Metabolism News and Research

Latest Metabolism News and Research

Farxiga approved in the US for the treatment of chronic kidney disease in patients at risk of progression with and without type-2 diabetes

Approval is the most significant advancement in the treatment of chronic kidney disease in more than 20 years. In DAPA-CKD Phase III trial, Farxiga demonstrated unprecedented reduction in the risk of the composite of worsening of renal function, end-stage kidney disease and cardiovascular or renal death.

From AstraZeneca 14 May 2021

Do labels on commercial kefir products report microbial levels correctly?

A recent study in the journal JDS Communications reports the results of an analysis of five brands of kefir on the US market, indicating the need for stricter regulation of this field.

14 May 2021

Phosphatidic acid is a key common substrate for hepatitis C and SARS-CoV-2 replication

A new study, released as a preprint on the bioRxiv* server, focuses on the lipid molecule called phosphatidic acid (PA), showing its crucial role in the replication of this virus, and thus its potential as a target for therapeutic intervention.

13 May 2021

New study may help develop senolytic drugs that target senescent immune cells

In a study recently published in Nature University of Minnesota Medical School researchers found that senescent immune cells are the most dangerous type of senescent cell.

13 May 2021

Measuring metabolic 'fluxes' could help scientists advance new tuberculosis drugs

Mycobacterium tuberculosis is incredible in that it can survive for decades within its human host. It does this by varying its diet to successfully steal nutrients from the human host including immune cells; it is known to acquire and absorb multiple carbon sources from the body during infection.

12 May 2021

Sepsis can cause alterations in the functioning of defense cells that lead to death

An article published in Frontiers in Immunology suggests that sepsis can cause alterations in the functioning of defense cells that persist even after the patient is discharged from hospital.

12 May 2021

Sepsis can cause alterations in the functioning of defense cells that lead to death

An article published in Frontiers in Immunology suggests that sepsis can cause alterations in the functioning of defense cells that persist even after the patient is discharged from hospital.

12 May 2021

Natural products a rich source for novel antiviral compounds

In a recent review in the journal Viruses, researchers look at natural products that can be identified as potential alternative antiviral agents. The reviewers discussed the antiviral activities of several natural products towards DNA and RNA viruses with an analytical approach. The researchers detailed the cellular/viral targets of the active molecules and their impact on the infection and viral replication cycle.

10 May 2021

Normalizing cholesterol metabolism in microglia alleviates chronic neuropathic pain

Chemotherapy can induce a painful peripheral neuropathy (CIPN), a chronic condition and common adverse effect for cancer patients undergoing treatment.

10 May 2021

Complementary medicines for weight loss cannot be justified based on current evidence, review suggests

The first global review of complementary medicines (herbal and dietary supplements) for weight loss in 16 years--combining 121 randomized placebo-controlled trials including nearly 10,000 adults--suggests that their use cannot be justified based on the current evidence.

8 May 2021

Targeted therapies could exploit unique metabolic features of pancreatic cancer cells

Probing the unique biology of human pancreatic cancer cells in a laboratory has yielded unexpected insights of a weakness that can be used against the cells to kill them.

7 May 2021

Researchers identify genetic cause of a rare neurological disorder

In a paper published today in Nature Communications, an international group of collaborators led by researchers at UPMC Children's Hospital of Pittsburgh have identified a genetic cause of a rare neurological disorder marked by developmental delay and loss of coordination, or ataxia.

7 May 2021

Imbalance in gut microbiota could play a key role in progression of inflammatory skin disorder

Findings presented at today’s EADV 2021 Spring Symposium suggest that an imbalance in gut microbiota (dysbiosis), could play a significant role in the progression of inflammatory skin disease, Hidradenitis Suppurativa (HS).

7 May 2021

Microneedles for cancer immunotherapy may lead to minimal invasiveness, side effects

A recent study from the University of Helsinki monitors the breakthrough progresses in the development of microneedles for immunotherapy and discusses the challenges regarding their production.

6 May 2021

Scientists discover fundamental regulation mechanism of proteins

Proteins perform a vast array of functions in the cell of every living organism with critical roles in almost every biological process.

5 May 2021

The FDA expands collaboration with CN Bio to investigate lung-on-a-chip model for inhaled drug evaluation applications

CN Bio today announced the U.S. Food and Drug Administration (FDA) has extended their research collaboration, for a further three years.

From CN Bio 5 May 2021

Certain parts of the innate immune response can be trained in response to HIV

Immunity often calls to mind the adaptive immune response, made up of antibodies and T cells that learn to fight specific pathogens after infection or vaccination.

5 May 2021

Study investigates how Brd4 influences diet-induced obesity

A new study, published in JCI Insight, looks at how Brd4, a regulator of the innate immune response, influences diet-induced obesity.

4 May 2021

Stomach-specific protein plays a key role in the progression of obesity

Scientists believe a stomach-specific protein plays a major role in the progression of obesity, according to new research in Scientific Reports.

4 May 2021

Researchers provide a promising new way to elucidate the brain's health

Researchers from the Center for BrainHealth at The University of Texas at Dallas are investigating a potential new early indicator of the decline toward Alzheimer's disease: measuring the energy metabolism of the living human brain using cutting-edge imaging techniques.

4 May 2021

Metabolism News and Research

Latest Metabolism News and Research

Farxiga approved in the US for the treatment of chronic kidney disease in patients at risk of progression with and without type-2 diabetes

Do labels on commercial kefir products report microbial levels correctly?

Phosphatidic acid is a key common substrate for hepatitis C and SARS-CoV-2 replication

New study may help develop senolytic drugs that target senescent immune cells

Measuring metabolic 'fluxes' could help scientists advance new tuberculosis drugs

Sepsis can cause alterations in the functioning of defense cells that lead to death

Sepsis can cause alterations in the functioning of defense cells that lead to death

Natural products a rich source for novel antiviral compounds

Normalizing cholesterol metabolism in microglia alleviates chronic neuropathic pain

Complementary medicines for weight loss cannot be justified based on current evidence, review suggests

Targeted therapies could exploit unique metabolic features of pancreatic cancer cells

Researchers identify genetic cause of a rare neurological disorder

Imbalance in gut microbiota could play a key role in progression of inflammatory skin disorder

Microneedles for cancer immunotherapy may lead to minimal invasiveness, side effects

Scientists discover fundamental regulation mechanism of proteins

The FDA expands collaboration with CN Bio to investigate lung-on-a-chip model for inhaled drug evaluation applications

Certain parts of the innate immune response can be trained in response to HIV

Study investigates how Brd4 influences diet-induced obesity

Stomach-specific protein plays a key role in the progression of obesity

Researchers provide a promising new way to elucidate the brain's health

Industry Focus eBook - Metabolomics eBook

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Industry Focus eBook - Neurology/Neuroscience - 2nd edition

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Industry Focus eBook - Clinical & Point of Care Diagnostics (1st edition)

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition)

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

The importance of ketones from a clinical and medical perspective