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Preclinical studies show effectiveness of targeted therapy for glioblastoma

The targeted therapy onalespib has shown effectiveness in preclinical studies of glioblastoma by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

2 Nov 2017

Researchers analyze molecular processes that influence aging

Understanding the factors that control aging has been one of humanity's endless pursuits, from the mystical fountain of youth to practical healthful regimens to prolong life expectancy.

2 Nov 2017

Scientists develop bioluminescent enzymatic test system for assessing toxicity of nanomaterials

Official website of the Russian Science Foundation reports that a group of scientists from Siberian Federal University and Krasnoyarsk Scientific Center of the SB RAS has developed a bioluminescent enzymatic test system for assessing the toxicity of carbon nanomaterials.

2 Nov 2017

Livecyte™ Cell Imaging and Analysis system adopted by the Translational Research Institute, Australia

The Translational Research Institute (TRI), Brisbane has become the first centre in Australia and the Asia Pacific region to adopt the Livecyte™ Cell Imaging and Analysis system.

From Phasefocus 1 Nov 2017

Natural-shaped plastic nanoparticles could improve delivery of toxic drugs to tumors

UNSW Sydney scientists have developed a way to control the shape of polymer molecules so they self-assemble into non-spherical nanoparticles - an advance that could improve the delivery of toxic drugs to tumors.

1 Nov 2017

Repositive introduces first Global PDX Directory at AACR conference

The first Global PDX Directory for proprietary and open source PDX models is being introduced by Cambridge (UK) based benefit corporation, Repositive, at the American Association for Cancer Research’sInternational Conference, on Molecular Targets and Cancer Therapeutics, hosted in conjunction with the European Organisation for Research and Treatment of Cancer and the National Cancer Institute, in Philadelphia, USA, 26-30 October 2017.

1 Nov 2017

Neutron crystallography study could open avenues for new drugs to battle diseases

Scientists at the Department of Energy’s Oak Ridge National Laboratory have performed neutron structural analysis of a vitamin B6-dependent protein, potentially opening avenues for new antibiotics and drugs to battle diseases such as drug-resistant tuberculosis, malaria, and diabetes.

1 Nov 2017

Tiny microscopes give researchers a peek into neural circuitry of social behavior

Tiny microscopes mounted on mice's heads have given researchers a peek into the neural circuitry of social behavior.

1 Nov 2017

Powerful toolkit uncovers rare tumor suppressor genes

A new statistical model has enabled researchers to pinpoint 27 novel genes thought to prevent cancer from forming, in an analysis of over 2000 tumors across 12 human cancer types. The findings could help create new cancer treatments that target these genes, and open up other avenues of cancer research.

31 Oct 2017

Studying the nanomechanical properties of aging and cancerous cells using AFM

Force microscopy is a technique which would probably be best described with the help of a small finger with an apex just a few atoms in size that can touch objects. This is a learning finger.

From Bruker Nano Surfaces 31 Oct 2017

NASA’s “Twins Study” explores the effects space travel has on the human body

Preliminary results from NASA’s Twins Study have revealed some of the bodily changes that occurred in an astronaught, who spent almost one year in space, compared with his twin brother, who remained on earth.

30 Oct 2017

Inner workings of cells probed by new Kleindiek nanomanipulator at UNSW

The mechanism of how cells work is key to understanding how tumours metastasize as well as tissue regeneration and other bodily functions. The process of mechanotransduction, or how a cell converts a physical stimuli into an electrical response is fundamental to these understandings.

From AXT Pty Ltd 30 Oct 2017

UC study reveals metamorphic adaptation of certain spadefoot toads in response to climate change

Deep within aquatic ecosystems all over the world, certain toad species have managed to survive warmer and drier climate change. But the method behind their metamorphic adaptation to environmental change over time has long puzzled scientists -- until now.

