Metabolism News and Research

Latest Metabolism News and Research

New insights reveal EGFR as a target in KRAS-mutated colon cancer

KRAS mutations are among the most common genetic alterations in cancer and are considered particularly difficult to treat.

26 May 2025

Blood cell-free RNA signatures can predict preterm birth months in advance

Children born before 37 weeks of gestation have a considerably increased risk of dying before they reach the age of five.

25 May 2025

Large global study links higher alcohol intake to increased pancreatic cancer risk

A pooled analysis of over 2.4 million adults across four continents shows a modest but significant increase in pancreatic cancer risk with higher alcohol consumption. The risk is especially pronounced for beer and liquor, and at higher intake levels in men and women.

25 May 2025

Brain stem nerve cells hold key to safer weight loss treatments

A specific group of nerve cells in the brain stem appears to control how semaglutide affects appetite and weight - without causing nausea

23 May 2025

Muscle quality linked to cognitive health in middle age

Over the past decade, much research has focused on the connection between skeletal muscle health and cognitive disorders.

23 May 2025

Autophagy-based mechanism provides insight into Parkinson’s disease protein secretion

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells.

23 May 2025

Aging metabolism reduces effectiveness of CAR-T cell therapy

A Ludwig Cancer Research study has discovered that the metabolic decline that accompanies aging impairs the efficacy of CAR-T cell therapy, an immunotherapy in which T cells of the immune system are taken from patients, engineered to target cancer cells and reinfused into the same patients for treatment.

23 May 2025

Machine learning tool identifies metabolic clues in colorectal cancer

Scientists aiming to advance cancer diagnostics have developed a machine learning tool that is able to identify metabolism-related molecular profile differences between patients with colorectal cancer and healthy people.

22 May 2025

Metabolite profiles in spinal fluid predict mortality in tuberculous meningitis

Radboudumc researchers Kirsten van Abeelen, Edwin Ardiansyah, Sofiati Dian, Vinod Kumar, Reinout van Crevel and Arjan van Laarhoven used metabolomics to study cerebrospinal fluid (CSF) samples from tuberculous meningitis patients in Vietnam and Indonesia, with long-standing collaborators from Bandung and Jakarta (Indonesia), the Broad Institute (Boston) and the Oxford University Research Unit in Ho Chi Minh City (Vietnam).

22 May 2025

Unlocking the secrets of human longevity and healthy aging

Human healthy aging and longevity are complex phenomena influenced by a dynamic interplay of genetic, epigenetic, metabolic, immune, and environmental factors.

22 May 2025

Gut bacteria and diet found to affect cancer treatment outcomes

A Ludwig Cancer Research study has uncovered a surprising link between diet, intestinal microbes and the efficacy of cancer therapy.

22 May 2025

Cysteine depletion triggers rapid weight loss in mice

Mice genetically engineered to lack the ability to make the amino acid cysteine, and fed a cysteine-free diet, lost 30 percent of their body weight in just one week, a new study shows.

22 May 2025

Blood and urine tests reveal how much ultra-processed food you really eat, study finds

Researchers developed and validated blood and urine metabolite scores that objectively measure ultra-processed food (UPF) intake in adults. These biomarker profiles accurately distinguished between high- and low-UPF diets and may transform nutrition research and public health monitoring.

21 May 2025

Vitamin D supplements help preserve telomere length in aging adults

Results from the VITAL randomized controlled trial reveal that vitamin D supplementation helps maintain telomeres, protective caps at the ends of chromosomes that shorten during aging and are linked to the development of certain diseases.

21 May 2025

Microplastics in ultra-processed foods may fuel mental health risks, experts warn

New research highlights a possible link between microplastics in ultra-processed foods and rising rates of depression, anxiety, and sleep problems. Experts call for urgent investigation as microplastic accumulation in the human brain increases alongside ultra-processed food intake.

21 May 2025

Exploring the link between microbial balance and aging mechanisms

Aging is a multifaceted process driven by interconnected biological mechanisms, among which genomic instability and telomere attrition stand as primary hallmarks.

20 May 2025

Gut bacteria and genes jointly shape obesity risk, review reveals hidden links

Researchers examined the heritability of body mass index (BMI), highlighting that genetics and the gut microbiome both play major roles in obesity risk. The review emphasizes that maternal microbiome transmission and family environment may help explain “missing heritability” beyond known genetic factors.

20 May 2025

Cell Painting technology uncovers flavonoids with potential to treat bladder cancer

A team led by researchers at Baylor College of Medicine has identified flavonoids, natural compounds found in plants, that are toxic to bladder cancer cells cultured in the lab.

20 May 2025

NIH researchers develop poly-metabolite score to measure ultra-processed food intake

For the first time, researchers at the National Institutes of Health (NIH) identified patterns of metabolites in blood and urine that can be used as an objective measure of an individual's consumption of energy from ultra-processed foods.

20 May 2025

Personalized gene editing corrects fatal infant metabolic disorder in world-first treatment

Researchers have used a personalised base-editing gene therapy to successfully treat an infant with carbamoyl-phosphate synthetase 1 (CPS1) deficiency, a rare and life-threatening inborn error of metabolism. This pioneering approach chemically corrects the underlying mutation without cutting DNA, showing promise for precision treatment of ultrarare genetic disorders.

20 May 2025

Metabolism News and Research

Latest Metabolism News and Research

New insights reveal EGFR as a target in KRAS-mutated colon cancer

Blood cell-free RNA signatures can predict preterm birth months in advance

Large global study links higher alcohol intake to increased pancreatic cancer risk

Brain stem nerve cells hold key to safer weight loss treatments

Muscle quality linked to cognitive health in middle age

Autophagy-based mechanism provides insight into Parkinson’s disease protein secretion

Aging metabolism reduces effectiveness of CAR-T cell therapy

Machine learning tool identifies metabolic clues in colorectal cancer

Metabolite profiles in spinal fluid predict mortality in tuberculous meningitis

Unlocking the secrets of human longevity and healthy aging

Gut bacteria and diet found to affect cancer treatment outcomes

Cysteine depletion triggers rapid weight loss in mice

Blood and urine tests reveal how much ultra-processed food you really eat, study finds

Vitamin D supplements help preserve telomere length in aging adults

Microplastics in ultra-processed foods may fuel mental health risks, experts warn

Exploring the link between microbial balance and aging mechanisms

Gut bacteria and genes jointly shape obesity risk, review reveals hidden links

Cell Painting technology uncovers flavonoids with potential to treat bladder cancer

NIH researchers develop poly-metabolite score to measure ultra-processed food intake

Personalized gene editing corrects fatal infant metabolic disorder in world-first treatment

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?