Neupro

Do not use if you have ever had an allergic reaction to Neupro® or any of the ingredients listed at the end of the CMI. Do not use if you need to have an MRI or cardioversion. Talk to your doctor if you have any other medical conditions, take any other medicines, or are pregnant or plan to become pregnant or are breastfeeding. For more information, see Section 2. What should I know before I use Neupro®? in the full CMI.

Some medicines may interfere with Neupro® and affect how it works. A list of these medicines is in Section 3. What if I am taking other medicines? in the full CMI.

A Neupro® patch is applied to the skin once a day for 24 hours and is then replaced around the same time every day. The dose varies from patient to patient. More instructions can be found in Section 4. How do I use Neupro®? in the full CMI.

For more information, see Section 5. What should I know while using Neupro®? in the full CMI.

Common side effects: dizziness, lightheadedness, vertigo, abnormal movements e.g. muscle twitching or spasms, sleep issues, unusual dreams, nightmares, application site reactions (itching or redness), sweating, feeling tired or weak, hiccups, nausea, vomiting, constipation, indigestion, dry mouth, headache, swelling of legs or feet, feeling weak and tired or weight loss.
Serious potential side effects: hallucinations, compulsive behaviour, psychotic disorders including abnormal thinking about reality and behaviour, confusion, disorientation, allergic reaction (shortness of breath, wheezing or difficulty breathing, swelling of the face and lips, tongue or other body parts, rash, itching or hives on the skin), irregular heartbeat, increased heart rate (palpitations), involuntary muscle spasms (seizure, convulsion), loss of consciousness, visual disturbances such as seeing colours or lights or blurred vision, falling, fainting.
For more information, including what to do if you have any side effects, see Section 6. Are there any side effects? in the full CMI.

Active ingredient(s): rotigotine (pronounced "roe-TIG-oh-teen")

This leaflet provides important information about using Neupro®. You should also speak to your doctor or pharmacist if you would like further information or if you have any concerns or questions about using Neupro®.

Where to find information in this leaflet:

Neupro® contains the active ingredient rotigotine. Neupro® belongs to a group of medicines called non-ergot dopamine agonists which stimulate dopamine receptors in the brain to increase the effects of dopamine.

Neupro® is used in the treatment of Parkinson’s disease and Restless Legs Syndrome (RLS).

Parkinson’s disease

This is a disease of the nervous system that mainly affects body movement. The main symptoms are shaking (tremor), muscle stiffness and slow unsteady movement. If untreated, Parkinson’s disease can cause difficulty in performing daily activities.

Parkinson’s disease is caused by the brain not making enough of a chemical called dopamine.

Dopamine helps the brain to control muscle movement. When too little dopamine is produced slowness of movement results.

Restless Legs Syndrome (RLS)

RLS is a condition characterised by unpleasant sensations in the legs and the irresistible urge to move in an effort to relieve these feelings. There is a sense of uneasiness, restlessness, and itching often accompanied by twitching and pain in the legs when sitting or lying down, especially in bed at night. Occasionally the arms may also be affected. RLS is thought to be due to insufficient dopamine levels in the brain.

If any of the above applies to you (or you are not sure), talk to your doctor or pharmacist before using Neupro®.

Have any other medical conditions, including:

During treatment, you may be at risk of developing certain side effects. It is important you understand these risks and how to monitor for them. See additional information under Section 6. Are there any side effects?

Check with your doctor if you are pregnant or intend to become pregnant.

The effects of Neupro® on pregnancy and the unborn child are not known. Neupro® should not be used during pregnancy.

Talk to your doctor if you are breastfeeding or intend to breastfeed.

Neupro® is not recommended if you are breastfeeding, as it is likely to reduce the amount of milk you produce. Neupro® may also pass into your breast milk and affect your baby. If your doctor says you need to use Neupro®, you should stop breastfeeding.

Do not give this medicine to a child or adolescent. The safety and effectiveness in children and adolescents has not been established.

Tell your doctor or pharmacist if you are taking any other medicines, including any medicines, vitamins or supplements that you buy without a prescription from your pharmacy, supermarket or health food shop.

Some medicines may interfere with Neupro® and affect how it works.

Check with your doctor or pharmacist if you are not sure about what medicines, vitamins or supplements you are taking and if these affect Neupro®.

Follow all directions given to you by your doctor carefully. They may differ from the information contained in this leaflet.

The dose varies from patient to patient. Your doctor may start you on a low dose of Neupro® first and slowly increase the amount of medicine until you are taking enough to control your condition.

Continue taking Neupro for as long as your doctor tells you. This medicine helps to control your condition but does not cure it. It is important to keep using your medicine even if you feel well.

