth

Review highlights how vitamin D, particularly its active form calcitriol, modulates immune responses, inflammation, and tumor progression to help prevent colorectal cancer (CRC). Evidence suggests adequate vitamin D levels and supplementation reduce CRC risk and improve outcomes.

21 Apr 2025

Molecular drivers and emerging treatments in anaplastic thyroid cancer

Anaplastic thyroid cancer (ATC), a rare yet highly aggressive malignancy, continues to represent a major clinical challenge.

20 Apr 2025

GOT2 as a metabolic and immunologic target in pancreatic cancer

A new wave of scientific interest is spotlighting GOT2—glutamic-oxaloacetic transaminase 2—as a compelling therapeutic target in the fight against pancreatic cancer, one of the most lethal and treatment-resistant malignancies.

20 Apr 2025

Lipid metabolism as a driver of therapy resistance in triple negative breast cancer

Lipid metabolism has emerged as a central player in the progression and therapy resistance of breast cancer, particularly the aggressive subtype known as triple-negative breast cancer (TNBC).

20 Apr 2025

Mitochondrial pyruvate carrier structure solved after fifty years

Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria, the 'powerhouses' of our cells, allows us to make the fuel we need from sugars, a process vital to all life on Earth.

18 Apr 2025

Targeting PGM3 offers new hope against deadly brain tumor

Researchers have found that targeting an enzyme called PGM3 can help stop the growth of glioblastoma, the most dangerous type of brain tumor.

18 Apr 2025

Monell study offers renewed hope for people living with Bardet-Biedl Syndrome

A Monell Chemical Senses Center study published this week in the Journal of Clinical Investigation offers renewed hope for individuals living with Bardet-Biedl Syndrome (BBS), a rare genetic disorder characterized by early-onset obesity, compulsive eating, and cognitive impairments.

18 Apr 2025

Study examines how COX-2 regulates ferroptosis in chronic liver injury

Ferroptosis plays an essential role in chronic liver diseases, and cyclooxygenase-2 (COX-2) affects liver fibrosis through multiple mechanisms. +

18 Apr 2025

Metabolism News and Research

Latest Metabolism News and Research

Maternal childhood trauma linked to rapid weight gain in baby boys

Body image concerns drive interest in GLP-1 weight loss drugs, study finds

Researchers uncover link between heart attack severity and circadian rhythm

New approach may prevent neurotoxic protein aggregates in ALS

DT-109 shows promise in treating atherosclerosis and liver disease

Interferon regulatory factor 8 identified as key driver of liver fat buildup in NAFLD

Disruption of sterol biosynthesis by prescription drugs: A hidden threat to brain development

Obesity alters the rhythm of liver’s starvation response

New $15 million study aims to understand cardiovascular and kidney disease risk factors in women

New noninvasive method for early diabetes risk detection

Major breakthrough could turn IV drugs into oral treatments for brain cancer and Alzheimer's

New research aims to illuminate the causes of age-related macular degeneration

Vitamin D curbs colorectal cancer by boosting immunity and blocking tumor growth

Molecular drivers and emerging treatments in anaplastic thyroid cancer

GOT2 as a metabolic and immunologic target in pancreatic cancer

Lipid metabolism as a driver of therapy resistance in triple negative breast cancer

Mitochondrial pyruvate carrier structure solved after fifty years

Targeting PGM3 offers new hope against deadly brain tumor

Monell study offers renewed hope for people living with Bardet-Biedl Syndrome

Study examines how COX-2 regulates ferroptosis in chronic liver injury

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?