Consumer Medicine Information
What is in this leaflet
This leaflet answers some common questions about XALAPROST. It does not contain all
the available information. It does not take the place of talking to your doctor or
All medicines have risks and benefits. Your doctor has weighed the risks of you taking
XALAPROST against the benefits they expect it will have for you.
If you have any concerns about taking this medicine, ask your doctor or pharmacist.
Keep this leaflet with the medicine.
You may need to read it again.
What XALAPROST is used for
XALAPROST is used to lower raised pressure in the eye and to treat glaucoma. Glaucoma
is a condition in which the pressure of fluid in the eye may be high. However, some
people with glaucoma may have normal eye pressure.
Glaucoma is usually caused by a build up of the fluid which flows through the eye.
This build up occurs because the fluid drains out of your eye more slowly than it
is being pumped in. Since new fluid continues to enter the eye, joining the fluid
already there, the pressure continues to rise. This raised pressure may damage the
back of the eye resulting in gradual loss of sight. Damage can progress so slowly
that the person is not aware of this gradual loss of
sight. Sometimes even normal eye pressure is associated with damage to the back of
There are usually no symptoms of glaucoma. If glaucoma is not treated it can lead
to serious problems, including total blindness. In fact, untreated glaucoma is one
of the most common causes of blindness.
XALAPROST belongs to a family of medicines called prostaglandin agonists.
It lowers the pressure in the eye by allowing more fluid to flow out from within your
Although XALAPROST helps control your glaucoma it does not cure it. So you must keep
using it until your doctor tells you to stop.
XALAPROST is used, either alone or in combination with other eye medicines, to lower
raised pressure within your eye.
Ask your doctor if you have any questions about why XALAPROST has been prescribed
Your doctor may have prescribed it for another reason.
XALAPROST is not addictive.
XALAPROST is not recommended for use in children. The safety and effectiveness of
XALAPROST in children have not been established.
Before you use XALAPROST
When you must not use it
Do not use XALAPROST if you have an allergy to:
any medicine containing latanoprost
any of the ingredients listed at the end of this leaflet
any other similar medicines
Some of the symptoms of an allergic reaction may include:
asthma, wheezing or shortness of breath
swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing
hives, itching or skin rash
Do not use this medicine if you are pregnant.
It may affect your developing baby if you take it during pregnancy.
Do not use this medicine after the expiry date printed on the pack or if the packaging
is torn or shows signs of tampering.
If it has expired or is damaged, return it to your pharmacist for disposal.
If you are not sure whether you should start using this medicine, talk to your doctor.
Before you start to use it
Tell your doctor if you have allergies to any other medicines, foods, preservatives
Tell your doctor if you have or have had any of the following medical conditions:
any other types of glaucoma
any other eye conditions.
Tell your doctor if you are pregnant or breast-feeding or plan to become pregnant
Your doctor can discuss with you the risks and benefits involved.
If you have not told your doctor about any of the above, tell them before you start
Taking other medicines
Tell your doctor or pharmacist if you are taking any other medicines, including any
that you get without a prescription from your pharmacy, supermarket or health food
Some medicines and XALAPROST may interfere with each other. These include:
eye drops which contain an ingredient called thiomersal. If using such eye drops as
well as XALAPROST, you should wait at least 5 minutes between using these eye drops
some other eye drops that contain a prostaglandin. The use of two or more prostaglandin
eye drops at the same time is not recommended.
These medicines may be affected by XALAPROST or may affect how well it works. You
may need different amounts of your medicines, or you may need to use different medicines.
Your doctor and pharmacist have more information on medicines to be careful with or
avoid while taking this medicine.
How to use XALAPROST
Follow all directions given to you by your doctor or pharmacist carefully.
They may differ from the information contained in this leaflet.
If you do not understand the instructions on the box, ask your doctor or pharmacist
If you are being changed from one eye drop to another, follow your doctor's instructions
carefully as to when to stop the old drops and when to start the new drops.
