Life Science Articles

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Mitochondria Overview

Mitochondria are double membrane bound cytoplasmic organelles present in most eukaryotic cells. They are responsible for aerobic respiration, which they achieve through oxidative phosphorylation.

10 Apr 2018

What are Exosomes?

Exosomes are vesicles, or cellular components, that exist outside of a cell.

9 Apr 2018

Tunable Resistive Pulse Sensing Applications

Tunable resistive pulse sensing is used in single particle analysis to provide quantitative measurements that can be used in biology and nanotechnology.

9 Apr 2018

Immunoenzymatic Chromogen Staining

Immunoenzymatic staining of biological samples has grown to become a valuable tool for research and diagnostic purposes.

9 Apr 2018

Single Particle Analysis Techniques

For single particle analysis, electron microscopy is critical, processing techniques allow the structure of a single molecule or compound to be elucidated.

6 Apr 2018

What is Real-Time Quantitative PCR (qPCR)?

PCR is a commonly used method for amplifying DNA, which can then be used for gene cloning, sequencing, and for gene manipulation

5 Apr 2018

What is DNA Loop Extrusion?

DNA loop extrusion is a method used to analyze how DNA is compacted into the nucleus whilst bringing regulatory elements close to protein coding genes.

4 Apr 2018

History and Advances of X-Ray Microscopy

A pioneer once described the history of the X ray microscope as a “story of spies, heroes, villains, false starts, and a brush with real fame”.

4 Apr 2018

Applications of FISH

Fluorescence in situ hybridization (FISH) is a genetic technique used to diagnose congenital diseases, infectious disease and cancer.

3 Apr 2018

Lipid Peroxidation

Lipid peroxidation is a metabolic process that causes oxidative deterioration of lipids by reactive oxygen species.

2 Apr 2018

TP53 as a Tumor Suppressor

P53, the gene product of the TP53 gene, is a fundamental protein involved in the suppression of tumorigenesis.

2 Apr 2018

Tunable Resistive Pulse Sensing

Tunable resistive pulse sensing (TRPS) is a method used to provide quantitive size measurements in single particle analysis.

29 Mar 2018

Manipulating RNA sequences using CRISPR-Cas13

Recent advances in CRISPR-Cas13 technology mean that it can now be used to locate and even reduce cancer associated gene expression.

29 Mar 2018

What is TP53?

The TP53 is a gene that instructs the cell to produce tumor protein (p53), a vital transcription factor and tumor suppressor.

29 Mar 2018

What is Active Transport?

Active transport is the process of moving molecules across a cellular membrane through the use of cellular energy.

28 Mar 2018

Small Molecule Microarrays for Drug Discovery

Small molecule microarrays allow screening of biomolecules such as peptides and carbohydrates.

28 Mar 2018

What is B-Raf?

B-Raf is a protein encoded by the BRAF gene and is involved in the RAS/MAPK pathway, which regulates cellular growth and division.

28 Mar 2018

Leptin Signal Pathway

Leptin is a hormone is produced in adipocytes that acts on the brain to regulate endocrine functions and control energy expenditure.

26 Mar 2018

Rous Sarcoma Virus (RSV)

The discovery of the Rous Sarcoma Virus was the first demonstration that a malignant tumor could be caused by an infection.

26 Mar 2018

Functions of MHC in the Immune System

The major histocompatibility complex (MHC) is a group of genes that encode proteins on the cell surface that have an important role in immune response.

23 Mar 2018