Thalassemia

Thalassemia is a group of genetic blood disorders that affect approximately 1,000 individuals in the United States. The most severe of these disorders is Cooley's Anemia.

People with thalassemia have a genetic defect of their red blood cells that affects the cells' ability to produce normal hemoglobin. Red blood cells use hemoglobin to carry oxygen to tissues. As a result of the defect, most forms of thalassemia produce a chronic, lifelong anemia that begins in early childhood and often must be treated with frequent transfusions.
What is Thalassemia?

Beta thalassemia describes a condition of the blood characterized by abnormal hemoglobin in the red blood cells. This abnormal hemoglobin is reduced in its capacity to transport oxygen around the body, which leads to anemia, fatigue, weakness and shortness of breath.

Read More

Overview

Feature Articles

Latest Thalassemia News and Research

Toward a transformative therapy for sickle cell patients

Toward a transformative therapy for sickle cell patients

PNA-based gene editing technique can advance gene discovery

PNA-based gene editing technique can advance gene discovery

Research provides a new cornerstone of malaria's evolution with humans

Research provides a new cornerstone of malaria's evolution with humans

Combined liver-cytokine humanization enhances human red blood cell production and survival

Combined liver-cytokine humanization enhances human red blood cell production and survival

Study: TALEN is five times more efficient than CRISPR-Cas9 in tightly packed DNA

Study: TALEN is five times more efficient than CRISPR-Cas9 in tightly packed DNA

New taxonomic classification of non-skeletal rare congenital disorders with impact on bone physiology

New taxonomic classification of non-skeletal rare congenital disorders with impact on bone physiology

Researchers develop telomerase gene therapy for treating different pathologies

Researchers develop telomerase gene therapy for treating different pathologies

Majority of U.S. COVID-19 fatalities had underlying medical conditions

Majority of U.S. COVID-19 fatalities had underlying medical conditions

Umbilical cord blood safely and effectively treats children with rare genetic disorders

Umbilical cord blood safely and effectively treats children with rare genetic disorders

Impact of COVID-19 on pregnancy and breastfed infants

Impact of COVID-19 on pregnancy and breastfed infants

Rice University wins prestigious grant to develop new therapies for sickle cell disease

Rice University wins prestigious grant to develop new therapies for sickle cell disease

Ancient DNA analysis provides insight into genetic history of Sardinia

Ancient DNA analysis provides insight into genetic history of Sardinia

Horizon Discovery to offer novel base editing technology for clinical research

Horizon Discovery to offer novel base editing technology for clinical research

Fresh red blood cell transfusions are no more beneficial than older ones to critically ill children

Fresh red blood cell transfusions are no more beneficial than older ones to critically ill children

Mystery surrounds gene edited babies one year on

Mystery surrounds gene edited babies one year on

Pioneering CRISPR therapy leaves two patients free of blood disease symptoms

Pioneering CRISPR therapy leaves two patients free of blood disease symptoms

Deterministic mechanoporation of cells en masse to cure cancer

Deterministic mechanoporation of cells en masse to cure cancer

Carnegie Mellon and Yale win NIH grant to advance gene editing technique

Carnegie Mellon and Yale win NIH grant to advance gene editing technique

Researchers make breakthrough in gene therapy for sickle cell disease

Researchers make breakthrough in gene therapy for sickle cell disease

Genetic engineering could open possibilities for patients with Parkinson’s disease

Genetic engineering could open possibilities for patients with Parkinson’s disease