Metabolism News and Research

Latest Metabolism News and Research

Time-restricted eating combined with exercise may boost fat loss

Time-restricted eating is the latest craze for people looking to lose weight, but whether it works is still the calorie-burning question.

26 Mar 2025

Novel drug nitisinone could help reduce malaria spread by killing mosquitoes

In the fight against malaria, controlling the mosquito population is crucial.

26 Mar 2025

Pass the (iodized) salt: Iodine deficiency drives frailty risk in people with diabetes

Lower iodine levels and use of non-iodized salt are linked to a higher risk of frailty in people with type 2 diabetes. This association is strongest in those with thyroid dysfunction, underscoring the importance of adequate iodine intake.

26 Mar 2025

Scientists uncover rare gene variants that help people live past 100

Researchers studying over 2,000 Ashkenazi Jewish centenarians uncovered two rare IGF-1 gene variants linked to exceptional longevity. These variants reduce IGF-1 receptor activity through either diminished receptor binding or lower circulating IGF-1 levels.

26 Mar 2025

This molecule links your diet to stroke and Alzheimer’s—here’s how to stop it

A new review explores how TMAO, a gut-derived metabolite from red meat and other foods, contributes to heart and brain diseases. It also highlights promising interventions—like plant-based diets, probiotics, and nutraceuticals—to lower TMAO levels and reduce health risks.

26 Mar 2025

Study shows red wine biomarkers in urine can predict inflammation levels

Researchers found that specific metabolites of resveratrol in urine accurately reflect red wine consumption. These biomarkers were linked to reduced inflammation in older adults at cardiovascular risk, unlike traditional food surveys.

25 Mar 2025

Early antibiotic exposure may boost risk of diabetes later in life

Exposure to antibiotics during a key developmental window in infancy can stunt the growth of insulin-producing cells in the pancreas and may boost risk of diabetes later in life, new research in mice suggests.

25 Mar 2025

Marathon running temporarily reduces brain myelin levels

Marathon running causes a temporary decline in brain myelin content, but levels return to normal within two months. This reversible change may reflect the brain tapping into myelin lipids as an emergency energy source during extreme exertion.

25 Mar 2025

Postpartum females show shift in temperature preferences due to brain changes

Mothers experience major metabolic adaptations during pregnancy and lactation to support the development and growth of the new life.

25 Mar 2025

Anti-inflammatory drugs may reduce metabolic disease risk by inhibiting the sweet taste receptor

Past studies have shown that the human sweet taste receptor conveys sweet perception in the mouth and may help regulate glucose metabolism throughout the body.

25 Mar 2025

C. diff uses toxic compound to gain competitive advantage in the gut

The pathogen C. diff - the most common cause of health care-associated infectious diarrhea - can use a compound that kills the human gut's resident microbes to survive and grow, giving it a competitive advantage in the infected gut.

25 Mar 2025

Novel global cooperative phenomena of cell interactions discovered in cervical cancer cells

A Japanese research team has discovered a novel global cooperative phenomena of cell interactions in cervical cancer cells. Their findings suggest that the cells are metabolically connected in a functional network.

25 Mar 2025

Targeting PCSK9 and APOA4 for the treatment of TMAO-induced cholelithiasis

Cholesterol synthesis and gallstone formation are promoted by trimethylamine-N-oxide (TMAO), a derivative of trimethylamine, which is a metabolite of gut microbiota.

25 Mar 2025

Simple changes in eating habits could help fight obesity

Obesity is linked to numerous health complications, including diabetes, cardiovascular disease, and fatty liver disease.

25 Mar 2025

Drinking diet drinks in pregnancy raises overweight risk in children, study finds

Daily consumption of artificially sweetened beverages (ASB) during pregnancy was linked to a modest but consistent increase in overweight risk in offspring from age 7 to 18. Surprisingly, sugar-sweetened beverages (SSB) were associated with a lower risk, though lifestyle differences may explain this.

25 Mar 2025

New brain metabolism model reveals key targets for reversing aging

The most comprehensive model of the brain’s metabolism, incorporating more than 16,800 biochemical interactions, has identified key targets to reverse the age-related decline in brain function.

25 Mar 2025

New insights into therapy resistance in breast cancer

A new review was published in Oncotarget, Volume 16, on March 13, 2025, titled "Signaling pathway dysregulation in breast cancer."

25 Mar 2025

New study links metabolic defects to Dravet syndrome

New research from the University of Colorado Anschutz Medical Campus is the first to identify defects related to metabolism (how the body processes and uses energy) in lymphoblast cell lines (LCLs) derived from blood samples of children with Dravet syndrome.

25 Mar 2025

ELRIG announces Prof Rory Johnson and Dr Shalini Andersson as keynote speakers at Therapeutic Oligonucleotides 2025

ELRIG, a not-for-profit, volunteer-led organization for the drug discovery community, today announced the keynote speakers for Therapeutic Oligonucleotides 2025 taking place at the AstraZeneca R&D site in Gothenburg, Sweden from 14-15 May. Prof Rory Johnson, Associate Professor, University College Dublin, and Dr Shalini Andersson, Vice President Nucleic Acid Therapeutics, AstraZeneca will lead this year's event focused on 'drugging the undruggable'.

25 Mar 2025

New brain circuit involved in motion sickness could help improve metabolic health

Motion sickness is a very common condition that affects about 1 in 3 people, but the brain circuits involved are largely unknown. In the current study published in Nature Metabolism, researchers at Baylor College of Medicine, the University of Texas Health Science Center at Houston and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital describe a new brain circuit involved in motion sickness that also contributes to regulating body temperature and metabolic balance.

24 Mar 2025

Metabolism News and Research

Latest Metabolism News and Research

Time-restricted eating combined with exercise may boost fat loss

Novel drug nitisinone could help reduce malaria spread by killing mosquitoes

Pass the (iodized) salt: Iodine deficiency drives frailty risk in people with diabetes

Scientists uncover rare gene variants that help people live past 100

This molecule links your diet to stroke and Alzheimer’s—here’s how to stop it

Study shows red wine biomarkers in urine can predict inflammation levels

Early antibiotic exposure may boost risk of diabetes later in life

Marathon running temporarily reduces brain myelin levels

Postpartum females show shift in temperature preferences due to brain changes

Anti-inflammatory drugs may reduce metabolic disease risk by inhibiting the sweet taste receptor

C. diff uses toxic compound to gain competitive advantage in the gut

Novel global cooperative phenomena of cell interactions discovered in cervical cancer cells

Targeting PCSK9 and APOA4 for the treatment of TMAO-induced cholelithiasis

Simple changes in eating habits could help fight obesity

Drinking diet drinks in pregnancy raises overweight risk in children, study finds

New brain metabolism model reveals key targets for reversing aging

New insights into therapy resistance in breast cancer

New study links metabolic defects to Dravet syndrome

ELRIG announces Prof Rory Johnson and Dr Shalini Andersson as keynote speakers at Therapeutic Oligonucleotides 2025

New brain circuit involved in motion sickness could help improve metabolic health

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