Contains the active ingredient methyldopa (as sesquihydrate)
Consumer Medicine Information
What is in this leaflet
This leaflet answers some common questions about Hydopa.
It does not contain all the available information. It does not take the place of talking
to your doctor or pharmacist.
All medicines have benefits and risks. Your doctor has weighed the risks of you taking
Hydopa against the benefits they expect it will have for you.
If you have any concerns about taking this medicine, ask your doctor or pharmacist.
Keep this leaflet with the medicine.
You may need to read it again.
What Hydopa is used for
Hydopa is used to lower high blood pressure, also called hypertension.
Everyone had blood pressure. This pressure helps get your blood all around your body.
Your blood pressure may be different at different times of the day, depending on how
busy or worried you are. You have hypertension (high blood pressure) when your blood
pressure stays higher than is needed, even when you are calm and relaxed.
There are usually no symptoms of hypertension. The only way of knowing that you have
hypertension is to have your blood pressure checked on a regular basis. If high blood
pressure is not treated it can lead to serious health problems. You may feel fine
and have no symptoms, but eventually hypertension can cause stroke, heart disease
and kidney failure. Hydopa helps to lower your blood pressure.
Hydopa works by controlling impulses along certain nerve pathways and as a result,
widens blood vessels so that blood passes through them more easily. This helps to
lower blood pressure.
Ask your doctor if you have any questions about why this medicine has been prescribed
Your doctor may have prescribed it for another reason.
There is no evidence that Hydopa is addictive.
Hydopa is available only with a doctor's prescription.
Before you take Hydopa
When you must not take it
Do not take Hydopa if you have an allergy to:
any medicine containing methyldopa (as sesquihydrate) (e.g. Aldomet)
any of the ingredients listed at the end of this leaflet.
Do not take Hydopa if you:
currently have liver disease (e.g. hepatitis or cirrhosis.
Have hepatitis, cirrhosis, or certain liver diseases.
Do not take Hydopa if you are taking a medicine called a monoamine oxidase inhibitor
MAOIs are used to treat depression and Parkinson's disease. Some examples of MAOIs
include phenelzine, tranylcypromine and selegiline.
Ask your doctor or pharmacist if you are not sure whether you are taking one of these
Do not take Hydopa if the expiry date printed on the pack has passed.
If you take this medicine after the expiry date, it may not work as well. Do not take
Hydopa if the packaging shows signs of tampering or the tablets do not look quite
If you are not sure whether you should start taking Hydopa, talk to your doctor.
Before you start to take it
Tell your doctor if you have allergies to any other medicines, foods, preservatives
Tell your doctor if you have or have had any of the following medical conditions:
Angina (chest pain)
Tell your doctor if you have or are suspected of having phaeochromocytoma (a rare
tumour of the adrenal gland).
Tell your doctor if you are undergoing dialysis (a procedure used to remove waste
products from the blood of a person with kidney failure).
Tell your doctor if you are pregnant or plan to become pregnant or are breast-feeding.
Your doctor can discuss with you the risks and benefits involved.
Hydopa passes into breast milk. Your doctor will discuss the risks and benefits of
taking Hydopa when breastfeeding.
Your doctor may want to take special care if you have any of these conditions.
If you have not told your doctor about any of the above, tell them before you start
Taking other medicines
Tell your doctor or pharmacist if you are taking any other medicines, including any
that you get without a prescription from your pharmacy, supermarket or health food
Some medicines may be affected by Hydopa or may affect how well it works. These include:
other medicines used to treat high blood pressure
lithium, a medicine used to treat mood swings and some types of depression
iron supplements and multivitamins containing iron.
You may need different amounts of your medicine or you may need to take different
Do not take Hydopa if you are taking a MAOI (e.g. moclobemide, phenelzine and tranylcypromine)
Your doctor can tell you what to do if you are taking any of these medicines.
If you are not sure of whether you are taking any of these medicines, check your
doctor or pharmacist.
Your doctor and pharmacist have more information on medicines to be careful with or
avoid while taking Hydopa.