How much to use
The usual dose of XALAPROST is one drop into the affected eye, or eyes, once daily.
How to use it
If you are wearing soft contact lenses, remove them before putting the drops in your
The preservative in XALAPROST (benzalkonium chloride) may be deposited in soft contact
lenses. You can put your soft contact lenses back into your eyes 15 minutes after
you have used XALAPROST.
If using other eye drops in addition to XALAPROST, wait at least 5 minutes before
putting any other drops in your eye(s).
Be careful not to touch the dropper tip against your eye, eyelid or anything else.
Touching the dropper tip against something may contaminate the eye drops and give
you an eye infection.
You may find it easier to put drops in your eye while you are sitting or lying down.
1. Wash your hands well with soap and water.
2. Twist off the protective overcap from the bottle.
3. Unscrew the inner cap.
4. Use your finger to gently pull down the lower eyelid of your affected eye.
5. Tilt your head back and look up.
6. Place the tip of the bottle close to but not touching your eye. Squeeze the bottle
gently so that only one drop goes into your eye, then release the lower eyelid. Close
your eye. Do not blink or rub your eye.
7. While your eye is closed, place your index finger against the inside corner of your
eye and press against your nose for about two minutes. This will help to stop the
medicine from draining through the tear duct to the nose and throat, from where it
can be absorbed into other parts of your body. Ask your doctor for more specific instructions
on this technique.
8. Screw the inner cap back on the bottle.
9. Wash your hands again with soap and water to remove any residue.
You may feel a slight burning sensation in the eye shortly after using the eye drops.
If this persists, or is very uncomfortable, contact your doctor or pharmacist.
When to use it
Use XALAPROST at about the same time each day, preferably in the evening, unless your
doctor tells you otherwise.
Using it at the same time each day will have the best effect on your eye pressure.
It will also help you remember when to use it.
How long to use it
Continue using XALAPROST every day for as long as your doctor tells you.
XALAPROST helps to control your condition, but does not cure it.
If you forget to use it
If you miss a dose, skip the dose you missed and administer your next dose when you
are meant to.
Otherwise, use it as soon as you remember, and then go back to using your medicine
as you would normally.
Do not administer a double dose to make up for the dose that you missed.
If you are not sure what to do, ask your doctor or pharmacist.
If you have trouble remembering to use your medicine, ask your pharmacist for some
If you use too much (overdose)
If you accidentally put several drops in your eye, immediately rinse your eye with
Immediately telephone your doctor or the Poisons Information Centre (telephone 13
11 26) for advice, or go to Accident and Emergency at the nearest hospital, if you
think that you or anyone else may have swallowed XALAPROST. Do this even if there
are no signs of discomfort or poisoning.
You may need urgent medical attention.
While you are using XALAPROST
Things you must do
To make sure XALAPROST is working properly, have your eye pressure checked regularly.
Have your eyes checked regularly for any other changes, including a change in eye
A slow change in eye colour, which may be permanent, has been reported to occur in
some patients who use XALAPROST. Your doctor will decide whether you should continue
If you develop an eye infection, receive an eye injury, or have eye surgery tell your
Your doctor may tell you to use a new container of XALAPROST because of possible contamination
of the old one, or may advise you to stop your treatment with XALAPROST.
If you are about to be started on any new medicine, remind your doctor and pharmacist
that you are taking XALAPROST.
Tell any other doctors, dentists and pharmacists who treat you that you are using
If you become pregnant while using this medicine, tell your doctor immediately.
Keep all of your doctor's appointments so that your progress can be checked.
Things you must not do
Do not use XALAPROST to treat any other complaints unless your doctor tells you to.
Do not give XALAPROST to anyone else, even if they have the same condition as you.
Do not stop using your medicine or lower the dosage without checking with your doctor.
If you stop using your eye drops, your eye pressure may rise again and damage to your
eye may occur.
