Nervous System News and Research

Latest Nervous System News and Research

Combination of advanced techniques in robotics and neuroscience shows promise for stroke patients

Bioengineers have taken a small step toward improving physical recovery in stroke patients by showing that a key feature of how limb motion is encoded in the nervous system plays a crucial role in how new motor skills are learned.

8 Jan 2010

New genetic findings may lead to better interventional therapies for obsessive compulsive disorders

A collaboration between the University of Massachusetts Medical School, the Cummings School of Veterinary Medicine at Tufts University and the Broad Institute at the Massachusetts Institute of Technology has identified a genetic locus on canine chromosome 7 which coincides with an increased risk of obsessive compulsive disorder (OCD) susceptibility.

7 Jan 2010

Mutations in genome regulation machinery identified in clear cell renal cell carcinoma

In a new study, scientists have searched for mutations in the gene regions of more than 100 kidney cancer samples, the largest number of samples from a single tumour type to be sequenced to date.

7 Jan 2010

Researchers identify new approach to eliminate side effects of drugs

Researchers at the Stanford University School of Medicine have taken an early step toward identifying a new approach to drug discovery that may eventually yield drugs with fewer side effects.

7 Jan 2010

Diffusion tensor imaging detects signs of Alzheimer's disease

A new type of brain scan, called diffusion tensor imaging (DTI), appears to be better at detecting whether a person with memory loss might have brain changes of Alzheimer's disease, according to a new study published in the January 6, 2010, online issue of Neurology®, the medical journal of the American Academy of Neurology.

7 Jan 2010

Phase II clinical trial of Gilead Sciences' elvitegravir, GS 9350 and Truvada meets primary objective

Gilead Sciences, Inc. today announced that a Phase II clinical trial of its investigational integrase inhibitor-based, once-daily, fixed-dose “Quad” regimen of elvitegravir, GS 9350 and Truvada® (emtricitabine and tenofovir disoproxil fumarate) for the treatment of HIV-1 infection met its primary objective.

7 Jan 2010

EnVivo Pharmaceuticals announces initiation and dosing of patients in Phase 2b study of EVP-6124

EnVivo Pharmaceuticals today announced the initiation and dosing of patients in a Phase 2b study of its EVP-6124 compound, a selective alpha-7 nicotinic agonist in patients with schizophrenia. EnVivo is conducting the multi-center, dose ranging, placebo controlled, three-month study in the U.S. and Europe.

6 Jan 2010

WPI researchers lay groundwork for new generation of advanced prosthetic limbs

The conflicts in Iraq and Afghanistan have left a terrible legacy: more than 1,200 returning American soldiers have lost one or more limbs. To address this growing national need, researchers at Worcester Polytechnic Institute (WPI) are laying the groundwork for a new generation of advanced prosthetic limbs that will be fully integrated with the body and nervous system.

5 Jan 2010

Scientists identify genetic marker to diagnose DFTD

An international team of scientists led by a Cold Spring Harbor Laboratory (CSHL) investigator has discovered that the deadly facial tumors decimating Australia's Tasmanian devil population probably originated in Schwann cells, a type of tissue that cushions and protects nerve fibers.

4 Jan 2010

Erectile dysfunction linked to RLS in older men

A study in the Jan. 1 issue of the journal Sleep shows that erectile dysfunction was more common in older men with restless leg syndrome (RLS) than in those without RLS, and the magnitude of this association increased with a higher frequency of RLS symptoms.

3 Jan 2010

TENS therapy is not effective against chronic low-back pain

A new guideline issued by the American Academy of Neurology finds that transcutaneous electric nerve stimulation (TENS), a widely used pain therapy involving a portable device, is not recommended to treat chronic low-back pain that has persisted for three months or longer because research shows it is not effective.

31 Dec 2009

FDA accepts NDA review for new anticonvulsant drug

The U.S. Food and Drug Administration (FDA) has accepted for review the New Drug Application (NDA) seeking marketing approval for Retigabine. In addition, the European Medicines Agency (EMEA) confirmed on November 17, 2009 that the MAA (Marketing Authorization Application) was successfully validated thus enabling the MAA review to commence.