If you do not understand the instructions on the box/bottle, ask your doctor or pharmacist
Your doctor and pharmacist have more information on medicines to be careful with or
avoid while taking this medicine.
How to take Hydopa
Follow all directions given to you by your doctor or pharmacist carefully.
They may differ from the information contained in this leaflet.
If you do not understand the instructions on the bottle, ask your doctor or pharmacist
How much to take
The dose varies from person to person.
This depends on your condition and whether you are taking any other medicines.
Your doctor will tell you how many tablets you need to take each day and when to take
How to take it
Swallow the tablets whole with a glass of water.
When to take it
Take your medicine at about the same time each day, unless your doctor tells you otherwise.
If you are taking it twice a day, take the tablets at breakfast time and dinner time
- that is about 12 hours apart.
If you are taking it three times a day, take the tablets about 8 hours apart.
Taking it at the same time each day will have the best effect on your blood pressure.
It will also help you remember when to take it.
Hydopa can be taken with or without food.
How long to take it
Keep taking Hydopa for as long as your doctor recommends.
Hydopa helps control high blood pressure but does not cure it. To properly control
your condition, Hydopa must be taken every day on a long-term basis.
If you forget to take it
If it is almost time for your next dose, skip the dose you missed and take your next
dose when you are meant to.
Otherwise, take the missed dose as soon as you remember, and then go back to taking
your tablets as you would normally.
Do not take a double dose to make up for the dose you missed.
If you are not sure what to do, ask your doctor or pharmacist.
If you have trouble remembering to take your medicine, ask your pharmacist for some
If you take too much (overdose)
Immediately telephone your doctor, or the Poisons Information Centre (telephone 13
11 26), or go to Accident and Emergency at the nearest hospital, if you think you
or anyone else may have taken too much Hydopa. Do this even if there are no signs
of discomfort or poisoning.
You may need urgent medical attention.
If you take too much Hydopa, you may feel dizzy, lightheaded, drowsy or you may faint.
You may also experience nausea (feeling sick), vomiting, constipation, diarrhoea,
gas/wind in the bowel or develop a bloated stomach.
While you are using Hydopa
Things you must do
If you are about to be started on any new medicine, remind your doctor and pharmacist
that you are taking Hydopa.
Tell any other doctors, dentists and pharmacists who treat you that you are taking
If you are going to have surgery, tell the surgeon or anaesthetist that you are taking
It may affect other medicines used during surgery.
If you need to have surgery that requires a general anaesthetic, tell your doctor
or dentist that you are taking Hydopa. Your blood pressure may drop suddenly.
If you feel light-headed, dizzy or faint, get up slowly when getting out of bed or
You may feel light-headed or dizzy when you begin to take Hydopa or if the dose is
increased. This is because your blood pressure is falling suddenly. Standing up slowly,
especially when you get up from bed or sitting, will help your body get used to the
change in position and blood pressure. The problem usually goes away after the first
If you need to have any blood or urine tests, tell your doctor that you are taking
Hydopa may interfere with the results of some blood and urine tests.
If you going to have a blood transfusion, tell your doctor you are taking Hydopa or
have taken it in the past few months.
Hydopa may interfere with the tests used to decide which blood group you receive.
If you develop a fever, tell your doctor.
Your doctor may ask you to have blood tests to make sure that Hydopa is not affecting
your liver or blood.
Make sure you drink enough water during exercise and hot weather when you are taking
Hydopa, especially if you sweat a lot.
If you do not drink enough water while taking it, you may faint or feel lightheaded
or sick. This is because your body doesn't have enough fluid and your blood pressure
is low. If you continue to feel unwell, tell your doctor.
Since Hydopa is meant to be taken regularly, keep a continuous supply of medicine
so you don't run out, especially over weekends or on holidays.
Have your blood pressure checked regularly when your doctor says to make sure Hydopa
Visit your doctor regularly so they can check on your progress.
Your doctor may want to check your liver function and blood count, especially within
the first 12 weeks of starting Hydopa.