Things to be careful of
Be careful driving or operating machinery until you know how XALAPROST affects you.
XALAPROST generally does not cause any problems with your ability to drive a car or
operate machinery. However, it may cause blurred vision in some people. Make sure
you know how you react to XALAPROST or that your vision is clear before driving a
car or operating machinery.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you
are using XALAPROST.
This medicine helps most people with glaucoma, but it may have unwanted side effects
in a few people. All medicines can have side effects. Sometimes they are serious,
most of the time they are not. You may need medical attention if you get some of the
Do not be alarmed by the following lists of side effects. You may not experience any
Ask your doctor or pharmacist to answer any questions you may have.
Tell your doctor or pharmacist if you notice any of the following and they worry you:
a slow change in eye colour over a period of time. The iris may become browner in
colour and appear darker. This change may be permanent and more noticeable if you
are only being treated in one eye
blurred vision, double vision or other visual problems
irritation or feeling of having something in the eye. This may be worse during the
first two or three days of using XALAPROST
redness, burning or watering of the eye(s)
discharge, itching of the eye(s), crusty eyelashes
darkening, thickening, lengthening or an increase in the number of eye lashes and
the fine hair on the eyelids
misdirected eyelashes sometimes causing eye irritation
darkening of the skin of the eyelids
crusting, redness, thickening, itching or burning of the eyelids
sensitivity to light
painful, urgent or frequent urination.
If any of the following happen, tell your doctor immediately or go to Accident and
Emergency at your nearest hospital:
wheezing, difficulty in breathing (asthma or worsening of asthma)
shortness of breath
you notice strong, rapid or irregular heartbeats
swelling of the face, lips, mouth, tongue or throat which may cause difficulty in
swallowing or breathing
white deposits or plaque in the cornea causing the transparent front part of your
eye to look white or cloudy.
The above list includes very serious side effects. You may need urgent medical attention
or hospitalisation. These side effects are very rare.
Tell your doctor or pharmacist if you notice anything that is making you feel unwell.
Other side effects not listed above may also occur in some people.
After using XALAPROST
Before opening XALAPROST, keep the bottle in its box in a refrigerator (2°C to 8°C)
protected from light.
After opening XALAPROST, keep the bottle in its box in a cool place where the temperature
stays below 25°C (but do not freeze). Keep the box properly closed and protected from
Put the top back on the bottle as soon as you are finished using the drops, to avoid
contamination of the eye drops.
Do not store XALAPROST or any other medicine in the bathroom or near a sink. Do not
leave it on a window sill or in the car. Do not carry the eye drops in pockets of
Heat and dampness can destroy some medicines.
Keep it where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place
to store medicines.
Write the date on the bottle when you open the eye drops, and dispose of any remaining
solution after four weeks.
Open a new bottle every four weeks.
Eye drops contain a preservative which helps prevent germs growing in the solution
for the first four weeks after opening the bottle. After this time there is a greater
risk that the drops may become contaminated and cause an eye infection.
If your doctor tells you to stop taking this medicine or the expiry date has passed,
ask your pharmacist what to do with any medicine that is left over.
What it looks like
XALAPROST eye drops come in a plastic bottle with a dropper and screw cap inside a
protective overcap. The drops are a clear, colourless solution.
When you first receive your XALAPROST bottle, it will appear half full. This corresponds
to 2.5 mL of eye drop solution, giving a minimum of 80 drops. This volume is enough
to last 4 weeks if used in both eyes.
XALAPROST contains 50 micrograms per mL of latanoprost as the active ingredient. Each
drop contains approximately 1.5 micrograms of latanoprost.
The eye drops also contain the following inactive ingredients:
dibasic sodium phosphate
monobasic sodium phosphate monohydrate
water for injections.
Viatris Pty Ltd
Level 1, 30 The Bond
30-34 Hickson Road
Millers Point NSW 2000
Phone: 1800 274 276
This leaflet was prepared in March 2023.
Australian registration number:
AUST R 217151