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Duke Human Vaccine Institute secures federal contract for advancing investigational vaccines

The National Institute of Allergy and Infectious Diseases awarded researchers at the Duke Human Vaccine Institute a contract that enables it to compete for projects advancing investigational vaccines to production for use in early clinical trials.

14 Dec 2021

Flawed genetic switches could be at the origin of malformations or developmental diseases

Embryonic development follows delicate stages: for everything to go well, many genes must coordinate their activity according to a very meticulous scheme and tempo. This precision mechanism sometimes fails, leading to more or less disabling malformations.

14 Dec 2021

Scientists describe dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Clinician scientists and scientists from the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore, in collaboration with Singapore General Hospital, the National University Health System, Duke-NUS Medical School, Nanyang Technological University, and collaborators from China, Malaysia, Thailand and the Philippines, have described a dynamic genomic landscape of tumour heterogeneity in hepatocellular carcinoma (HCC).

13 Dec 2021

Protein can protect the heart from damage following cancer treatment

Cancer treatment can be tough on the body, but for the patient to survive the cancer, it's often necessary to go through with the treatment anyway.

13 Dec 2021

Iota-carrageenan inhibits replication of SARS-CoV-2 VOCs

Scientists have recently reported the efficacy of carrageenan against both the SARS-CoV-2 original strain as well as the Alpha, Beta, Gamma, and Delta VOCs.

13 Dec 2021

Diversity in genetic data improves the ability to predict high cholesterol risk

Including data from people of diverse ancestries substantially improves certain genetic risk predictions in all populations, according to a study that examined the genes responsible for regulating blood cholesterol levels.

13 Dec 2021

New copper surface could help fight antibiotic-resistant superbugs

A new copper surface that kills bacteria more than 100 times faster and more effectively than standard copper could help combat the growing threat of antibiotic-resistant superbugs.

13 Dec 2021

Study demonstrates SARS-CoV-2 ORF6 localization and interferon antagonism as independent events

Researchers deploy mutagenesis studies to investigate the relationship between ORF6 localization and IFN antagonism.

12 Dec 2021

Statistical model builds SARS-CoV-2 interactome with miRNAs, protein-coding genes, and co-infecting microbes

A team of researchers recently developed a statistical modeling method known as multiple-layer crosstalk (MLCrosstalk).

12 Dec 2021

Effect of mutations on SARS-CoV-2 E protein interactions with cell junctions

In a recent study, ten human PDZ-containing proteins showed significant interactions with the SARS-CoV-2 E protein in a PBM-dependent manner.

12 Dec 2021

Study provides better understanding of the degenerative underpinnings of Parkinson’s disease

Northwestern investigators have discovered the molecular signature of a subset of dopaminergic neurons with an increased vulnerability to degeneration.

12 Dec 2021

Apterous protein plays a crucial double role in retaining memories, study reveals

Researchers from Tokyo Metropolitan University have gained insights into the biochemistry of long-term memory. Studying fruit flies, they found that the Apterous (Ap) protein plays a crucial double role in retaining memories.

12 Dec 2021

Researchers discover new mechanism behind the formation of membrane vesicles

Canadian and American researchers have discovered a new mechanism by which membrane vesicles are made. These self-contained nanoparticles trap proteins, RNA and other molecules from inside or outside of living cells as nutrients or regulate the numbers of cell surface hormone receptors, such as those for insulin, to control the sensitivity of cells to hormones.

10 Dec 2021

Insight into immune cell communication may pave the way for new cancer vaccines

In the past decade, immunotherapy has helped save the lives of many cancer patients, many with lung cancer, who might have otherwise faced almost certain death sentences.

9 Dec 2021

Johns Hopkins astrophysicist receives Life Sciences 2021 award for novel cancer mapping technology

Johns Hopkins astrophysicist, Alexander Szalay, Ph.D., and Kimmel Cancer Center pathologist Janis Taube, M.D., M.Sc., received a Life Sciences 2021 award for AstroPath at this year's Falling Walls Science Summit, an international event honoring research breakthroughs from across the globe.

9 Dec 2021

Higher intake of plant-based foods could help reduce the risk of cognitive decline due to aging

A diet rich in plant products reduces the risk of cognitive impairment and dementia in the elderly. This is the result of a study by the Biomarkers and Nutritional Food Metabolomics Research Group of the Faculty of Pharmacy and Food Sciences of the University of Barcelona and the CIBER on Frailty and Healthy Aging.

9 Dec 2021

Researchers recapitulate the human form of arrhythmogenic cardiomyopathy in zebrafish model

The research groups of Jeroen Bakkers (Hubrecht Institute/UMC Utrecht) and Toon van Veen (UMC Utrecht) bring forward the first patient-specific model for the heart disease arrhythmogenic cardiomyopathy (ACM).

9 Dec 2021

SARS-CoV-2 Omicron variant may bind with ACE2 receptor more efficiently

A new study discusses the effect of the Omicron variant’s mutations on its binding efficiency to the ACE2 receptor.

9 Dec 2021

Scientists determine structure of the molecule associated with ALS for the first time

Scientists have determined for the first time the structure of the molecule associated with amyotrophic lateral sclerosis (ALS) and multiple other neurodegenerative diseases.

9 Dec 2021

Private Label & Custom Manufactured Microplates

Drawing upon its expertise in polymer moulding, surface treatment, specialist assembly and knowledge of analytical, healthcare and life science applications has enabled Porvair Sciences to become a market leading supplier of private label and custom manufactured microplates.

From Porvair Sciences Limited 9 Dec 2021

Life Science News

Duke Human Vaccine Institute secures federal contract for advancing investigational vaccines

Flawed genetic switches could be at the origin of malformations or developmental diseases

Scientists describe dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Protein can protect the heart from damage following cancer treatment

Iota-carrageenan inhibits replication of SARS-CoV-2 VOCs

Diversity in genetic data improves the ability to predict high cholesterol risk

New copper surface could help fight antibiotic-resistant superbugs

Study demonstrates SARS-CoV-2 ORF6 localization and interferon antagonism as independent events

Statistical model builds SARS-CoV-2 interactome with miRNAs, protein-coding genes, and co-infecting microbes

Effect of mutations on SARS-CoV-2 E protein interactions with cell junctions

Study provides better understanding of the degenerative underpinnings of Parkinson’s disease

Apterous protein plays a crucial double role in retaining memories, study reveals

Researchers discover new mechanism behind the formation of membrane vesicles

Insight into immune cell communication may pave the way for new cancer vaccines

Johns Hopkins astrophysicist receives Life Sciences 2021 award for novel cancer mapping technology

Higher intake of plant-based foods could help reduce the risk of cognitive decline due to aging

Researchers recapitulate the human form of arrhythmogenic cardiomyopathy in zebrafish model

SARS-CoV-2 Omicron variant may bind with ACE2 receptor more efficiently

Scientists determine structure of the molecule associated with ALS for the first time

Private Label & Custom Manufactured Microplates

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

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