If you become pregnant while taking this medicine, tell your doctor immediately.
Things you must not do
Do not take Hydopa to treat any other complaints unless your doctor tells you to.
Do not give your medicine to anyone else, even if they have the same condition as
Do not stop taking your medicine or lower the dosage without checking with your doctor.
Things to be careful of
Be careful driving or operating machinery until you know how Hydopa affects you.
This medicine may cause cause drowsiness, dizziness or lightheadedness in some people,
especially after the first few doses, or if the dose is increased. If any of these
occur, do not drive, operate machinery or do anything else that could be dangerous.
Be careful when drinking alcohol while you are taking this medicine.
If you drink alcohol, symptoms such as dizziness, lightheadedness or fainting may
If you feel light-headed, dizzy or faint when getting out of bed or standing up, get
Dizziness, lightheadedness or fainting may occur when you begin to take Hydopa, or
if the dose is increased. This happens especially when you get up quickly from a sitting
or lying position.
Standing up slowly, especially when you get up from bed or chairs, will help your
body get used to the change in position and blood pressure. This problem usually goes
away after the first few days.
If this problem continues or gets worse, talk to your doctor.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you
are taking Hydopa.
This medicine helps most people with high blood pressure, but it may have unwanted
side effects in a few people. All medicines can have side effects. Sometimes they
are serious, most of the time they are not. You may need medical attention if you
get some of the side effects.
Do not be alarmed by the following lists of side effects. You may not experience any
Ask your doctor or pharmacist to answer any questions you may have.
Tell your doctor or pharmacist if you notice any of the following and they worry you:
The above list includes the more common side effects of your medicine. They are usually
mild and short-lived. These side effects may occur at the beginning of treatment or
when the dose is increased.
If any of the following happen, tell your doctor immediately or go to Accident and
Emergency at your nearest hospital:
fever shortly after starting Hydopa, for example, within the first 3 months
yellowing of the eyes or skin (jaundice)
darker urine than normal due to liver problems
swelling of the feet or lower legs
nightmares, feeling strange or depressed
signs of frequent or worrying infections such as fever, chills, sore throat or mouth
bleeding or bruising more easily than normal
signs of anaemia such as tiredness, looking pale together with being short of breath
when exercising and tingling or numbness of the hands or feet
itchy skin rash or other skin problems
a slow heart beat or pulse
worsening of angina (chest pain).
larger breasts than normal, especially in men.
The above list includes serious side effects. You may need urgent medical attention.
These side effects are rare.
Tell your doctor or pharmacist if you notice anything that is making you feel unwell.
Other side effects not listed above may also occur in some people.
Do not be alarmed by this list of possible side effects. You may not experience any
After using Hydopa
Keep your tablets in the bottle until it is time to take them.
If you take the tablets out of the bottle they may not keep well.
Keep your tablets in a cool dry place where the temperature stays below 25°C.
Do not store Hydopa or any other medicine in the bathroom or near a sink. Do not leave
it on a window sill or in the car.
Heat and dampness can destroy some medicines.
Keep it where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place
to store medicines.
If your doctor tells you to stop taking this medicine or the expiry date has passed,
ask your pharmacist what to do with any medicine that is left over.
What it looks like
Hydopa tablets are round and yellow, marked "MD" over "250" on one side and "G" on
Each pack contains 100 tablets.
The active ingredient in Hydopa is methyldopa (as sesquihydrate). Each Hydopa tablet
contains methyldopa (as sesquihydrate) equivalent to 250 mg of anhydrous methyldopa.
The tablets also contain the following inactive ingredients:
anhydrous citric acid
sodium starch glycollate
colloidal anhydrous silica
Opadry Yellow OY-8462 (includes colours 104, 110, 171).
Hydopa tablets contain galactose.
Hydopa is supplied in Australia by:
Alphapharm Pty Ltd (A Viatris Company)
Level 1, 30 The Bond
30-34 Hickson Road
Millers Point NSW 2000
This leaflet was prepared on
8 September 2021.
AUST R 69482