Rasagiline mesilate (ra-SA-ji-leen MES-i-late)
Consumer Medicine Information
What is in this leaflet
This leaflet answers some common questions about Rasagiline-Teva. It does not contain
all the available information. It does not take the place of talking to your doctor
All medicines have risks and benefits. Your doctor has weighed the risks of you taking
Rasagiline-Teva against the benefits they expect it will have for you.
If you have any concerns about taking this medicine, ask your doctor or pharmacist.
Keep this leaflet with the medicine.
You may need to read it again.
What Rasagiline-Teva is used for
Rasagiline-Teva is used to treat the symptoms of Parkinson's disease. It can be taken
with or without dopamine agonist or levodopa therapy.
Parkinson's disease is a condition of the brain that mainly affects body movement.
The three main symptoms of Parkinson's disease are:
Slow and unsteady movement
In Parkinson's disease, there is a loss of cells producing dopamine in certain areas
in the brain.
Rasagiline-Teva works by increasing and maintaining the level of dopamine in your
brain which will decrease symptoms of Parkinson's disease.
Ask your doctor if you have any questions about why this medicine has been prescribed
Your doctor may have prescribed it for another reason.
This medicine is available only with a doctor's prescription. It is not addictive.
Rasagiline-Teva should not be given to children under 18 years of age as there is
no specific information about such use. Always ask your doctor before giving medicines
Before you take Rasagiline-Teva
When you must not take it.
Do not take Rasagiline-Teva if you have ever had an allergic reaction to rasagiline
or any of the ingredients listed at the end of this leaflet.
If you have an allergic reaction you may get a skin rash, have difficulty in breathing,
get symptoms of hay fever or feel faint.
If you are already taking Rasagiline-Teva, do not take another medicine called:
monoamine oxidase inhibitors (MAOI), whether used to treat depression, Parkinson's
disease or any other condition
Other medicinal and natural products without prescription which have MAOI activity
(e.g. St. John's Wort)
pethidine, a strong pain killer
ciprofloxacin, an antibiotic used to treat infection
Wait, at least 14 days between stopping Rasagiline-Teva and starting your MAOI medicine
Do not take Rasagiline-Teva if you have a problem with your liver.
Do not take Rasagiline-Teva after the expiry date (EXP) printed on the pack. It may
not work as well
Do not take Rasagiline-Teva if the packaging is torn or shows signs of having been
If you are not sure whether you should start taking this medicine, talk to your doctor.
Before you start to take it
Tell your doctor if you have allergies to any other medicines, foods, preservatives
Tell your doctor if you have a problem with your liver.
Tell your doctor if you are pregnant or plan to become pregnant or are breast-feeding.
Your doctor can discuss with you the risks and benefits involved.
Tell your doctor if you smoke.
Nicotine can affect the amount of rasagiline that is in your body.
Tell your doctor if you notice any unusual skin lumps or moles which are new or have
Taking other medicines
Tell your doctor or pharmacist if you are taking any other medicines, including any
that you buy without a prescription from a pharmacy, supermarket or health food shop.
The following medicines require specific medical advice before being taken together
medicines used to treat depression, anxiety, panic disorder, obsessive compulsive
disorder or pre-menstrual dysphoric disorders. Examples of such medicines include
selective serotonin reuptake inhibitors (SSRIs), tricyclic and tetracyclic antidepressants
other medicines used to treat depression called fluoxetine and fluvoxamine
Wait at least 5 weeks between stopping fluoxetine treatment and starting treatment
with Rasagiline-Teva, and 14 days between stopping Rasagiline-Teva treatment and starting
treatment with fluoxetine or fluvoxamine.
dextromethorphan, a medicine for cough
substances with sympathomimetic activity such as those present in 'cold and flu' oral
tablets and nasal drops containing ephedrine or pseudoephedrine
clozapine, a medicine used to treat schizophrenia
other medicines used to treat symptoms of Parkinson's disease
Your doctor or pharmacist can tell you what to do if you are taking this or any other
If you have not told your doctor about any of these things, tell them before you take
How to take rasagiline-teva
Follow all directions given to you by your doctor or pharmacist carefully.
They may differ from the information contained in this leaflet.
If you do not understand the instructions on the label, ask your doctor or pharmacist
How much to take
Your doctor will tell you how much Rasagiline-Teva to take each day. Take the amount
your doctor tells you to.
The usual dose for Rasagiline-Teva is one tablet of 1 mg taken orally once a day.
How to take it
Swallow the tablets whole with a full glass of water.
Rasagiline-Teva can be taken with or without food.
When to take it
Take your medicine at about the same time each day.
Taking it at the same time each day will have the best effect. It will also help you
remember when to take it.
How long to take it
Do not stop taking this medicine without first checking with your doctor.
