Metabolism News and Research

Latest Metabolism News and Research

Paternal exercise has significant impact on child's lifelong metabolic health

Recent studies have linked development of type 2 diabetes and impaired metabolic health individuals to their parents' poor diet, and there is increasing evidence that fathers play an important role in obesity and metabolic programming of their offspring.

22 Oct 2018

Researchers discover how acne-causing bacteria resist treatment

Researchers in Sweden have discovered how acne-causing bacteria feed off their human hosts. The study, which was performed at KTH Royal Institute of Technology, could make it possible to find effective ways to treat severe acne.

22 Oct 2018

LYNPARZA Phase III SOLO-1 results show improved outcome for patients with advanced BRCA-mutated ovarian cancer

AstraZeneca and Merck & Co., Inc., Kenilworth, N.J., today announced detailed results from the Phase III SOLO-1 trial testing LYNPARZA (olaparib) 300 mg tablets twice-daily as a maintenance treatment for patients with newly diagnosed advanced BRCA-mutated ovarian cancer who were in complete or partial response following 1st-line standard platinum-based chemotherapy.

22 Oct 2018

Study reveals connection between two proteins known to be hyperactive in cancer

A team of researchers at Baylor College of Medicine and Texas Children's Hospital has revealed a connection between mTORC1 and Src, two proteins known to be hyperactive in cancer.

20 Oct 2018

Scientists uncover key regulator of mTORC1 in cancer growth

Scientists have discovered that Src is needed for activation of mTORC1, a major regulator of cellular metabolism, growth and proliferation in cancer.

19 Oct 2018

Weight loss success associated with brain areas involved in self-control

New research suggests that higher-level brain functions have a major role in losing weight. In a study among 24 participants at a weight-loss clinic, those who achieved greatest success in terms of weight loss demonstrated more activity in the brain regions of the lateral prefrontal cortex associated with self-control.

19 Oct 2018

Understanding of metal-free enzymes used by bacteria could lead to new effective antibiotics

Some bacterial pathogens, including those that cause strep throat and pneumonia, are able to create the components necessary to replicate their DNA without the usually required metal ions.

19 Oct 2018

Newly developed synthetic DNA molecule may one day be used as 'vaccine' for prostate cancer

Researchers from City of Hope, a world-renowned comprehensive cancer center and independent biomedical research institution, have developed a synthetic DNA molecule that is programmed to jump-start the immune system to eradicate genetically distinct types of prostate cancer.

19 Oct 2018

UT Southwestern biochemist receives 2019 Breakthrough Prize in Life Sciences for innate immunity discovery

UT Southwestern biochemist Dr. Zhijian "James" Chen today was named winner of the prestigious 2019 Breakthrough Prize in Life Sciences for his discovery of the cGAS enzyme that launches the body's immune defense against infections and cancers.

19 Oct 2018

People with more copies of AMY1 gene digest starchy carbohydrates faster

Found in saliva, the protein enzyme encoded by the AMY1 gene begins the digestive process by breaking down starch when you chew your food.

19 Oct 2018

A new approach identified to control Zika virus, dengue fever

Mosquitoes are the world's deadliest animals, killing thousands of people and causing millions of illnesses each year.

19 Oct 2018

Study finds changes in antiepileptic drug metabolism during different trimesters of pregnancy

During pregnancy, the numerous physiological changes a woman's body undergoes can alter the way medications are metabolized, the rate at which they are cleared, and their overall effectiveness.

17 Oct 2018

Study finds undiagnosed prediabetes in many infertile men

In a study of 744 infertile men, prediabetes was found in 114 (15.4 percent) of participants. Certain factors were linked with prediabetes in the BJU International study, and they might be useful markers for identifying men who could benefit from early preventive interventions to safeguard against the development of diabetes.

17 Oct 2018

Researchers find opportunity to control salt-sensitive hypertension without exercising

Couch potatoes rejoice -- there might be a way to get the blood pressure lowering benefits of exercise in pill form.

16 Oct 2018

Nutritional quality of breakfast linked to cardiovascular and metabolic risk factors in children

Researchers at the Institute for Innovation and Sustainable Development in the Food Chain of the Public University of Navarre have published a piece of research in which they show that the nutritional quality of breakfast is associated with significant cardiovascular and metabolic risk factors in overweight children (even in those who are fit and who do exercise every day).

16 Oct 2018

Yale researchers develop way to attack RNA with small-molecule drugs

Yale researchers have developed a way to target RNA with small-molecule drugs, creating a new method for tapping into a vast number of biological mechanisms critical to metabolism and gene expression.

15 Oct 2018

Endurance exercise training beneficially alters gut microbiota composition

According to recent research, endurance exercise training beneficially modifies gut microbiota composition. After six weeks of training, potentially inflammation causing microbes (Proteobacteria) decreased and microbes that are linked to enhanced metabolism (Akkermansia) increased.

15 Oct 2018

Researchers develop comprehensive molecular atlas of postnatal mouse heart development

Myocardial infarction is one of the most common causes of death in the Western world. Typically, MI is caused by the blockage of a coronary artery by an atherosclerotic plaque: as the oxygen supply of the heart drops, cell death occurs.

15 Oct 2018

Increasing vigorous exercise reduces risk factors of type 2 diabetes, cardiovascular disease in children

Physical exercise can reduce the risk factors of type 2 diabetes and cardiovascular disease even in children, a new study from the University of Eastern Finland shows.

15 Oct 2018

Lab study shows effectiveness of potential therapy for treatment-resistant hypothyroidism

A new "metal-coordinated" drug-delivery technology potentially could be used to supplement the standard therapy for hypothyroidism, which affects nearly 10 million Americans, and many more patients worldwide, according to results of a study published in the journal Thyroid this month.

15 Oct 2018

Metabolism News and Research

Latest Metabolism News and Research

Paternal exercise has significant impact on child's lifelong metabolic health

Researchers discover how acne-causing bacteria resist treatment

LYNPARZA Phase III SOLO-1 results show improved outcome for patients with advanced BRCA-mutated ovarian cancer

Study reveals connection between two proteins known to be hyperactive in cancer

Scientists uncover key regulator of mTORC1 in cancer growth

Weight loss success associated with brain areas involved in self-control

Understanding of metal-free enzymes used by bacteria could lead to new effective antibiotics

Newly developed synthetic DNA molecule may one day be used as 'vaccine' for prostate cancer

UT Southwestern biochemist receives 2019 Breakthrough Prize in Life Sciences for innate immunity discovery

People with more copies of AMY1 gene digest starchy carbohydrates faster

A new approach identified to control Zika virus, dengue fever

Study finds changes in antiepileptic drug metabolism during different trimesters of pregnancy

Study finds undiagnosed prediabetes in many infertile men

Researchers find opportunity to control salt-sensitive hypertension without exercising

Nutritional quality of breakfast linked to cardiovascular and metabolic risk factors in children

Yale researchers develop way to attack RNA with small-molecule drugs

Endurance exercise training beneficially alters gut microbiota composition

Researchers develop comprehensive molecular atlas of postnatal mouse heart development

Increasing vigorous exercise reduces risk factors of type 2 diabetes, cardiovascular disease in children

Lab study shows effectiveness of potential therapy for treatment-resistant hypothyroidism

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