You should stick a Neupro® patch onto the skin once a day. You should leave the patch on your skin for 24 hours and then replace it with a new one. Make sure that you take the old patch off before sticking on the new one. You should replace the patch at around the same time every day.

Put the sticky side of the patch onto clean, dry, healthy skin on one of the following areas at a time:

To help avoid skin irritation, stick the patch onto a different area of skin each day (for example, on the right side of your body one day, then on the left side the next day and on your upper body one day, then on your lower body). You should not stick Neupro® on the same area of skin twice within 14 days.

Things to remember

Each patch is packed in a sachet containing the medicine. You should stick Neupro® onto your skin as soon as you have opened the sachet and removed the protective liner.

It is important to ensure you press the patch firmly for 20 – 30 seconds.

Wash your hands with soap and water immediately after handling the patch.

Before you put on a new patch, slowly and carefully peel off the used patch.

Gently washing the area with warm water and mild soap should remove any adhesive that stays on your skin after you remove the patch.

You can also use a small amount of baby oil to remove any adhesive that won’t wash off.

Do not use alcohol or other dissolving liquids such as nail polish remover or other solvents as these may irritate your skin.

If the patch falls off, a new patch should be applied for the rest of the day, then replace the patch at the same time as usual.

Neupro® should be used regularly at the same time each day. If you miss your dose at the usual time, remove the old patch and use a new patch as soon as you remember.

If you have forgotten to stick on a new patch after removing the old one, use a new patch as soon as you remember. On the following day you should use a new patch at the usual time.

Do not take a double dose to make up for the dose you missed.

If you think that you have used too much Neupro® (for example you have used more patches than your doctor told you to), you may need urgent medical attention.

You should immediately:

Using higher dosages of Neupro® than your doctor has prescribed may cause nausea, vomiting, low blood pressure, fast heart beats, hallucinations, confusion or extreme sleepiness.

You should do this even if there are no signs of discomfort or poisoning.

Remind any doctor, dentist or pharmacist you visit that you are using Neupro®.

Be careful before you drive or use any machines or tools until you know how Neupro® affects you.

Neupro® may make you feel very drowsy and may cause some people to fall asleep suddenly without any apparent warning of sleepiness.

If you feel very drowsy, or experience episodes of falling asleep suddenly without feeling sleepy, do not drive or operate machinery or perform any other dangerous activities, and contact your doctor.

Tell your doctor if you drink alcohol.

Combining Neupro® and alcohol can make you more drowsy. Your doctor may suggest you avoid alcohol while you are being treated with Neupro®.

Follow the instructions in the carton on how to take care of your medicine properly.

Store it in a cool dry place away from moisture, heat or sunlight; for example, do not store it:

Keep it where young children cannot reach it.

Used patches still contain active ingredient, which may be harmful to others. Fold the used patch with the sticky side inwards. Put the patch in the original sachet and then throw it away safely, out of the reach of children.

Do not flush them down the toilet, nor place them in liquid waste disposal systems.

If you no longer need to use this medicine or it is out of date, take it to any pharmacy for safe disposal.

Do not use this medicine after the expiry date.

All medicines can have side effects. If you do experience any side effects, most of them are minor and temporary. However, some side effects may need medical attention.

See the information below and, if you need to, ask your doctor or pharmacist if you have any further questions about side effects.

Tell your doctor or pharmacist if you notice anything else that may be making you feel unwell.

Other side effects not listed here may occur in some people.

After you have received medical advice for any side effects you experience, you can report side effects to the Therapeutic Goods Administration online at www.tga.gov.au/reporting-problems . By reporting side effects, you can help provide more information on the safety of this medicine.

Always make sure you speak to your doctor or pharmacist before you decide to stop taking any of your medicines.

This medicine is only available with a doctor's prescription.

Do not take this medicine if you are allergic to any of these ingredients.

Neupro® is a transdermal patch that is available in four different strengths:

Neupro® 2 mg/24 h AUST R 131370

Neupro® 4 mg/24 h AUST R 131381

Neupro® 6 mg/24 h AUST R 131382

Neupro® 8 mg/24 h AUST R 131383

1 mg/24 h and 3 mg/24 h transdermal patches are not available in Australia.

The patches are thin and have three layers. They are square shaped with rounded edges. The outside is tan-coloured and is imprinted with either Neupro® 2 mg/24 h, Neupro® 4 mg/24 h, Neupro® 6 mg/24 h or Neupro® 8 mg/24 h.

Neupro® is available in cartons containing 28 patches, which are individually sealed in sachets.

UCB Pharma

A division of UCB Australia Pty Ltd

Phone: +61 3 9828 1800

Website: www.ucbpharma.com.au 

E-mail: [email protected] 

This leaflet was prepared in October 2025.