30 Dec 2009

NeurAxon closes the sale of $8.75 million of unsecured subordinated convertible debentures

NeurAxon, Inc., a development-stage pharmaceutical company that is designing and developing next-generation pain therapeutics targeting neuronal nitric oxide synthase (nNOS), today announced that it has closed the sale of approximately $8.75 million of unsecured subordinated 2.0% convertible debentures that are convertible under specified circumstances into existing class B preferred shares.

29 Dec 2009

Emerald BioStructures engineers new allosteric small molecule modulators of the PDE4 enzyme

Emerald BioStructures (formerly deCODE biostructures) announced today a publication in the December 27, 2009 advance online issue of Nature Biotechnology, detailing the application of structure-based drug design (SBDD) to engineer new allosteric small molecule modulators of the enzyme phosphodiesterase-4 (PDE4), with reduced side effects. According to the paper, the researchers established the structural basis of PDE4 regulation through crystal structures of the PDE4 regulatory domain in contact with small molecules.

29 Dec 2009

Study explains how semaphorin gene regulates synapse formation

By combining a research technique that dates back 136 years with modern molecular genetics, a Johns Hopkins neuroscientist has been able to see how a mammal's brain shrewdly revisits and reuses the same molecular cues to control the complex design of its circuits.

29 Dec 2009

Defects in protein-secretion machinery linked to neural tube closure

Spinal cord disorders like spina bifida arise during early development when future spinal cord cells growing in a flat layer fail to roll up into a tube. In the Dec. 6 issue of Nature Cell Biology, researchers from the Johns Hopkins University School of Medicine team with colleagues at the University of California, Berkeley to report a never-before known link between protein transport and mouse spinal cord development, a discovery that opens new doors for research on all spinal defects.

29 Dec 2009

Nutrient-rich foods for weight loss

For the majority of Americans who are unhappy with their weight at any given moment, the New Year brings mixed emotions: the renewed resolution to shed pounds and the challenge of learning how to eat right to reach those goals.

29 Dec 2009

Nanoscaffolds could play a central role in tissue and organ reconstruction

Researchers from the University of Hong Kong and the Massachusetts Institute of Technology have published a study in the current issue of Cell Transplantation (18:9), now freely available on line at http://www.ingentaconnect.com/content/cog/ct, that explores ways to successfully keep stem cells "forever young" during implantation by slowing their growth, differentiation and proliferation.

28 Dec 2009

Publication validates company's structure-based approach for addressing undruggable targets

28 Dec 2009

Test tube experiments show slight changes in protein chemistry can eliminate Huntington's disease in mice

In Huntington's disease, a mutated protein in the body becomes toxic to brain cells. Recent studies have demonstrated that a small region adjacent to the mutated segment plays a major role in the toxicity. Two new studies supported by the National Institutes of Health show that very slight changes to this region can eliminate signs of Huntington's disease in mice.

28 Dec 2009

Nervous System News and Research

Latest Nervous System News and Research

Combination of advanced techniques in robotics and neuroscience shows promise for stroke patients

New genetic findings may lead to better interventional therapies for obsessive compulsive disorders

Mutations in genome regulation machinery identified in clear cell renal cell carcinoma

Researchers identify new approach to eliminate side effects of drugs

Diffusion tensor imaging detects signs of Alzheimer's disease

Phase II clinical trial of Gilead Sciences' elvitegravir, GS 9350 and Truvada meets primary objective

EnVivo Pharmaceuticals announces initiation and dosing of patients in Phase 2b study of EVP-6124

WPI researchers lay groundwork for new generation of advanced prosthetic limbs

Scientists identify genetic marker to diagnose DFTD

Erectile dysfunction linked to RLS in older men

TENS therapy is not effective against chronic low-back pain

FDA accepts NDA review for new anticonvulsant drug

NeurAxon closes the sale of $8.75 million of unsecured subordinated convertible debentures

Emerald BioStructures engineers new allosteric small molecule modulators of the PDE4 enzyme

Study explains how semaphorin gene regulates synapse formation

Defects in protein-secretion machinery linked to neural tube closure

Nutrient-rich foods for weight loss

Nanoscaffolds could play a central role in tissue and organ reconstruction

Publication validates company's structure-based approach for addressing undruggable targets

Test tube experiments show slight changes in protein chemistry can eliminate Huntington's disease in mice

Everything you need to know about epilepsy eBook

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

Nervous System News and Research

Latest Nervous System News and Research

Everything you need to know about epilepsy eBook

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

Newsletters you may be interested in