Metabolism News and Research

Latest Metabolism News and Research

How artificial light interferes with liver health

People who work against their internal clock over a long period of time increase the risk of fatty liver. The correlations are complex, but one research team in Bochum is trying to get to the bottom of the issue.

4 Nov 2025

Urolithin A recharges aging immune cells and boosts mitochondrial fitness in midlife adults

Urolithin A, a natural postbiotic known to trigger mitophagy, rejuvenated key immune cell functions in healthy middle-aged adults after 28 days. The trial showed a shift toward a youthful, energy-efficient CD8⁺ T-cell profile and enhanced bacterial clearance without inflammatory side effects.

3 Nov 2025

Combined analysis of three blood tests enhances heart attack risk prediction

A combined analysis of blood tests to measure three biomarkers linked to higher risk of cardiovascular disease-lipoprotein a (Lp(a)), remnant cholesterol and high-sensitivity C-reactive protein (hsCRP)-may help identify high-risk individuals earlier and guide more personalized prevention strategies, according to a preliminary study to be presented at the American Heart Association's Scientific Sessions 2025.

3 Nov 2025

Scientists explore why black rice deserves a bigger place in modern diets

Researchers reviewed the nutritional composition, therapeutic benefits, and industrial uses of black rice, highlighting its potential as a functional food. The study highlights the role of black rice in managing blood sugar, cholesterol, and inflammation, while also advocating for more robust human trials and sustainable cultivation methods.

2 Nov 2025

Research shows citrus and grape compounds may protect against type 2 diabetes

A six-month clinical trial found that a supplement combining citrus and grape extracts, hesperidin, and chromium significantly reduced fasting blood glucose in prediabetic adults. Participants also saw improved cholesterol and triglyceride levels, returning many to normal metabolic health.

2 Nov 2025

Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers

Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and disease progression.

31 Oct 2025

Exploring the link between underweight status and gut microbiota composition in Japanese women

Low body weight in young women has been linked to a range of health concerns, including disrupted menstrual cycles, infertility, weakened immune function, and a long-term decline in bone density.

31 Oct 2025

Sensory effects of flavanols trigger physiological responses in the brain

Astringency is a dry, puckering, rough, or sandpapery sensation in the mouth caused by plant-derived polyphenols.

31 Oct 2025

Understanding how biological sex and gender inequities contribute to suboptimal sepsis treatment

Sepsis continues to be a leading cause of mortality in ICUs worldwide. Despite advances in early detection and treatment, standardized antibiotic dosing frequently ignores patient-level variability-especially that associated with sex-related physiology and gender-influenced care disparities.

31 Oct 2025

Reducing ketone levels and increasing exercise capacity could help manage diabetic ketoacidosis

A researcher at the University of Houston finds management of diabetic ketoacidosis may center around reducing ketone levels in diabetic patients and increasing exercise capacity for better health outcomes.

30 Oct 2025

Two microbial metabolites compete to control the cells' protein building machinery

The microbiome-the trillions of bacteria, viruses, and fungi that live quietly in our body-plays a crucial role in shaping human health by providing a variety of micronutrients necessary for vital functions.

30 Oct 2025

Does fasting earlier in the day improve metabolism? This study says no

In a randomized crossover trial of 31 women with overweight, early and late time-restricted eating (TRE) produced no improvement in insulin sensitivity or cardiometabolic markers under isocaloric conditions. Both schedules, however, shifted internal circadian clocks, highlighting that meal timing affects biological rhythms more than metabolic outcomes.

30 Oct 2025

Aligning your body clock may protect your heart and metabolism, says AHA

A new American Heart Association scientific statement highlights how maintaining circadian health through regular sleep, light exposure, meal timing, and exercise may reduce cardiometabolic disease risk. Disrupting these daily rhythms can impair glucose regulation, blood pressure, and cardiovascular function.

29 Oct 2025

AI indelibly transforms solid tumor drug development

Artificial intelligence (AI) is fundamentally reshaping the landscape of solid tumor (ST) drug development.

29 Oct 2025

Experimental compound reduces cell death, inflammation, and organ damage in diabetes

An experimental compound reduced the cell death, inflammation, and organ damage seen with diabetes.

29 Oct 2025

Hydroxytyrosol from olives shows new promise as a brain-protective compound

This review highlights hydroxytyrosol's role as a neuroprotective agent, activating key pathways for mental and vascular health through olive-derived compounds.

29 Oct 2025

Circadian rhythm disruptions may increase the risk of cardiovascular disease

As modern lifestyles increasingly challenge the body's natural circadian rhythm, the American Heart Association is spotlighting the potential health consequences of regular disruptions to our body's internal clock with a new scientific statement published today in its flagship journal Circulation.

28 Oct 2025

Tryptophan deficiency in breast milk may explain health challenges in children born to mothers with HIV

A new UCLA study reveals that breast milk from women living with HIV contains significantly lower levels of tryptophan, an essential amino acid likely important for infant immune function, growth, and brain development.

28 Oct 2025

Researchers discover a previously unknown genetic cause for microcephaly

Microcephaly is a congenital malformation that leads to a significantly reduced brain size and is often accompanied by developmental delay.

28 Oct 2025

Eating peanuts while pregnant may influence how a child’s genes respond to breastfeeding

Maternal peanut and peanut butter consumption during pregnancy and breastfeeding shaped DNA methylation patterns in children, particularly in genes regulating neurodevelopment and inflammation. These findings suggest maternal diet can prime offspring epigenetic sensitivity to breastfeeding duration.

27 Oct 2025

Metabolism News and Research

Latest Metabolism News and Research

How artificial light interferes with liver health

Urolithin A recharges aging immune cells and boosts mitochondrial fitness in midlife adults

Combined analysis of three blood tests enhances heart attack risk prediction

Scientists explore why black rice deserves a bigger place in modern diets

Research shows citrus and grape compounds may protect against type 2 diabetes

Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers

Exploring the link between underweight status and gut microbiota composition in Japanese women

Sensory effects of flavanols trigger physiological responses in the brain

Understanding how biological sex and gender inequities contribute to suboptimal sepsis treatment

Reducing ketone levels and increasing exercise capacity could help manage diabetic ketoacidosis

Two microbial metabolites compete to control the cells' protein building machinery

Does fasting earlier in the day improve metabolism? This study says no

Aligning your body clock may protect your heart and metabolism, says AHA

AI indelibly transforms solid tumor drug development

Experimental compound reduces cell death, inflammation, and organ damage in diabetes

Hydroxytyrosol from olives shows new promise as a brain-protective compound

Circadian rhythm disruptions may increase the risk of cardiovascular disease

Tryptophan deficiency in breast milk may explain health challenges in children born to mothers with HIV

Researchers discover a previously unknown genetic cause for microcephaly

Eating peanuts while pregnant may influence how a child’s genes respond to breastfeeding

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production