Nervous System News and Research

Latest Nervous System News and Research

Portugal life scientist awarded ERC's Advanced Investigator Grant

Zachary Mainen, coordinator of the Champalimaud Foundation Neuroscience Programme at the IGC, has become one of the most recent winners of the prestigious and highly competitive European Research Council grants, to the value of 2.3 million euro, for a period of five years. This grant, which recognises Mainen's contribution to the Neuroscience field, will be used to elucidate the biological role of the neurotransmitter serotonin.

18 Jan 2010

Findings could pave way for new therapeutic approaches for Friedreich's ataxia

Elevated levels of DNA damage have for the first time been found in the cellular mitochondria and nuclei of patients with the inherited, progressive nervous system disease called Friedreich's ataxia (FRDA), says a multicenter research team led by an expert from the University of Pittsburgh Cancer Institute (UPCI).

18 Jan 2010

Dartmouth researchers to develop and market a drug throughout Asia for treatment of CKD

Thanks in part to more than a decade of preclinical work by Dartmouth researchers, a Japanese biopharmaceutical firm is preparing to develop and market throughout Asia a drug for the treatment of chronic kidney disease (CKD).

18 Jan 2010

IGC scientist wins ERC grant for neuroscience research

18 Jan 2010

New findings may yield novel therapies for chronic neurodegenerative diseases

We all have at one time or another experienced the typical signs of an infection: the fever, the listlessness, the lack of appetite. They are orchestrated by the brain in response to circulating cytokines, the signaling molecules of the immune system. But just how cytokines' reach extends beyond the almost impenetrable blood-brain barrier has been the topic of much dispute.

18 Jan 2010

Study evaluates potential treatments for daytime sleepiness in head-injury patients

Local patients are being sought for a national clinical research study currently investigating a study medication for people who have had a head injury, concussion or bump on the head and feel sleepy or tired during the day.

13 Jan 2010

Findings may pave way for significant advancements in cochlear implant technology for hearing loss

Loss of spiral ganglion neurons or hair cells in the inner ear is the leading cause of congenital and acquired hearing impairment. Researchers at the University of California, San Diego, School of Medicine and the National Institutes of Health found that Sox2, a protein that regulates stem cell formation, is involved in spiral ganglion neuron development. The study was published in the January 13 issue of the Journal of Neuroscience.

13 Jan 2010

New clinical study: CeNeRx BioPharma's CXB722 has potential as novel anxiolytic

CeNeRx BioPharma, Inc., a clinical stage company developing and commercializing innovative treatments for diseases of the central nervous system, today reported that a new clinical study shows that its investigational compound CXB722 has potential as a novel anxiolytic, demonstrating a significant effect on both endocrine and cardiovascular biomarkers associated with stress.

13 Jan 2010

moksha8 receives approval to import and use peramivir in patients with H1N1 influenza A in Mexico

moksha8 and BioCryst today announced that moksha8 has been granted approval from COFEPRIS (The Federal Commission for the Protection against Sanitary Risk) in Mexico for the importation and use of peramivir in patients with influenza associated with the 2009 H1N1 influenza A strain.

13 Jan 2010

MedGenesis Therapeutix enters into license agreement with Amgen

MedGenesis Therapeutix Inc. ("MedGenesis"), a biopharmaceutical company developing and commercializing innovative treatments for patients with serious central nervous system (CNS) diseases, announced today that it has successfully entered into an agreement with Amgen Inc. ("Amgen"), granting MedGenesis an exclusive, worldwide license for glial cell line-derived neurotrophic factor (GDNF) protein in CNS and non-CNS indications, subject to the rights of a co-exclusive licensee for CNS indications in certain countries, as further described below.

12 Jan 2010

Reducing DA dosage causes acute withdrawal symptoms in Parkinson's patients

New research has shown that reducing the dosage of dopamine agonist (DA) drugs, a mainstay treatment for Parkinson's disease (PD), sometimes causes acute withdrawal symptoms similar to those reported by cocaine addicts -- including anxiety, panic attacks, depression, sweating, nausea, generalized pain, fatigue, dizziness and drug cravings. These symptoms can be severe, and are not alleviated by other PD medications.

12 Jan 2010

PET-CT imaging appears to detect cancer in patients with neurologic complications

A combined positron emission tomography-computed tomography (PET-CT) scan of the whole body appears to detect cancer in individuals with related neurologic complications more accurately than some other commonly used tests, according to a report posted online today that will appear in the March print issue of Archives of Neurology, one of the JAMA/Archives journals.

