Severe Acute Respiratory Syndrome

Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by a coronavirus, called SARS-associated coronavirus (SARS-CoV). SARS was first reported in Asia in February 2003. Over the next few months, the illness spread to more than two dozen countries in North America, South America, Europe, and Asia before the SARS global outbreak of 2003 was contained.

SARS or Severe Acute Respiratory Syndrome is a viral respiratory illness caused by a coronavirus - the SARS associated coronavirus (SARS-CoV) - which can be life-threatening.

How SARS is Spread

SARS, Treatment, Control and Tests

SARS: Tips for Travellers

E406W mutation on SARS-CoV-2 RBD escapes monoclonal antibody cocktail-mediated neutralization

Researchers look to better understand the molecular basis of E406W-mediated escape from the REGEN-COV cocktail and cilgavimab.

28 Jan 2022

Intranasal interferon-λ treatment protects mice against SARS-CoV-2 Beta and Omicron variants

Researchers investigate the possible efficacy of IFN-λ in the context of SARS-CoV-2 infection in mice.

28 Jan 2022

Early-stage alveolar epithelial cell necrosis linked to COVID-19-induced acute respiratory distress syndrome

A new study analyzed whether alveolar epithelial cell necrosis at an early stage SARS-CoV-2 infection and subsequent releases of damage-associated molecular patterns could aggravate COVID-19-associated acute respiratory distress syndrome.

27 Jan 2022

Scientists identify immunogens that can elicit antibody responses against multiple SARS-CoV-2 variants

In a new study, researchers identified conserved sites in the SARS-CoV-2 spike protein using structural and sequence data, and then combined the results with existing deep mutational scanning data to design six antigens that can offer protection against significant immune escape mutations in the SARS-CoV-2 receptor-binding domain.

27 Jan 2022

SARS-CoV-2 mutations and their impact on spike protein-specific T lymphocytes

New research assesses the impact of mutations in SARS-CoV-2 variants of concern (VOCs) on the T lymphocytes, specifically to the spike (S) protein of SARS-CoV-2.

27 Jan 2022

Effects of multi-nutrient supplementation on COVID-19 severity in elderly patients

In a new study, researchers analyzed the effects of multi-nutrient supplementation on SARS-CoV-2 vaccine efficacy and the overall improvement of respiratory and muscle function in elderly COVID-19 patients.

27 Jan 2022

Targeting CHI3L1 inhibits SARS-CoV-2 variants, including Delta and Omicron

Researchers show that the CHI3L1 inhibitors reduce epithelial cell infection by SARS-CoV-2 VOC pseudovirus moieties.

27 Jan 2022

Significance of metabolic parameters in COVID-19 prognosis

In a new study, researchers evaluated the significance of metabolic parameters in determining COVID-19 prognosis.

27 Jan 2022

Impact of full vaccination with booster doses during periods of different SARS-CoV-2 variant emergence and dominance in the United States

This study aimed to assess the impact of full vaccination with additional and booster doses.

27 Jan 2022

Impact of SARS-CoV-2 testing behavior on observational studies of vaccine efficiency

A new study investigated the differences in SARS-CoV-2 testing behavior exhibited by vaccinated and unvaccinated individuals.

27 Jan 2022

Evaluating the effectiveness of vaccination on the case fatality rate for COVID-19 infection

A recent study was published where CFR was assessed for COVID-19 vaccine effectivity

27 Jan 2022

Study suggests enhanced phosphorylation and increased abundance of SARS-CoV-2 nucleocapsid protein provide selective advantage

Researchers have been investigating the phosphorylation of the nucleocapsid protein.

27 Jan 2022

Risk of long COVID-19 predicted by immunoglobulin signature

In a new study published in the journal Nature Communications, scientists studied COVID-19 patients and found that the immunoglobulin (Ig) signature can predict the risk of PACS independently of the time point of blood sampling.

27 Jan 2022

Targeting SARS-CoV-2 M protein may help ease severity of COVID-19

A new study, published on the medRxiv preprint server, focused on the production of human CD4+ T cell lines (TCLs), reactive to either S or M protein, and analyzed if the S and M structural proteins had intrinsic differences in driving antigen-specific CD4+ T cell responses.

27 Jan 2022

Omicron RBD mutations increase ACE2 binding and reduce antibody sensitivity

In a study conducted at the Florida International University, USA, scientists have investigated the impact of spike receptor-binding domain (RBD) mutations of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) omicron variant on its interaction with human angiotensin-converting enzyme 2 (ACE2).

26 Jan 2022

Recipients of inactivated COVID-19 vaccine (CoronaVac) can be successfully boosted with different vaccines

In the recently published study in The Lancet, first-authored by Dr. Sue Ann Costa Clemens from the University of Oxford in the United Kingdom and the University of Siena in Italy, a comprehensive analysis has been pursued on the immunogenicity and safety of both homologous and heterologous boosting after receiving the inactivated vaccine CoronaVac.

26 Jan 2022

Severe Acute Respiratory Syndrome

Overview

How SARS is Spread

SARS, Treatment, Control and Tests

SARS: Tips for Travellers

Latest Severe Acute Respiratory Syndrome News and Research

E406W mutation on SARS-CoV-2 RBD escapes monoclonal antibody cocktail-mediated neutralization

Intranasal interferon-λ treatment protects mice against SARS-CoV-2 Beta and Omicron variants

Early-stage alveolar epithelial cell necrosis linked to COVID-19-induced acute respiratory distress syndrome

Scientists identify immunogens that can elicit antibody responses against multiple SARS-CoV-2 variants

SARS-CoV-2 mutations and their impact on spike protein-specific T lymphocytes

Effects of multi-nutrient supplementation on COVID-19 severity in elderly patients

Targeting CHI3L1 inhibits SARS-CoV-2 variants, including Delta and Omicron

Significance of metabolic parameters in COVID-19 prognosis

Impact of full vaccination with booster doses during periods of different SARS-CoV-2 variant emergence and dominance in the United States

Impact of SARS-CoV-2 testing behavior on observational studies of vaccine efficiency

Evaluating the effectiveness of vaccination on the case fatality rate for COVID-19 infection

Study suggests enhanced phosphorylation and increased abundance of SARS-CoV-2 nucleocapsid protein provide selective advantage

Risk of long COVID-19 predicted by immunoglobulin signature

Targeting SARS-CoV-2 M protein may help ease severity of COVID-19

Omicron RBD mutations increase ACE2 binding and reduce antibody sensitivity

Recipients of inactivated COVID-19 vaccine (CoronaVac) can be successfully boosted with different vaccines

Urinary proteomic COV50 marker accurately predicts adverse COVID-19 outcomes

T-cell apoptosis linked to poor prognosis among COVID-19 patients

Study shows enduring T-cell immunity up to at least 1-year after SARS-CoV-2 infection

New research on SARS-CoV-2 Omicron and care home residents

Predicting pregnancy health and preeclampsia risk with blood RNA sequencing

Novel gene therapy for diseased muscle fiber repair

PFAS found in high levels in anti-fogging sprays

Severe Acute Respiratory Syndrome

Overview

Latest Severe Acute Respiratory Syndrome News and Research

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