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Using CRISPR To Produce Induced Pluripotent Stem Cells

An interview with Dr. Sheng Ding about using a modified version of the CRISPR-Cas9 system to produce induced pluripotent stem cells.

9 Feb 2018

Gene expression is rhythmic in most tissue types

Researchers have mapped primate gene expression throughout the day and discovered that the majority of critical gene activity is time dependent, which may aid the development of new treatments for many diseases.

9 Feb 2018

Scientists develop ultrasound-propelled nanomotors for active delivery of Cas9-sgRNA complex

In cancer research, the “Cas-9–sgRNA” complex is an effective genomic editing tool, but its delivery across the cell membrane to the target (tumor) genome has not yet been satisfactorily solved. American and Danish scientists have now developed an active nanomotor for the efficient transport, delivery, and release of this gene scissoring system.

9 Feb 2018

Abzena selects Sartorius Stedim Biotech as preferred equipment supplier in the U.S

Abzena plc, the life sciences group providing services and technologies to enable the development and manufacture of biopharmaceutical products, has selected Sartorius Stedim Biotech as its preferred equipment supplier in the U.S.

From Sartorius 9 Feb 2018

Genevac’s HCl-resistant EZ-2 evaporator offers reliable sample preparation for neonatal screening

Genevac reports on how its hydrochloric acid (HCl) resistant EZ-2 evaporator offers significant benefits to clinical labs tasked with analyzing plasma, blood or urine samples for neonatal disorders.

9 Feb 2018

Researchers develop safe, potent mRNA vaccine adjuvants that can elicit effective immune response

Production of conventional vaccines, which involves the use of live-attenuated or purified protein subunits of pathogens, is a long and complex process. Nucleic acid vaccines are safer alternatives, and allow easy adjustment of antigen to target specific pathogens.

9 Feb 2018

DNA plays unexpected architectural role in shaping cells, study finds

As a basic unit of life, the cell is one of the most carefully studied components of all living organisms. Yet details on basic processes such as how cells are shaped have remained a mystery.

8 Feb 2018

Scientists design new triple labeling technique to analyze stem cell division

A joint team of scientists from Russia and the United States designed a method for marking dividing stem cells with three different labels.

8 Feb 2018

Compounds isolated from rattlesnake's venom show promise to fight against hepatitis C

A group of Brazilian scientists achieved promising results using isolated compounds from the venom of the South American rattlesnake in combat of hepatitis C.

8 Feb 2018

New family of peptides in wasp's venom may help develop better Parkinson's treatments

After being stung by a parasitic wasp, the American cockroach loses control of its behavior, becoming host to the wasp's egg.

8 Feb 2018

Researchers test effectiveness of investigational drug in treating diastolic dysfunction of the heart

Researchers at the University of Colorado School of Medicine have identified a potential treatment target for patients with a common type of heart failure.

8 Feb 2018

Scientists identify special pair of RNA scissors with many functions

CRISPR/Cas systems are known as promising "gene scissors" in the genome editing of plants, animals, and microorganisms by targeting specific regions in their DNA - and perhaps they can even be used to correct genetic defects.

8 Feb 2018

Researchers solve crystal structure for enzyme that plays key role in DNA methylation

A research team led by a biochemist at the University of California, Riverside has solved the crystal structure for an enzyme that plays a key role in DNA methylation, the process by which methyl groups are added to the DNA molecule.

7 Feb 2018

First drug-candidate compounds discovered using AI licensed for development

Insilico Medicine, Inc., a Baltimore-based next-generation artificial intelligence company specializing in the application of deep learning for drug discovery, announces that Juvenescence.AI, its joint venture with Juvenescence Limited, has licensed its first compound family for clinical development.

7 Feb 2018

IU scientists take important step to fight against hepatitis B with 'virus-cracking' molecules

Indiana University researchers have made an important step forward in the design of drugs that fight the hepatitis B virus, which can cause liver failure and liver cancer.

7 Feb 2018

Novel technology platform for custom designing bacteriophages

Bacteriophages, known informally as phages, are viruses that can attack and kill specific bacteria. They occur everywhere in the natural world. Precisely because they are matched to just one specific type of bacteria, researchers and medics hope that phages can be engineered to combat certain bacterial infections.

7 Feb 2018

Previously discarded antibiotic compounds could become life-saving drugs

Researchers are re-examining antibacterial compounds to see whether they could hold the key to fighting drug-resistant infections.

7 Feb 2018

Study sheds light on Salmonella death at low temperatures

The most economical way to kill bacteria that cause common food-borne illnesses -- mostly caused by Salmonella enterica -- is heat, but, the mechanisms that kill Salmonella at lower temperatures were not fully understood until now, according to a team of researchers.

7 Feb 2018

UIC scientists identify new chemical compound to stop bacteria from causing sickness

A study published in the Journal of Biological Chemistry is the first to describe a signaling pathway that affects communication -- a process called quorum sensing -- between Streptococcus bacteria cells.

6 Feb 2018

Open Pharma drug discovery project aims to develop new treatments for mycetoma

The MycetOS project was launched today by the University of Sydney, Erasmus MC, and the Drugs for Neglected Diseases initiative to use an Open Pharma approach to discover compounds that could lead to new treatments for patients suffering from fungal mycetoma (eumycetoma), a devastating disease for which current treatments are ineffective, expensive, and toxic.

6 Feb 2018

Life Science News

Using CRISPR To Produce Induced Pluripotent Stem Cells

Gene expression is rhythmic in most tissue types

Scientists develop ultrasound-propelled nanomotors for active delivery of Cas9-sgRNA complex

Abzena selects Sartorius Stedim Biotech as preferred equipment supplier in the U.S

Genevac’s HCl-resistant EZ-2 evaporator offers reliable sample preparation for neonatal screening

Researchers develop safe, potent mRNA vaccine adjuvants that can elicit effective immune response

DNA plays unexpected architectural role in shaping cells, study finds

Scientists design new triple labeling technique to analyze stem cell division

Compounds isolated from rattlesnake's venom show promise to fight against hepatitis C

New family of peptides in wasp's venom may help develop better Parkinson's treatments

Researchers test effectiveness of investigational drug in treating diastolic dysfunction of the heart

Scientists identify special pair of RNA scissors with many functions

Researchers solve crystal structure for enzyme that plays key role in DNA methylation

First drug-candidate compounds discovered using AI licensed for development

IU scientists take important step to fight against hepatitis B with 'virus-cracking' molecules

Novel technology platform for custom designing bacteriophages

Previously discarded antibiotic compounds could become life-saving drugs

Study sheds light on Salmonella death at low temperatures

UIC scientists identify new chemical compound to stop bacteria from causing sickness

Open Pharma drug discovery project aims to develop new treatments for mycetoma

Discovering a molecule that could replicate SARS-CoV-2

Providing Personalized Care for Bleeding Disorders

Delayed immune responses may be responsible for COVID-19 mortality rates

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