12 Jan 2010

Positive results from KemPharm's KP106 Phase 1 clinical trial for ADHD

KemPharm, Inc. today announced positive results from a Phase 1 clinical trial of KP106, its novel prodrug for attention-deficit hyperactivity disorder (ADHD). KP106, a new chemical entity (NCE) composed of the active pharmaceutical compound d-amphetamine and a ligand, was created using KemPharm’s proprietary Ligand Activated Therapy (LAT) prodrug approach.

12 Jan 2010

Sangamo BioSciences initiates two new clinical trials of ZFP Therapeutics

Sangamo BioSciences, Inc. announced the initiation of two new clinical trials of ZFP Therapeutics, a Phase 2b study in diabetic neuropathy (DN) and a Phase 1 trial in glioblastoma, as well as the renewal of $3.0 million in funding for the Phase 2b trial by the Juvenile Diabetes Research Foundation International (JDRF).

11 Jan 2010

Targacept signs collaboration and license agreement with AstraZeneca

Targacept, Inc., a clinical-stage biopharmaceutical company developing a new class of drugs known as NNR Therapeutics™, today announced that its collaboration and license agreement with AstraZeneca for the global development and commercialization of TC-5214 for major depressive disorder (MDD) has become effective as a result of early termination of the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act.

11 Jan 2010

BIDMC scientists identify new pathway to address the problem of photophobia during migraines

Ask anyone who suffers from migraine headaches what they do when they're having an attack, and you're likely to hear "go into a dark room." And although it's long been known that light makes migraines worse, the reason why has been unclear.

11 Jan 2010

Gene therapy may help correct molecular flaws that cause brain disease

Neuroscientists have forged an unlikely molecular union as part of their fight against diseases of the brain and nervous system.

9 Jan 2010

Luna Innovations extends its development and supply agreement with Intuitive Surgical

Luna Innovations Incorporated announced today that it will be extending its development and supply agreement with Intuitive Surgical, Inc. (NASDAQ: ISRG) to continue integrating Luna’s shape sensing technology into Intuitive’s products.

8 Jan 2010

Chinese researchers become the world's fifth most prolific contributors to regenerative medicine

Chinese researchers have become the world's fifth most prolific contributors to peer-reviewed scientific literature on clock-reversing regenerative medicine even as a skeptical international research community condemns the practice of Chinese clinics administering unproven stem cell therapies to domestic and foreign patients.

8 Jan 2010

Scientists identify gene underlying a disease that causes temporary paralysis of skeletal muscle

Scientists have identified a gene underlying a disease that causes temporary paralysis of skeletal muscle. The finding, they say, illustrates how investigations of rare genetic diseases can drive insights into more common ones.

8 Jan 2010

Nervous System News and Research

Latest Nervous System News and Research

Portugal life scientist awarded ERC's Advanced Investigator Grant

Findings could pave way for new therapeutic approaches for Friedreich's ataxia

Dartmouth researchers to develop and market a drug throughout Asia for treatment of CKD

IGC scientist wins ERC grant for neuroscience research

New findings may yield novel therapies for chronic neurodegenerative diseases

Study evaluates potential treatments for daytime sleepiness in head-injury patients

Findings may pave way for significant advancements in cochlear implant technology for hearing loss

New clinical study: CeNeRx BioPharma's CXB722 has potential as novel anxiolytic

moksha8 receives approval to import and use peramivir in patients with H1N1 influenza A in Mexico

MedGenesis Therapeutix enters into license agreement with Amgen

Reducing DA dosage causes acute withdrawal symptoms in Parkinson's patients

PET-CT imaging appears to detect cancer in patients with neurologic complications

Positive results from KemPharm's KP106 Phase 1 clinical trial for ADHD

Sangamo BioSciences initiates two new clinical trials of ZFP Therapeutics

Targacept signs collaboration and license agreement with AstraZeneca

BIDMC scientists identify new pathway to address the problem of photophobia during migraines

Gene therapy may help correct molecular flaws that cause brain disease

Luna Innovations extends its development and supply agreement with Intuitive Surgical

Chinese researchers become the world's fifth most prolific contributors to regenerative medicine

Scientists identify gene underlying a disease that causes temporary paralysis of skeletal muscle

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Nervous System News and Research

Latest Nervous System News and Research

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Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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