28 Oct 2017

Longevity Biotech receives award to evaluate novel drug candidate for MS in preclinical models

Longevity Biotech, Inc. has received an award from the National Multiple Sclerosis Society through Fast Forward, the Society's commercial research funding program, to evaluate LBT-3627 in preclinical models as a potential disease-modifying therapeutic agent.

28 Oct 2017

Chinese scientists establish synthesis of promising compound to fight against pancreatic cancer

Intriguing antitumor activity is found in a very promising class of natural compounds: cyclic depsipeptides, which have a challenging structure that makes their investigation difficult. Now, Chinese scientists have established the synthesis of a member compound, which is especially promising in killing pancreatic cancer stem cells.

28 Oct 2017

Novel consortium aims to create new paradigm of cancer drug discovery

Scientists from two U.S. national laboratories, industry and academia today launched an unprecedented effort to transform the way cancer drugs are discovered by creating an open and sharable platform that integrates high-performance computing, shared biological data from public and industry sources and emerging biotechnologies to dramatically accelerate the discovery of effective cancer therapies.

27 Oct 2017

New concise guide to pharmacology offers key information on major drug targets

The Concise Guide to PHARMACOLOGY 2017/18 is now available in the British Journal of Pharmacology. Published by Wiley on behalf of the British Pharmacological Society, the 440 page guide includes overviews of key properties for close to 1,700 human drug targets, identifies 3,500 ligands including more than 2,400 synthetic organic molecules and over 50 antibodies.

27 Oct 2017

Genome-wide molecular tests can guide treatment in recurrent glioblastoma, study shows

Several patients with recurring glioblastoma, a deadly brain cancer, survived for more than a year in a clinical trial believed to be the first to use comprehensive DNA and RNA sequencing of a patient's tumor to inform treatment for these patients in real-time.

27 Oct 2017

Digital Pathology for Everyone

There are two problems that pathologists face today. The first is, that a pathologist’s diagnosis using tissue sections is becoming more complex. There are many more biomarkers, and clinicians now ask for a more precise diagnosis. Secondly, the number of pathologists worldwide is declining every day, as the profession is often overlooked in favor of other specializations.

From microDimensions 27 Oct 2017

Researchers provide new insight into how nematode's brain controls movement

The human brain is a mysterious supercomputer. Billions of neurons buzz within an intricate network that controls our every thought, feeling, and movement. And we've only just begun to understand how it all works.

26 Oct 2017

Life Science News

Preclinical studies show effectiveness of targeted therapy for glioblastoma

Researchers analyze molecular processes that influence aging

Scientists develop bioluminescent enzymatic test system for assessing toxicity of nanomaterials

Livecyte™ Cell Imaging and Analysis system adopted by the Translational Research Institute, Australia

Natural-shaped plastic nanoparticles could improve delivery of toxic drugs to tumors

Repositive introduces first Global PDX Directory at AACR conference

Neutron crystallography study could open avenues for new drugs to battle diseases

Tiny microscopes give researchers a peek into neural circuitry of social behavior

Powerful toolkit uncovers rare tumor suppressor genes

Studying the nanomechanical properties of aging and cancerous cells using AFM

NASA’s “Twins Study” explores the effects space travel has on the human body

Inner workings of cells probed by new Kleindiek nanomanipulator at UNSW

UC study reveals metamorphic adaptation of certain spadefoot toads in response to climate change

Longevity Biotech receives award to evaluate novel drug candidate for MS in preclinical models

Chinese scientists establish synthesis of promising compound to fight against pancreatic cancer

Novel consortium aims to create new paradigm of cancer drug discovery

New concise guide to pharmacology offers key information on major drug targets

Genome-wide molecular tests can guide treatment in recurrent glioblastoma, study shows

Digital Pathology for Everyone

Researchers provide new insight into how nematode's brain controls movement

Studying the Proteome and Human Diseases using Mass Spectrometry

Creating a blood test for the detection of Alzheimer’s disease

Using medieval medicine to find new treatments for modern-day infections

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