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New phenotype of LRP6 mutation reported for the first time in patients with tooth agenesis

A group led by Prof. Han Dong of Peking University School of Stomatology reported for the first time hand preaxial polydactyly in patients with tooth agenesis carrying a previously unknown mutation of low-density lipoprotein receptor-related protein 6 (LRP6).

29 Nov 2021

Novel approach uses PSOCT to non-invasively image the depth-resolved collagen organization

Collagen is essential for tissue integrity and stability, and changes in its intrinsic organization are the key features in several important diseases such as scar formation, heart infarction and cancers.

29 Nov 2021

Cytomegalovirus herpesvirus can accelerate the decline of the immune system, study finds

A research team at the University of Córdoba is studying the alterations that occur in the immune system's T lymphocytes with respect to age and in relation to the cytomegalovirus herpesvirus.

29 Nov 2021

Error rate of bacterial DNA polymerase is consistently higher under microgravity, study shows

On 22 May 2019, scientists from Queen's University boarded a modified Falcon 20 aircraft at Ottawa airport. Scheduled was a 'vomit comet' flight, where the plane repeatedly climbs to 8km in a steep parabola, alternating with a descent in freefall.

29 Nov 2021

The mode of action of essential proteins involved in cancer and Alzheimer´s deciphered

The proteins that belong to the HAT family are essential for life as they transport amino acids across the cell membrane. Although the members of this family are practically identical, some transport certain amino acids and not others.

29 Nov 2021

Rare variants in high-risk autism gene can alter architecture and organization of neurons, study finds

Scientists at the University of North Carolina at Chapel Hill School of Medicine and colleagues have demonstrated that rare variants in the ANK2 gene, consistently found in individuals with autism spectrum disorder (ASD), can alter architecture and organization of neurons, potentially contributing to autism and neurodevelopmental comorbidities.

29 Nov 2021

Biologists discover how a protein in our body works

It's an old needlework trick, and a protein in our body knows it: Instead of threading yarn into the eye from the end, it can be easier to pass a loop through it.

29 Nov 2021

Genetic variations affect and rewire phosphorylation signaling networks in SARS-CoV-2 infection

Researchers study human single nucleotide variants (SNVs) using machine learning to identify amino acid changes that alter kinase-bound sequence motifs.

29 Nov 2021

Simple change can maximize a single cell's production of extracellular vesicles

A simple change in the way donor cells are processed can maximize a single cell's production of extracellular vesicles, which are small nanoparticles naturally secreted by cells, according to new research from researchers at the University of Illinois Chicago.

29 Nov 2021

Tomosyn protein's key contribution to heterogeneity of neurons revealed

The versatility of the nervous system comes from not only the diversity of ways in which neurons communicate in circuits, but also their "plasticity," or ability to change those connections when new information has to be remembered, when their circuit partners change, or other conditions emerge.

29 Nov 2021

Study uncovers mechanism for insensitivity to key antimalarial drug in new pathogen variant

Malaria is one of the most dangerous infectious diseases. The causative pathogens are microorganisms of the genus Plasmodium.

29 Nov 2021

Researchers shed light on an important stage of early human embryogenesis for the first time

Scientists have shed light on an important stage of early embryonic development that has never been fully mapped out in humans before.

29 Nov 2021

Study reveals a previously unknown mechanism for pancreatic cancer metastasis

Pancreatic cancer is very aggressive and, unfortunately, has a poor prognosis with a 5-year survival of only 5%. Most deaths related to pancreatic cancer are due to metastasis, which occurs when the tumour invades other organs.

29 Nov 2021

Complex RNA structures could have untapped therapeutic potential in the fight against COVID-19

To the untrained eye, the loops, kinks and folds in the single strand of RNA that makes up the coronavirus genome look like a jumble of spaghetti or tangled yarn. But to researchers like Amanda Hargrove, a chemistry professor at Duke University, the complex shapes that RNA takes on as it folds upon itself could have untapped therapeutic potential in the fight against COVID-19.

26 Nov 2021

Life Science News

New phenotype of LRP6 mutation reported for the first time in patients with tooth agenesis

Novel approach uses PSOCT to non-invasively image the depth-resolved collagen organization

Cytomegalovirus herpesvirus can accelerate the decline of the immune system, study finds

Error rate of bacterial DNA polymerase is consistently higher under microgravity, study shows

The mode of action of essential proteins involved in cancer and Alzheimer´s deciphered

Rare variants in high-risk autism gene can alter architecture and organization of neurons, study finds

Biologists discover how a protein in our body works

Genetic variations affect and rewire phosphorylation signaling networks in SARS-CoV-2 infection

Simple change can maximize a single cell's production of extracellular vesicles

Tomosyn protein's key contribution to heterogeneity of neurons revealed

Study uncovers mechanism for insensitivity to key antimalarial drug in new pathogen variant

Researchers shed light on an important stage of early human embryogenesis for the first time

Study reveals a previously unknown mechanism for pancreatic cancer metastasis

Complex RNA structures could have untapped therapeutic potential in the fight against COVID-19

Genetic ancestry can explain population-level differences in immune response to the flu virus

Comprehensive genomic study maps the global resurgence of syphilis

Immune response to influenza virus influenced by genetic ancestry

Research reveals how disordered protein interaction orchestrates gene expression

LMU immunologists reveal how Roquin-1 controls the activity of immune cells

Method can help identify proteins in the body affected by chemicals

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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