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Study identifies a genetic mutation linked to high risk of lethal childhood leukemia

A genetic variant changing just one base pair of nucleotides greatly increases risk of a high-risk subtype of childhood acute lymphoblastic leukemia (ALL), according to a Northwestern Medicine study published in Nature Genetics.

3 Feb 2022

New method may be effective at quantifying DNA adenine methylation in complex organisms

For decades, a small group of cutting-edge medical researchers have been studying a biochemical, DNA tagging system, which switches genes on or off. Many have studied it in bacteria and now some have seen signs of it in, plants, flies, and even human brain tumors.

3 Feb 2022

CRISPRa method helps discover genes that play a role in immune cell biology

CRISPR genome editing has served as a powerful tool for deleting or altering DNA sequences and studying the resulting effect.

3 Feb 2022

Spice could play a key role in reducing salt intake among seniors

Montero, M.L., et al. (2022) Saltiness perception in white sauce formulations as tested in older adults. Food Quality and Preference. doi.org/10.1016/j.foodqual.2022.104529.

3 Feb 2022

Sample management of Covid-19 Cryobox tube racks

Ziath reports on the widespread adoption of its DataPaq™ Cube rack reader in Covid-19 testing labs for tracking of sample tubes cryogenically stored in cryoboxes.

3 Feb 2022

Nanoparticle vaccine effective against eight SARS-CoV-2 variants in non-human primates

Researchers demonstrate that SARS-CoV-2 RBD-based nanoparticle vaccine induces neutralizing antibodies against SARS-CoV-2 variants.

2 Feb 2022

Genome study reveals unexpected heterogeneity of human ribosomal RNA genes

A genome study undertaken by Johns Hopkins Kimmel Cancer Center researchers to look for variants in a gene considered a fundamental building block for microscopic structures that synthesize proteins took a surprising twist.

2 Feb 2022

Study offers unprecedented insight into the mechanism of action of topo VI enzyme

The function of an enzyme, critical to most forms of life, has been revealed.

2 Feb 2022

Study reveals a direct correlation between fat browning and consumption of flavan 3-ols

In cold conditions, brown adipose tissue (BAT) or brown fat generates heat to keep the body warm. Compared with white adipose tissue, BAT has more mitochondria - subcellular organelles associated with energy production - which allows it to burn calories and produce heat by activating the mitochondrial uncoupling protein 1 (Ucp-1).

2 Feb 2022

Three different autism risk genes found to have similar effects on brain development

Autism spectrum disorder has been associated with hundreds of different genes, but how these distinct genetic mutations converge on a similar pathology in patients has remained a mystery.

2 Feb 2022

UCLA researchers develop first human genomic transgenic mouse model of Huntington's disease

Researchers at the Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA and the David Geffen School of Medicine at UCLA have developed a new mouse model of Huntington's disease that recapitulates more Huntington's disease-like characteristics than earlier models.

2 Feb 2022

Study discovers how long-term memory T cells are formed after SARS-CoV-2 exposure

Exposure to SARS-CoV-2 by infection or vaccination generates immune cells that provide long-term immunity. These long-lived memory T cells play a key role in preventing severe cases of Covid-19. Researchers at the University of Zurich have now discovered how these memory T cells form.

2 Feb 2022

Researchers elucidate first 3D structure of regulator protein complex

Proteins are indispensable components in living organisms. They are not only "building material" for the body – they also make molecular communication between cells possible, they are needed for nerve impulses to occur, and they control chemical reactions.

2 Feb 2022

'Genetic scissors' can give rise to unforeseen heritable mutations

CRISPR-Cas9, the "genetic scissors", creates new potential for curing diseases; but treatments must be reliable. In a new study, researchers have discovered that the method can give rise to unforeseen changes in DNA that can be inherited by the next generation.

2 Feb 2022

Researchers discover mechanism behind loss of smell in people with COVID-19

Researchers have discovered a mechanism that may explain why people with COVID-19 lose their sense of smell.

2 Feb 2022

Rolling brain wave patterns can provide clue to understanding sleep, anesthesia, and attention

While sleeping, the entire brain rolls through long, slow waves of electrical activity, like waves on a calm ocean. Researchers call that state of consciousness "slow wave sleep".

2 Feb 2022

Study uncovers a class of microbial enzymes that drive ulcerative colitis

Ulcerative colitis, a subtype of inflammatory bowel disease, is a chronic ailment of the colon affecting nearly one million individuals in the United States. It is thought to be linked to disruptions in the gut microbiome - the bacteria and other microbes that live inside us - but no existing treatments actually target these microorganisms.

2 Feb 2022

Scientists describe a smell sensory map in fruit flies

The distinctive smell of a flower.. the unmistakable aroma of coffee… the dangers linked with inhaling smoke fumes. Sensory systems have evolved to provide us with immediate, finely tuned information about the world around us, whether they are colors processed through our visual system or certain pitches interpreted through our hearing.

2 Feb 2022

New nanoparticle SARS-CoV-2 vaccine shows stronger, broader, and more durable protection

The first generation of COVID-19 vaccines have been highly effective, but also have limitations: their efficacy can wane without a booster shot, and they may be less effective against some variants.

2 Feb 2022

Gut bacteria transfer genes through sex to take vitamin B12, study shows

Your gut bacteria need vitamin B12 just as much as you do. Though DNA is usually passed from parent to child, new research shows gut bacteria transfer genes through "sex" in order to take their vitamins.

2 Feb 2022

Life Science News

Study identifies a genetic mutation linked to high risk of lethal childhood leukemia

New method may be effective at quantifying DNA adenine methylation in complex organisms

CRISPRa method helps discover genes that play a role in immune cell biology

Spice could play a key role in reducing salt intake among seniors

Sample management of Covid-19 Cryobox tube racks

Nanoparticle vaccine effective against eight SARS-CoV-2 variants in non-human primates

Genome study reveals unexpected heterogeneity of human ribosomal RNA genes

Study offers unprecedented insight into the mechanism of action of topo VI enzyme

Study reveals a direct correlation between fat browning and consumption of flavan 3-ols

Three different autism risk genes found to have similar effects on brain development

UCLA researchers develop first human genomic transgenic mouse model of Huntington's disease

Study discovers how long-term memory T cells are formed after SARS-CoV-2 exposure

Researchers elucidate first 3D structure of regulator protein complex

'Genetic scissors' can give rise to unforeseen heritable mutations

Researchers discover mechanism behind loss of smell in people with COVID-19

Rolling brain wave patterns can provide clue to understanding sleep, anesthesia, and attention

Study uncovers a class of microbial enzymes that drive ulcerative colitis

Scientists describe a smell sensory map in fruit flies

New nanoparticle SARS-CoV-2 vaccine shows stronger, broader, and more durable protection

Gut bacteria transfer genes through sex to take vitamin B12, study shows

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Latest Life Science News