If you forget to take it
If it is almost time for your next dose, skip the dose you missed and take your next
dose when you are meant to. Otherwise, take it as soon as you remember, and then
go back to taking your medicine as you would normally.
Do not take a double dose to make up for the dose that you missed.
This may increase the chance of you getting an unwanted side effect.
If you are not sure what to do, ask your doctor or pharmacist.
If you have trouble remembering to take your medicine, ask your pharmacist for some
If you take too much (Overdose)
Immediately telephone your doctor or Poisons Information Centre (Telephone 13 11 26)
for advice, or go to the Accident and Emergency department at your nearest hospital
if you think that you or anyone else may have taken too much Rasagiline-Teva. Do this
even if there are no signs of discomfort or poisoning. Keep telephone numbers for
these places handy.
While you are taking Rasagiline-Teva
Things you must do
Tell your doctor immediately if you become pregnant while taking Rasagiline-Teva.
Tell all doctors, dentists and pharmacists who are treating you that you are taking
Rasagiline-Teva, especially if you are being started on any new medicines.
Keep all of your doctor's appointments so that your progress can be checked.
Things you must not do
Do not take Rasagiline-Teva to treat any other complaints unless your doctor tells
Do not give your medicine to anyone else, even if their symptoms seem similar to yours.
Do not drive, operate machinery or work at heights during treatment if you have fallen
asleep without warning, prior to the use of Rasagiline-Teva.
Things to be aware of
As with any new medicine, make sure you know how Rasagiline-Teva affects you before
you drive or operate machinery.
Rasagiline-Teva may cause you to feel sleepy in the daytime during daily activities.
Be careful when drinking alcohol while you are taking this medicine.
If you feel light-headed, dizzy or faint when getting out of bed or standing up, get
up slowly. Standing up slowly, especially when you get up from a bed or chair, will
help your body get used to the change in position and blood pressure. If this problem
continues or gets worse, talk to your doctor.
Scientific evidence suggests that Parkinson's disease is associated with a higher
risk of skin cancer, (including melanoma). During the development (placebo-controlled
clinical trials), melanoma was observed in both Rasagiline-Teva - and placebo-treated
patients (around 0.5% vs 0.2% respectively). People with Parkinson's disease, including
those taking Rasagiline-Teva, should undergo periodic examination of the skin.
Eating excessive amounts of foods rich in tyramine (e.g. aged cheese, red wine) while
you are taking Rasagiline-Teva could very rarely cause an increase in your blood pressure
and should be avoided. If you do eat these foods while you are taking Rasagiline-Teva
and do not feel well, you should contact your treating doctor. Your treating doctor
or pharmacist can advise you on what foods are rich in tyramine and what your risk
of having a reaction may be.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you
are taking Rasagiline-Teva.
This medicine helps most people with Parkinson's disease, but it may have unwanted
side effects in some people. All medicines can have side effects. Sometimes they are
serious most of the time they are not. You may need medical treatment if you get some
of the side effects.
Do not be alarmed by the following lists of side effects. You may not experience any
Ask your doctor or pharmacist to answer any questions you may have.
Tell your doctor if you notice any of the following side effects and they worry you:
accidental injury (primarily falls)
dizziness when you stand up due to low blood pressure
difficulty in moving normally
obsessive thoughts or impulsive behaviour.
Tell your doctor or pharmacist if you notice anything else that is making you feel
Some people may get other side effects while using Rasagiline-Teva.
After taking Rasagiline-Teva
Keep Rasagiline-Teva in the blister pack until it is time to take them.
Keep Rasagiline-Teva in a cool dry place where the temperature stays below 25°C.
Do not store Rasagiline-Teva or any other medicine in the bathroom or near a sink
or stove. Do not leave it on a window sill or in the car. Heat and dampness can destroy
Keep Rasagiline-Teva where young children cannot reach it.A locked cupboard at least
one-and-a-half metres above ground is a good place to store medicines.
Dispose of the tablets where children cannot reach them.
Ask your pharmacist what to do with any Rasagiline-Teva you may have left over if
your doctor tells you to stop using it, or you find that the tablets have passed the
What Rasagiline-Teva tablets look like
White to off-white, round, flat, bevelled tablets, debossed with ''GIL'' and ''1''
underneath on one side.
Rasagiline-Teva tablets contain 1 mg of rasagiline (as rasagiline mesilate).
The tablets also contain:
silica – colloidal anhydrous
* vegetable origin
Rasagiline-Teva is supplied by:
Teva Pharma Australia Pty Ltd
37 Epping Rd
Macquarie Park, NSW, 2113
Telephone: 1800 288 382
This leaflet was prepared in March 2018
Australian Registration Number:
AUST R 294880