"Insights from Industry" is a dynamic series of interviews at the cutting edge of the life sciences industry.
Every interviewee is a leader in their particular field and is handpicked to give an informative and accessible
insight into their chosen field. These interviews are guaranteed to keep you in the know in a rapidly changing industry.
Traditional light microscopy techniques such as confocal and wide-field are diffraction-limited in resolution, which is about 200 nm laterally (in xy) and 500 to 600 nm axially (in z). Features that are closer than the diffraction limit will appear blurred in the image.
Illumina sees a widespread demand for genotyping products and a continued relevance of arrays in human disease and translational research.
Specialty pharmaceuticals as a category has its origins in the 1970s with complex treatments being developed for disease areas such as cancer, HIV and haemophilia and what characterises a specialty pharmaceutical product is that it will be high touch, high complexity or high cost and is often associated with the treatment of rare or orphan conditions. These products require a considerable amount of expertise, innovation and technology and can be expensive as a result.
In developing antisense therapeutics, scientists at Ionis evaluate thousands of oligonucleotides. One of my responsibilities is to oversee the QC and management of oligonucleotides used in target screening.
BioScope Resolve has enabled the first AFM images resolving individual microvilli on live cells. This is remarkable in that atomic force microscopy has been widely used to image live cells, and microvilli are often present. Yet the surface of those cells had remained featureless in AFM images.
Alex Cooper from Sutter Instrument discusses how spectral imaging technologies can be used in a wide range of microscopy applications.
Microplate readers are divided into single-mode and multi-mode readers. A single mode reader is mainly a reader dedicated to the detection of absorbance, luminescence or fluorescence.
Extracellular vesicles are membrane surrounded structures released by cells in an evolutionally conserved manner. There are three main types of EVs, Exosomes (50-100 nm), Microparticles (200 nm-1 um) and Apoptotic bodies.
The Genevac Series 1 System, which was launched in the mid 1990s, had no programming as such. It was a very basic system – it had basic vacuum control and a timer of sorts. It was very similar to the current myVac evaporator system we use for molecular biology and biological applications.
Whether prescribing or dispensing drugs to patients, or providing care to patients who are taking medications, drug information plays an essential role in every health professional’s busy day.
Spectrophotometry quantifies the concentration of a specific substance that is present in a sample by comparing the amount of light that goes into a sample versus the amount of light that comes out of the sample at a specific wavelength.
There are two types of protection, sample protection keeps the sample away from contaminants in the air; and operator protection, which protects the scientist from harm from whatever they’re working on
The ability to image the brain, so that it can be visualized and shared, is crucial to revolutionizing neuroscience research. Even a few years ago, what we’re able to do today wasn’t possible. The combination of being able to digitize whole mount slides and the availability of low cost storage and computer horsepower that has helped to make that a reality.
The mass spectrometer is a gas analyser capable of measuring every component in the bioreactor off-gas. This tells the control system if the bioreactor is operating at peak efficiency, or if changes need to be made to the operating conditions within the vessel.
We are very interested in accessing innovation and technology, but we can't hope to do everything ourselves. One way for us to do this is to set up the Innovation Village, to provide space for entrepreneurs and innovators in South Wales.
MicroCT (micron-scale computed tomography) technology was completely unknown when it began to be commercially available more than 15 years ago....
Liquid Nitrogen has many uses and applications beyond that of the medical and life sciences. In addition to dermatological use, biological specimen and embryo preservation, our customers use the Elan2 for cooling the outer jackets of MRI systems, semiconductor radiation detector cooling, infrared detector cooling and cryogenic annealing of metals.
Nanoparticle technology was originally developed in the 1980s and 1990s. As the technology evolved, it soon became possible to produce uniform nanoscopic beads that are magnetic, and that also have a variety of specific surface chemistries. It was immediately evident that such beads could be used to great advantage for biochemical separations.
Traditional manual pipettes are easy to operate, very affordable but limited regarding throughput. Laboratory robots offer fast, automated pipetting but require time to program, set up and come at a much higher price tag.
RNA guided CRISPR nucleases have a great potential for genome modification in many different organisms.