Metronidazole 0.75% w/w
Consumer Medicine Information
What is in this leaflet
This leaflet answers some common questions about Zidoval Vaginal Gel. It does not
contain all the available information. It does not take the place of talking to your
doctor or pharmacist.
All medicines have risks and benefits. Your doctor has weighed the risks of you taking
Zidoval against the benefits they expect it will have for you.
If you have any concerns about taking this medicine, ask your doctor or pharmacist.
Keep this leaflet with the medicine.
You may need to read it again.
What Zidoval is used for
Zidoval Vaginal Gel contains an active ingredient, metronidazole. Metronidazole is
an antibacterial agent.
Zidoval is used to treat infection of the vagina (bacterial vaginosis) caused by certain
bacteria. It is not suitable for all types of vaginal infections. By applying Zidoval
directly into the vagina, metronidazole can kill the bacteria at the site of the infection.
Ask your doctor if you have any questions about why this medicine has been prescribed
Your doctor may have prescribed it for another reason.
This medicine is available only with a doctor's prescription.
Before you use Zidoval
When you must not use it
Do not use Zidoval if you have an allergy to:
any medicine containing metronidazole
any of the ingredients listed at the end of this leaflet.
Some of the symptoms of an allergic reaction may include:
shortness of breath
wheezing or difficulty breathing
swelling of the face, lips, tongue or other parts of the body
rash, itching or hives on the skin.
Do not give Zidoval to a child under the age of 12 years.
Safety and effectiveness in children younger than 12 years have not been established.
Do not use this medicine after the expiry date printed on the pack or if the packaging
is torn or shows signs of tampering.
If it has expired or is damaged, return it to your pharmacist for disposal.
If you are not sure whether you should start using this medicine, talk to your doctor.
Before you start to use it
Tell your doctor if you have allergies to any other medicines, foods, preservatives
Tell your doctor if you have or have had any of the following medical conditions:
a disease of the blood, liver, kidneys or central nervous system
Cockayne syndrome, also called Neill-Dingwall syndrome.
Tell your doctor if you are pregnant or breast-feeding.
Your doctor can discuss with you the risks and benefits of using Zidoval whilst pregnant
Tell your doctor if you have, or think you may have vaginal thrush (candidiasis).
The symptoms of vaginal thrush may become more noticeable when you use Zidoval gel
and you may need another treatment from your doctor for this.
Tell your doctor if:
you are having your period or are about to start your period
you have taken disulfiram (Antabuse) in the past 2 weeks.
Disulfiram is used to help people who have a drinking problem. If Zidoval and disulfiram
are taken close together, serious unwanted effects may occur.
If you have not told your doctor about any of the above, tell them before you start
Taking other medicines
Tell your doctor or pharmacist if you are taking any other medicines, including any
that you get without a prescription from your pharmacy, supermarket or health food
Some medicines and Zidoval may interfere with each other. These include:
medicine to prevent blood clotting (e.g. warfarin)
carmustine (BCNU) or cyclophosphamide.
These medicines may be affected by Zidoval or may affect how well it works. You may
need different amounts of your medicines, or you may need to take different medicines.
Your doctor and pharmacist have more information on medicines to be careful with or
avoid while using this medicine.
Discuss with your doctor whether you may drink alcohol during treatment with Zidoval.
Drinking alcohol when using Zidoval may make you feel dizzy or sick.
How to use Zidoval
Follow all directions given to you by your doctor or pharmacist carefully.
They may differ from the information contained in this leaflet.
If you do not understand the instructions in this leaflet, ask your doctor or pharmacist
How much to use
Each dose consists of one applicator filled with 5 g of Zidoval gel.
How to use it
Your box of Zidoval contains a tube of vaginal gel and five single use vaginal applicators.
To ensure maximum hygiene, always:
Wash your hands before opening the tube or touching the applicator
Use a new applicator for each dose
Dispose of the used applicator in the rubbish bin.
Opening the tube
Before using Zidoval Vaginal Gel for the first time, puncture the metal seal on the
tube. To do this, unscrew the cap from the tube and pierce the seal using the pointed
tip of the cap.
Filling the applicator
Remove an applicator from its wrapper. Unscrew the cap from the tube and screw the
open end of the applicator onto the tube.
Squeeze the tube slowly from the bottom to fill the applicator with gel. The plunger
will move as the applicator fills and will stop moving when the applicator contains
the correct amount of gel.
Unscrew the applicator and replace the cap on the tube.
Inserting the applicator
Hold the filled applicator by its barrel and gently insert it into your vagina as
far as it will comfortably go.
You may find it easiest to do this whilst lying on your back with your knees bent.
