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Small molecules designed to inhibit activity of enzymes in infectious diseases

A multidisciplinary study by the Computer Biochemistry Research Group of the Universitat Jaume I from Castellón, Spain, in collaboration with groups from universities from Canada and the United Kingdom, have designed small molecules that are able to bond with and inhibit the activity of enzymes in infectious diseases.

8 Nov 2018

One type of Chlamydia protein manipulates human cells in two different ways

When Chlamydia trachomatis, the bacterium that causes one of the most common sexually transmitted infections worldwide, infects a human cell, it hijacks parts of the host to build protective layers around itself.

8 Nov 2018

Researchers develop technique to disrupt communication between microorganisms

The World Health Organization considers Pseudomonas aeruginosa a germ requiring urgent action to prevent and control its spread. The bacteria can cause a variety of diseases from chronic lung infections to sepsis.

8 Nov 2018

CWRH/UH researcher receives grant to study role of KLF2 factor in vascular-related disorders

Transcription factors are proteins that determine whether specific genes are transcribed or not by binding to DNA. In other words, they help turn genes "on" or "off."

8 Nov 2018

New research to understand fundamental role of ubiquitin in cell death or survival

An effective regulation of programmed cell death is crucial for the correct development of embryos, a working innate immune system, and the prevention of cancer. How cells control the switch between cell survival and death, and which signaling pathways are involved, remain unclear.

8 Nov 2018

New nano-immunotherapy promotes long-term acceptance of transplanted organs

Researchers at the Mount Sinai School of Medicine have developed a new nanotechnology-based immunotherapy that promotes long-term transplant acceptance in an animal model.

7 Nov 2018

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Melbourne scientists have discovered how tumor development is driven by mutations in the most important gene in preventing cancer, p53.

7 Nov 2018

Tracking down microRNA candidates linked to disease

What started as Ninad Oak's side project turned out into something much larger, his doctorate thesis. "The project started as my qualifying exam that I proposed at the end of my first year of graduate school," said Oak, a graduate student in molecular and human genetics in Dr. Sharon E. Plon's lab. "This was an off topic qualifying exam at the time, meaning the lab had not worked on this topic before."

7 Nov 2018

Scientists discover new details about UHRF1 protein

Epigenetic changes often play an important role in cancer, because they cause the genetic material to be read incorrectly at certain locations. Genes that are especially critical are those that control the growth and death of cells.

7 Nov 2018

Scientists investigate how broad-spectrum antibiotic therapy affects interaction of gut bacteria

The human gut is teeming with billions of beneficial bacteria. Therapies that use antibiotics often destroy most of them.

7 Nov 2018

Geneticists decipher new gene responsible for rare form of hair loss

Hypotrichosis simplex leads to progressive hair loss already in childhood. A team of researchers led by human geneticists at the University Hospital of Bonn has now deciphered a new gene that is responsible for this rare form of hair loss.

6 Nov 2018

MuVi SPIM light-sheet technology released by Bruker for imaging optically cleared samples

At the 2018 Annual Meeting of the Society for Neuroscience, Bruker announced the release of the Luxendo MuVi SPIM CS light-sheet fluorescence microscope for imaging optically cleared samples.

From Bruker Nano Surfaces 6 Nov 2018

Accelerating adoption of artificial intelligence-powered image search and whole slide scanning workflows

Huron announces it will accelerate the deployment of digital pathology workflows in hospitals and research/educational facilities.

From Huron Digital Pathology 6 Nov 2018

‘Incredible 2020’ initiative unveiled by ATCC at Neuroscience 2018

Reinforcing its long-established reputation for quality and reliability as the steward for credible biomaterial and standards in the biological sciences, ATCC today announced details of its new initiative, Incredible 2020.

5 Nov 2018

Multiphoton microscope for neurobiology applications introduced by Bruker

At the 2018 Annual SfN meeting, Bruker announced the release of the Ultima 2Pplus next-generation multiphoton, all-optical stimulation and simultaneous imaging platform for neurobiology applications.

From Bruker Nano Surfaces 5 Nov 2018

Researchers find cognitive changes in offspring of rats exposed to high cannabis concentrations

A study conducted by researchers at Washington State University has found changes in cognitive ability among the offspring of rats exposed to high amounts of cannabis during pregnancy.

5 Nov 2018

VTT, Dyadic to present data highlighting achievements in development of fungal production platform

VTT and Dyadic International, Inc., today announced that VTT scientists will present the excellent results in their collaboration over the past two years at two international conferences: AAPS PharmSci on November 7th in Washington DC and PEGS Europe on November 14th in Lisbon.

5 Nov 2018

Genetic inhibition of SARM1 prevents axonal degeneration in nervous systems

Disarm Therapeutics, a biotechnology company creating a new class of disease-modifying therapeutics for patients with axonal degeneration, a central driver of neurological disease, today announced data demonstrating that genetic inhibition of SARM1 prevents axonal degeneration in the central, ocular and peripheral nervous systems.

5 Nov 2018

New research explains how large virus shells are formed

A virus, the simplest physical object in biology, consists of a protein shell called the capsid, which protects its nucleic acid genome -- RNA or DNA. The capsid can be cylindrical or conical in shape, but more commonly it assumes an icosahedral structure, like a soccer ball.

5 Nov 2018

Horizon Discovery collaborates with Biocartis to offer reference standards for new Idylla MSI assay

Horizon Discovery Group plc, a global leader in gene editing and gene modulation technologies, today announces that it has developed a set of precisely defined cell line-derived reference standards to support Biocartis’ recently launched Idylla™ microsatellite instability Assay.

From Horizon Discovery 5 Nov 2018

Life Science News

Small molecules designed to inhibit activity of enzymes in infectious diseases

One type of Chlamydia protein manipulates human cells in two different ways

Researchers develop technique to disrupt communication between microorganisms

CWRH/UH researcher receives grant to study role of KLF2 factor in vascular-related disorders

New research to understand fundamental role of ubiquitin in cell death or survival

New nano-immunotherapy promotes long-term acceptance of transplanted organs

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Tracking down microRNA candidates linked to disease

Scientists discover new details about UHRF1 protein

Scientists investigate how broad-spectrum antibiotic therapy affects interaction of gut bacteria

Geneticists decipher new gene responsible for rare form of hair loss

MuVi SPIM light-sheet technology released by Bruker for imaging optically cleared samples

Accelerating adoption of artificial intelligence-powered image search and whole slide scanning workflows

‘Incredible 2020’ initiative unveiled by ATCC at Neuroscience 2018

Multiphoton microscope for neurobiology applications introduced by Bruker

Researchers find cognitive changes in offspring of rats exposed to high cannabis concentrations

VTT, Dyadic to present data highlighting achievements in development of fungal production platform

Genetic inhibition of SARM1 prevents axonal degeneration in nervous systems

New research explains how large virus shells are formed

Horizon Discovery collaborates with Biocartis to offer reference standards for new Idylla MSI assay

International Day of Action for Women’s Health: An Interview with Dame Claire Bertschinger

International Day of Action for Women’s Health: An Interview with UN Women

Asthma Awareness: Fighting Asthma in 2021

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