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Iron-carrying extracellular vesicles promote viral-bacterial co-infection

The mechanism by which acute viral respiratory infections promote secondary bacterial growth and infection in the airways depends on iron-carrying extracellular sacs secreted by the cells lining the host's airways, report researchers from the University of Pittsburgh School of Medicine in a paper published today in Cell Reports.

26 Jan 2021

Two enzymes fuel transition from pre-cancer stem cells to leukemia stem cells

Since stem cells can continually self-regenerate, making more stem cells, and differentiate into many different specialized cell types, they play an important role in our development and health.

26 Jan 2021

Study shows why children of obese mothers have propensity to develop metabolic diseases

A Brazilian study published in the journal Molecular Human Reproduction helps understand why obese mothers tend to have children with a propensity to develop metabolic disease during their lifetime, as suggested by previous research.

26 Jan 2021

Remdesivir disrupts SARS-CoV-2 more effectively than other similar drugs

In the treatment of SARS-CoV-2, the virus that causes COVID-19, antiviral drug remdesivir has emerged as a promising candidate.

26 Jan 2021

Study uses computational framework to identify tamoxifen resistance markers in ER+ breast cancer

One common challenge of cancer therapy is when cancer cells don't respond to a drug that is usually able to kill or weaken them, known as treatment resistance.

26 Jan 2021

New NIH grant supports research on Alzheimer's disease caused by gene mutations

A new grant from the National Institute On Aging at the National Institutes of Health will support ongoing research at Rensselaer Polytechnic Institute to address Alzheimer's disease caused by gene mutations.

26 Jan 2021

Researchers find microbiome-controlled anti-inflammatory subsets of astrocytes

Astrocytes are the most abundant type of cells within the central nervous system (CNS), but they remain poorly characterized.

26 Jan 2021

G3BP proteins inhibit metabolic driver that plays a central role in cancers, neurological disorders

G3BP proteins inhibit the metabolic driver MTOR - a signaling protein that plays a central role in tumor diseases and developmental disorders of the brain. This is reported in this week´s issue of the renowned journal Cell.

26 Jan 2021

Scientists show how coconut oil is metabolized in the liver

Coconut oil has increasingly found its way into German kitchens in recent years, although its alleged health benefits are controversial. Scientists at the University of Bonn have now been able to show how it is metabolized in the liver.

26 Jan 2021

Microglial cells contribute to the negative mood experienced during neurological diseases

Special immune cells found in the brain, microglia, play a key role in the processes that make you feel uneasy and depressed in correlation with inflammation.

26 Jan 2021

Anchor proteins inhibit a key metabolic driver that plays critical role in cancer and neuronal diseases

Certain anchor proteins inhibit a key metabolic driver that plays an important role in cancer and developmental brain disorders.

26 Jan 2021

New study unravels complete sequence of DNA repair mechanism

Every living organism has DNA, and every living organism engages in DNA replication, the process by which DNA makes an exact copy of itself during cell division. While it's a tried-and-true process, problems can arise.

25 Jan 2021

World's first fully reversible manipulation of the circadian clock

The Nagoya University Institute of Transformative Bio-Molecules research team of Designated Associate Professor Tsuyoshi Hirota, Postdoctoral Fellow Simon Miller, Professor Kenichiro Itami and graduate student Tsuyoshi Oshima (Research Fellowship for Young Scientists, JSPS), in collaboration with the group of Professor Ben Feringa and Postdoctoral Fellow Dušan Kolarski of Groningen University in the Netherlands, have achieved a world first: fully reversible manipulation of the period of the circadian clock using light, by exchanging part of a compound with a light-activated switch.

25 Jan 2021

Stem cell based cell culture model to recapitulate important aspects of NAFLD

Nonalcoholic fatty liver disease (NAFLD) is a widespread condition in the Western World. Around 30% of the population have lipid droplets stored in their liver which diminish its function in the long term.

25 Jan 2021

New method can help identify potential anti-cancer drugs at a high pace

The enzymes in human cells known as histone deacetylases, or HDACs, are targets for a handful of anticancer drugs because of their ability to affect gene expression.

25 Jan 2021

UNSW develops a ceramic-based ink to 3D-print bone parts with living cells

3D printers may one day become a permanent fixture of the operating theatre after UNSW scientists showed they could print bone-like structures containing living cells.

25 Jan 2021

Study: Understanding nutrient accumulation within cycads is essential to effective horticultural management

Collective research to date regarding nutrients found in the leaves of contemporary cycad species has been inconsistent as far as data collection and narrow in scope, according to a University of Guam-led literature review published on Nov. 19 in Horticulturae journal.

24 Jan 2021

Corning to highlight newest products in 3D cell culture portfolio at SLAS2021

Corning Incorporated will highlight its latest technologies that support the advancement of 3D cell culture, automation, and drug discovery at this year's virtual Society for Laboratory Automation and Screening (SLAS) conference on Jan. 25 through 27.

22 Jan 2021

UC research team uses zebrafish to study a gene mutation that causes congenital scoliosis

Popular in aquariums all over the world, the zebrafish is native to South Asia. But here in a Cincinnati Children's laboratory, the freshwater variant plays a vital role in scientific discovery.

22 Jan 2021

Pancreatic β cell-derived exosomal miR-29s manipulate glucose homeostasis

In a new study published in Journal of Extracellular Vesicles, Chen-Yu Zhang's group at Nanjing University, School of Life Sciences, and Antonio Vidal-Puig's group at University of Cambridge report that pancreatic β cells secrete miR-29 family members (miR-29s) via exosomes in response to high levels of free fatty acids (FFAs).

22 Jan 2021

Life Science News

Iron-carrying extracellular vesicles promote viral-bacterial co-infection

Two enzymes fuel transition from pre-cancer stem cells to leukemia stem cells

Study shows why children of obese mothers have propensity to develop metabolic diseases

Remdesivir disrupts SARS-CoV-2 more effectively than other similar drugs

Study uses computational framework to identify tamoxifen resistance markers in ER+ breast cancer

New NIH grant supports research on Alzheimer's disease caused by gene mutations

Researchers find microbiome-controlled anti-inflammatory subsets of astrocytes

G3BP proteins inhibit metabolic driver that plays a central role in cancers, neurological disorders

Scientists show how coconut oil is metabolized in the liver

Microglial cells contribute to the negative mood experienced during neurological diseases

Anchor proteins inhibit a key metabolic driver that plays critical role in cancer and neuronal diseases

New study unravels complete sequence of DNA repair mechanism

World's first fully reversible manipulation of the circadian clock

Stem cell based cell culture model to recapitulate important aspects of NAFLD

New method can help identify potential anti-cancer drugs at a high pace

UNSW develops a ceramic-based ink to 3D-print bone parts with living cells

Study: Understanding nutrient accumulation within cycads is essential to effective horticultural management

Corning to highlight newest products in 3D cell culture portfolio at SLAS2021

UC research team uses zebrafish to study a gene mutation that causes congenital scoliosis

Pancreatic β cell-derived exosomal miR-29s manipulate glucose homeostasis

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest Life Science News