Thalassemia

Thalassemia is a group of genetic blood disorders that affect approximately 1,000 individuals in the United States. The most severe of these disorders is Cooley's Anemia.

People with thalassemia have a genetic defect of their red blood cells that affects the cells' ability to produce normal hemoglobin. Red blood cells use hemoglobin to carry oxygen to tissues. As a result of the defect, most forms of thalassemia produce a chronic, lifelong anemia that begins in early childhood and often must be treated with frequent transfusions.
What is Thalassemia?

Beta thalassemia describes a condition of the blood characterized by abnormal hemoglobin in the red blood cells. This abnormal hemoglobin is reduced in its capacity to transport oxygen around the body, which leads to anemia, fatigue, weakness and shortness of breath.

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Latest Thalassemia News and Research

Majority of U.S. COVID-19 fatalities had underlying medical conditions

Majority of U.S. COVID-19 fatalities had underlying medical conditions

Umbilical cord blood safely and effectively treats children with rare genetic disorders

Umbilical cord blood safely and effectively treats children with rare genetic disorders

Impact of COVID-19 on pregnancy and breastfed infants

Impact of COVID-19 on pregnancy and breastfed infants

Rice University wins prestigious grant to develop new therapies for sickle cell disease

Rice University wins prestigious grant to develop new therapies for sickle cell disease

Ancient DNA analysis provides insight into genetic history of Sardinia

Ancient DNA analysis provides insight into genetic history of Sardinia

Horizon Discovery to offer novel base editing technology for clinical research

Horizon Discovery to offer novel base editing technology for clinical research

Fresh red blood cell transfusions are no more beneficial than older ones to critically ill children

Fresh red blood cell transfusions are no more beneficial than older ones to critically ill children

Mystery surrounds gene edited babies one year on

Mystery surrounds gene edited babies one year on

Pioneering CRISPR therapy leaves two patients free of blood disease symptoms

Pioneering CRISPR therapy leaves two patients free of blood disease symptoms

Deterministic mechanoporation of cells en masse to cure cancer

Deterministic mechanoporation of cells en masse to cure cancer

Carnegie Mellon and Yale win NIH grant to advance gene editing technique

Carnegie Mellon and Yale win NIH grant to advance gene editing technique

Researchers make breakthrough in gene therapy for sickle cell disease

Researchers make breakthrough in gene therapy for sickle cell disease

Genetic engineering could open possibilities for patients with Parkinson’s disease

Genetic engineering could open possibilities for patients with Parkinson’s disease

First ever American gene-editing treatment using CRISPR for genetic disease

First ever American gene-editing treatment using CRISPR for genetic disease

Better education and communication critical for increasing blood donation among minorities

Better education and communication critical for increasing blood donation among minorities

More screening and new treatments needed for sickle cell disease

More screening and new treatments needed for sickle cell disease

Scientists use gold nanoparticles to edit genes tied to HIV, inherited blood disorders

Scientists use gold nanoparticles to edit genes tied to HIV, inherited blood disorders

Study compares effectiveness and cost of gene therapy and HSCT in major beta-thalassemia

Study compares effectiveness and cost of gene therapy and HSCT in major beta-thalassemia

New gene therapy cures babies with fatal 'Bubble Boy' disease

New gene therapy cures babies with fatal 'Bubble Boy' disease

Researchers develop new strategy to treat sickle cell disease and beta thalassemia

Researchers develop new strategy to treat sickle cell disease and beta thalassemia