Metabolism News and Research

Latest Metabolism News and Research

Belzutifan demonstrates strong clinical activity in two rare neuroendocrine tumors

A multicenter Phase II clinical trial led by researchers at The University of Texas MD Anderson Cancer Center demonstrated significant tumor shrinkage and disease control in patients with advanced pheochromocytoma and paraganglioma (PPGL), two rare and potentially life-threatening neuroendocrine tumors.

18 Oct 2025

Study reveals how a microglial mutation increases risk for Alzheimer's disease

Dominika Pilat, PhD, and Ana Griciuc, PhD, of the Department of Neurology at Massachusetts General Hospital are the lead and senior authors of a paper published in Neuron, "The Gain-of-Function TREM2-T96K Mutation Increases Risk for Alzheimer's Disease by Impairing Microglial Function."

17 Oct 2025

European societies launch EndoCompass to guide the future of endocrine research

The European Society for Endocrinology (ESE) and the European Society for Paediatric Endocrinology (ESPE) have released today, 17 October 2025, the EndoCompass Research Roadmap: Directions for the Future of Endocrine Science.

17 Oct 2025

Research reveals how immune cells orchestrate the release of toxic granules

When immune cells strike, precision is everything. New research reveals how natural killer and T cells orchestrate the release of toxic granules – microscopic packages that destroy virus-infected or cancerous cells.

17 Oct 2025

Scientists discover why a powerful leukemia drug fails in most patients

Researchers from Rutgers Health and other institutions have discovered why a powerful leukemia drug eventually fails in most patients – and found a potential way to overcome that resistance.

17 Oct 2025

Study: Hidden fat inside the abdomen and liver may damage arteries

A new study led by researchers at McMaster University reveals that hidden fat deep inside the abdomen and liver may quietly damage arteries, even in people who appear healthy.

17 Oct 2025

Ganoderma lucidum protects against liver damage from high-fat diets

A long-term high-fat diet (HFD) exerts lipotoxic effects on multiple organs, particularly the liver, leading to metabolic diseases.

16 Oct 2025

New personalized therapy boosts tamoxifen effectiveness in breast cancer patients

Breast cancer is the most common cancer among women worldwide (WHO, 2023). The Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology (IKP) has now developed a new therapy in a clinical study that tailors hormone treatment for breast cancer to the individual patient.

16 Oct 2025

Researchers discover new genetic cause of hereditary optic atrophy

A research team from the Medical University of Vienna and the Medical University of Graz has discovered a previously unknown genetic cause of hereditary optic atrophy, a degenerative disease of the optic nerve associated with gradual loss of vision.

16 Oct 2025

Mass General Brigham study shows US obesity could jump from 40% to 70%

The prevalence of obesity in the United States could rise sharply under a new definition of obesity released earlier this year by the Lancet Diabetes and Endocrinology Commission.

16 Oct 2025

Fatty acids found to be a primary driver of triple-negative tumor growth

A team from Huntsman Cancer Institute at the University of Utah (the U) has found that triple-negative breast cancer is fueled by lipids and that these fatty acids are a key feature of obesity that promote tumor growth.

16 Oct 2025

Building muscle shown to protect against obesity-related organ damage

People with excess body fat who build and keep muscle may be less likely to develop obesity-induced heart, liver, or kidney damage or die early, according to a new study published in The Journal of Clinical Endocrinology & Metabolism.

15 Oct 2025

Study links gut dysbiosis with severe steatosis in MASLD

A new study in eGastroenterology links gut dysbiosis with severe steatosis in metabolic dysfunction–associated steatotic liver disease (MASLD).

15 Oct 2025

New triple action iron supplement restores iron levels without inflammation

Iron-deficiency anemia is a common condition marked by tiredness, headaches or ice cravings. But the oral iron supplements used to treat it can leave behind excess iron that causes inflammation and an upset stomach.

15 Oct 2025

New insights into MDMA therapy for PTSD and beyond

A comprehensive peer-reviewed invited review published today in Psychedelics by Dr. Kenji Hashimoto and colleagues (Dr. Mingming Zhao and Dr. Jianjun Yang) synthesizes the evolving landscape of MDMA-assisted psychotherapy, examining robust clinical evidence in treatment-resistant posttraumatic stress disorder while identifying promising applications in autism spectrum disorder, eating disorders, and existential distress

14 Oct 2025

Breakthrough enables large-scale cultivation of blood vessel cells

Scientists have discovered a method to induce human endothelial cells from a small biopsy sample to multiply in the laboratory, producing more than enough cells to replace damaged blood vessels or nourish organs for transplantation, according to a preclinical study by Weill Cornell Medicine investigators.

14 Oct 2025

Reducing sedentary behavior and increasing light physical activity can support metabolic health

New study shows that just 30 minutes of less sitting each day can improve the body's ability to utilise fats and carbohydrates for energy production.

14 Oct 2025

Researchers test 250-year-old heart medicine in patients with deadly pancreatic cancer

Researchers in Sweden are testing a 250-year-old medicine in patients with one of the world's deadliest cancers.

14 Oct 2025

New insights can reshape psychiatric practice across continents

In a compelling Genomic Press Interview published today in Genomic Psychiatry, Dr. Bruce M. Cohen discusses results and insights that are reshaping international approaches to understanding and treating neuropsychiatric disorders.

14 Oct 2025

Maternal PFAS levels can predict children's brain structural and functional outcomes

Researchers from the University of Turku and Turku University Hospital, Finland, and örebro University, Sweden, have discovered that the levels of PFAS in mothers' blood during pregnancy is associated with their children's brain structure and function.

13 Oct 2025

Metabolism News and Research

Latest Metabolism News and Research

Belzutifan demonstrates strong clinical activity in two rare neuroendocrine tumors

Study reveals how a microglial mutation increases risk for Alzheimer's disease

European societies launch EndoCompass to guide the future of endocrine research

Research reveals how immune cells orchestrate the release of toxic granules

Scientists discover why a powerful leukemia drug fails in most patients

Study: Hidden fat inside the abdomen and liver may damage arteries

Ganoderma lucidum protects against liver damage from high-fat diets

New personalized therapy boosts tamoxifen effectiveness in breast cancer patients

Researchers discover new genetic cause of hereditary optic atrophy

Mass General Brigham study shows US obesity could jump from 40% to 70%

Fatty acids found to be a primary driver of triple-negative tumor growth

Building muscle shown to protect against obesity-related organ damage

Study links gut dysbiosis with severe steatosis in MASLD

New triple action iron supplement restores iron levels without inflammation

New insights into MDMA therapy for PTSD and beyond

Breakthrough enables large-scale cultivation of blood vessel cells

Reducing sedentary behavior and increasing light physical activity can support metabolic health

Researchers test 250-year-old heart medicine in patients with deadly pancreatic cancer

New insights can reshape psychiatric practice across continents

Maternal PFAS levels can predict children's brain structural and functional outcomes

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production