Life Science Articles

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History and Advances of X-Ray Microscopy

A pioneer once described the history of the X ray microscope as a “story of spies, heroes, villains, false starts, and a brush with real fame”.

4 Apr 2018

Applications of FISH

Fluorescence in situ hybridization (FISH) is a genetic technique used to diagnose congenital diseases, infectious disease and cancer.

3 Apr 2018

Lipid Peroxidation

Lipid peroxidation is a metabolic process that causes oxidative deterioration of lipids by reactive oxygen species.

2 Apr 2018

TP53 as a Tumor Suppressor

P53, the gene product of the TP53 gene, is a fundamental protein involved in the suppression of tumorigenesis.

2 Apr 2018

Tunable Resistive Pulse Sensing

Tunable resistive pulse sensing (TRPS) is a method used to provide quantitive size measurements in single particle analysis.

29 Mar 2018

Manipulating RNA sequences using CRISPR-Cas13

Recent advances in CRISPR-Cas13 technology mean that it can now be used to locate and even reduce cancer associated gene expression.

29 Mar 2018

What is TP53?

The TP53 is a gene that instructs the cell to produce tumor protein (p53), a vital transcription factor and tumor suppressor.

29 Mar 2018

What is Active Transport?

Active transport is the process of moving molecules across a cellular membrane through the use of cellular energy.

28 Mar 2018

Small Molecule Microarrays for Drug Discovery

Small molecule microarrays allow screening of biomolecules such as peptides and carbohydrates.

28 Mar 2018

What is B-Raf?

B-Raf is a protein encoded by the BRAF gene and is involved in the RAS/MAPK pathway, which regulates cellular growth and division.

28 Mar 2018

Leptin Signal Pathway

Leptin is a hormone is produced in adipocytes that acts on the brain to regulate endocrine functions and control energy expenditure.

26 Mar 2018

Rous Sarcoma Virus (RSV)

The discovery of the Rous Sarcoma Virus was the first demonstration that a malignant tumor could be caused by an infection.

26 Mar 2018

Functions of MHC in the Immune System

The major histocompatibility complex (MHC) is a group of genes that encode proteins on the cell surface that have an important role in immune response.

23 Mar 2018

What are Viral Retroposons?

Retroposons are repetitive DNA fragments that are inserted into a host chromosome after reverse transcription from an RNA molecule.

23 Mar 2018

Regulation of JAK/STAT Signalling

The JAK/STAT signalling pathway controls the activity of various cytokines and growth factors. It regulates hematopoiesis, adipogenesis, and development.

21 Mar 2018

Gram Positive Bacteria

Gram positive bacteria are those that stain purple. They are usually non-pathogenic and their cell walls contain a thick layer of peptidoglycan.

21 Mar 2018

What is Satellite DNA?

Satellite DNA consists of arrays of tandemly repeating sequences that are widely present in the human genome.

19 Mar 2018

What is Genetic Anticipation?

Genetic anticipation is a phenomenon in which the symptoms of a genetic condition worsen between generations.

19 Mar 2018

Tumor Suppressor Genes

Tumor suppressor genes have an important role in the prevention of cancer. Functioning tumor suppressor genes encode proteins which inhibit tumor growth.

16 Mar 2018