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Defective mitochondrial DNA could be modified using gene-editing techniques

Defective mitochondria – the 'batteries' that power the cells of our bodies – could in future be repaired using gene-editing techniques.

8 Feb 2022

Compounds used to fight fungal diseases in plants may be driving antimicrobial resistance

New research from the University of Georgia has shown, for the first time, that compounds used to fight fungal diseases in plants are causing resistance to antifungal medications used to treat people.

8 Feb 2022

Regulatory sequences in the genomes of mammals help explain how cancer invades normal tissues

Researchers from UConn Heath and Yale University have made new advances connecting the evolution of pregnancy and cancer metastasis.

8 Feb 2022

New method decodes the role of DDX41 protein in preventing double-strand breaks in DNA

There are many different ways in which the genetic material DNA can be damaged, resulting in the development of diseases such as cancer. Certain forms of DNA damage are associated with so-called R-loops.

8 Feb 2022

Using sugar molecules for in vivo tracking of unlabeled stem cells

A Johns Hopkins Medicine scientist who spent 30 years figuring out how to put chemical labels into cells to track their movement in living tissues has found that certain self-renewing stem cells have built-in tracers - made out of sugars - that can do the job without added chemical "labels" when injected into mouse brains.

8 Feb 2022

Study uncovers a series of natural products that can inhibit the main protease of SARS-CoV-2

The fight against the COVID-19 pandemic is an international scientific challenge regarding the search for strategies to fight the viral infection and prevent its damaging consequences.

7 Feb 2022

Genetically informed brain atlases help identify hundreds of genomic loci

An international team of scientists has used atlases of the human brain informed by genetics to identify hundreds of genomic loci. Loci is plural for locus, and in genetics indicates the physical location of a gene or variant on a chromosome.

7 Feb 2022

Selenium could boost learning and memory in aging brains

Selenium – a mineral found in many foods – could reverse the cognitive impact of stroke and boost learning and memory in aging brains, according to University of Queensland research.

7 Feb 2022

Dopamine signaling promotes the development of compulsive reward seeking behavior

Northwestern investigators have discovered that dopamine signaling in the brain's dorsomedial striatum promotes the development of compulsive behaviors in animal models, according to findings published in Current Biology.

7 Feb 2022

Cocktail of two chemicals could help slow down age-related muscular decline

Researchers from Tokyo Metropolitan University have shown that a mixture of 5-aminolevulinic acid(5-ALA) hydrochloride and sodium ferrous citrate (SFC) helps slow down aging-related muscular decline in fruit flies, leading to a slower decline in locomotor activity and longer lifespans.

7 Feb 2022

Study identifies 29 new genetic variants linked to acne

A study of the genetics of acne has identified 29 regions of the genome that influence the condition. These genetic insights offer potential new targets for treatment. They may also help clinicians identify individuals at high risk of severe disease.

7 Feb 2022

USP22 crucial for type III interferon signaling and SARS-CoV-2 infection

In a recent study posted to the bioRxiv* pre-print server, a team of researchers demonstrated that ubiquitin-specific peptidase 22 (USP22) is a crucial regulator of basal interferon (IFN) signaling in native human intestinal epithelial cells (hIECs).

7 Feb 2022

Study provides key information about the mechanism of breast cancer progression

Breast cancer is the most common cancer in women worldwide, yet despite medical advances, a cure for the tumors that spread locally and especially to distant sites remains out of reach.

7 Feb 2022

Fast & efficient evaporator for chromatography solvents

Designed to provide dry down of samples in microplates and glass tubes up to 150 mm in length - the Ultravap® Mistral XT150 blowdown evaporator from Porvair Sciences offers a low maintenance, sample-safe alternative to using water bath-based evaporators.

From Porvair Sciences Limited 6 Feb 2022

Life Science News

Defective mitochondrial DNA could be modified using gene-editing techniques

Compounds used to fight fungal diseases in plants may be driving antimicrobial resistance

Regulatory sequences in the genomes of mammals help explain how cancer invades normal tissues

New method decodes the role of DDX41 protein in preventing double-strand breaks in DNA

Using sugar molecules for in vivo tracking of unlabeled stem cells

Study uncovers a series of natural products that can inhibit the main protease of SARS-CoV-2

Genetically informed brain atlases help identify hundreds of genomic loci

Selenium could boost learning and memory in aging brains

Dopamine signaling promotes the development of compulsive reward seeking behavior

Cocktail of two chemicals could help slow down age-related muscular decline

Study identifies 29 new genetic variants linked to acne

USP22 crucial for type III interferon signaling and SARS-CoV-2 infection

Study provides key information about the mechanism of breast cancer progression

Fast & efficient evaporator for chromatography solvents

Researchers discover a new function of anti-HIV-1 antibodies

A novel approach to predict mutations within the SARS-CoV-2 spike

Scientists reveal how droplets of transcription factors collectively read DNA regions to switch on genes

Genomes of marine invertebrates found to be surprisingly stable across deep time

Researchers investigate how messenger substances signal inflammation during damaged cell removal

Gene therapy helps heart muscle cells electrically activate in live mice

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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