Ankylosing Spondylitis Prognosis

Ankylosing spondylitis is a complex chronic disease that causes inflammation in the spine and other areas of the body. Symptoms of the condition develop gradually over months or years. Some individuals can eventually get better, while others find their condition deteriorates. Although patients are at risk of long-term disability, this can usually be prevented with exercise, physiotherapy and medication.

In around 70 to 90% of cases, independence is maintained and people only develop minimal disability. However, in some individuals, damage caused by inflammation in the spine and joints eventually causes severe disability and immobility.


Some examples of the complications associated with this disease are described below.

  • Although most people with this condition do not develop long-term disability, around 40% of individuals will eventually find movement is restricted in their spine. This occurs because bones in the lower part of the spine fuse, leading to a fixed, inflexible posture. In very severe cases, surgery may be recommended to help resolve the problem.
  • Osteoporosis can develop in the spine and other bones of the body, which are then prone to fracture. The risk of osteoporosis increases the longer a person has ankylosing spondylitis. A number of medications are available to help increase bone strength in those who develop osteoporosis.
  • Ankylosing spondylitis causes inflammation in joints such as the hips and knees, which can eventually become damaged, making it difficult and painful to move. Again, surgery may be recommended to replace the joint in severe cases.
  • People with ankylosing spondylitis are at an increased risk of developing cardiovascular complications such as heart disease or stroke. People with this condition should therefore follow guidelines to help minimize their risk of cardiovascular disease. Some examples of lifestyle changes include stopping smoking, losing weight, dietary changes to lower blood pressure and engaging in regular physical activity.
  • A condition called iritis or anterior uveitis can also develop, which causes one eye to become red, painful, swollen and sensitive to light. Vision may also become blurred. The condition can usually be treated using eye drops that contain a corticosteroid.

Further Reading

Last Updated: Jul 14, 2023

Dr. Ananya Mandal

Written by

Dr. Ananya Mandal

Dr. Ananya Mandal is a doctor by profession, lecturer by vocation and a medical writer by passion. She specialized in Clinical Pharmacology after her bachelor's (MBBS). For her, health communication is not just writing complicated reviews for professionals but making medical knowledge understandable and available to the general public as well.


Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    Mandal, Ananya. (2023, July 14). Ankylosing Spondylitis Prognosis. News-Medical. Retrieved on July 16, 2024 from

  • MLA

    Mandal, Ananya. "Ankylosing Spondylitis Prognosis". News-Medical. 16 July 2024. <>.

  • Chicago

    Mandal, Ananya. "Ankylosing Spondylitis Prognosis". News-Medical. (accessed July 16, 2024).

  • Harvard

    Mandal, Ananya. 2023. Ankylosing Spondylitis Prognosis. News-Medical, viewed 16 July 2024,


The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical.
Post a new comment

While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.

Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles.

Please do not ask questions that use sensitive or confidential information.

Read the full Terms & Conditions.