Otherwise choose any position you find comfortable.
Applying the gel
Slowly press the plunger to deposit the gel into your vagina. Continue pressing until
the plunger stops. This will ensure you have released the correct amount of gel.
Remove the applicator from the vagina and put it in the rubbish bin.
When to use it
Use Zidoval at bedtime.
Vaginal medicines can leak out of the vagina during treatment. Using Zidoval at bedtime
will help reduce leakage. Using Zidoval at the same time each day will also help you
remember when to use it.
Wear a panty liner or sanitary napkin during treatment to help keep the medicine from
getting on your clothing. Do not use tampons as they may soak up the medicine and
stop you getting the full dose.
How long to use it
Apply Zidoval for 5 days in a row or for as long as your doctor tells you.
To help prevent reinfection, always complete the full course of treatment even if
your symptoms start to clear up within a few days.
If you forget to use it
If you forget to have a dose of Zidoval gel, use it as soon as you remember and continue
with your treatment as before.
If, by the time you remember, it is time to have your next dose, do not double-up
on your treatment. Have your original missed dose and continue your treatment as usual.
Never have more than one dose of the gel a day to make up for missed doses.
If you are not sure what to do, ask your doctor or pharmacist.
If you have trouble remembering to use your medicine, ask your pharmacist for some
If you use too much (overdose)
Telephone your doctor or the Poisons Information Centre (telephone 13 11 26) for advice,
or go to Accident and Emergency at the nearest hospital, if you think that you or
anyone else may have accidentally swallowed Zidoval Vaginal Gel or may have used too
much of it. Do this even if there are no signs of discomfort or poisoning.
You may need medical attention.
While you are using Zidoval
Things you must do
If you are about to be started on any new medicine remind your doctor and pharmacist
that you are using Zidoval.
Tell any other doctors and pharmacists who treat you that you are using this medicine.
If you are going to have surgery, tell the surgeon or anaesthetist that you are using
It may affect other medicines used during surgery.
As with all vaginal infections avoid sexual intercourse during the infection and whilst
you are using Zidoval gel.
If you become pregnant while using this medicine, tell your doctor immediately.
If you are about to have any blood tests tell your doctor that you are using this
It may interfere with the results of some tests.
Keep all of your doctor's appointments so that your progress can be checked.
It is important that your doctor check your progress after you finish using Zidoval.
This is to make sure that the infection has cleared up.
Things you must not do
Do not use Zidoval to treat any other complaints unless your doctor tells you to.
Do not give your medicine to anyone else, even if they have the same condition as
Do not stop using your medicine or change the dose without checking with your doctor.
Zidoval is for vaginal use only. Do not use it in any other way.
Things to be careful of
Zidoval Vaginal Gel contains ingredients that may cause burning and irritation of
the eye. If you accidentally get Zidoval in your eye, rinse the eye immediately with
plenty of cool tap water.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you
are using Zidoval.
All medicines can have side effects. Sometimes they are serious, most of the time
they are not. You may need medical attention if you get some of the side effects.
Do not be alarmed by the following list of side effects. You may not experience any
Ask your doctor or pharmacist to answer any questions you may have.
Tell your doctor or pharmacist if you notice any of the following and they worry you:
abnormal vaginal discharge
itching, burning or swelling in or around the vagina
a feeling of increased pressure in the pelvic area
stomach cramp or pain
feeling sick or vomiting
diarrhoea (loose stools)
stomach bloating (gas)
feeling thirsty, dry mouth
skin itch or rash
Tell your doctor or pharmacist if you notice anything that is making you feel unwell.
Other side effects not listed above may also occur in some people.
After using Zidoval Vaginal Gel
Keep your tube of Zidoval gel and the vaginal applicators together in their box until
it is time to use them.
Keep your pack of Zidoval in a cool dry place where the temperature stays below 25°C.
Exposure to extreme heat or cold can spoil the gel.
Keep it where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place
to store medicines.
If your doctor tells you to stop using this medicine or the expiry date has passed,
ask your pharmacist what to do with any medicine that is left over.
What it looks like
Zidoval is a colourless to straw-coloured gel, contained in an aluminium tube.
Each tube contains 40g of Zidoval Vaginal Gel.
Each 5 g of Zidoval Vaginal Gel (one full applicator) contains 37.5 mg of metronidazole
as the active ingredient.
Zidoval is supplied by:
iNova Pharmaceutical (Australia) Pty. Limited
Level 10, 12 Help St
Chatswood, NSW 2067
Telephone: Toll free 1800 630 056
This leaflet was prepared in March 2017
AUST R 73743