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Study shows ssRNA encapsidation results in stabilization of the Ebola virus nucleocapsid

The Ebola virus causes a serious infection with a mortality rate between 50% and 90%. Nucleoproteins in the virus assemble into a helical arrangement and encapsulate a single stranded RNA genome, ssRNA, to form a rodlike complex known as a nucleocapsid, which is critical to the function of the virus.

21 Oct 2020

Novel method can test the efficacy of antibacterial drugs on infectious microbes

A rapid and simple method for testing the efficacy of antibacterial drugs on infectious microbes has been developed and validated by a team of Penn State researchers.

21 Oct 2020

New study could help achieve multicolor imaging with fluorescent biosensors cells

With a little tweak of the color palette, University of Virginia School of Medicine researchers have made it easier for scientists to understand biological processes, track happenings inside individual cells, unravel the mysteries of disease and develop new treatments.

21 Oct 2020

Minuscule tracking devices show how living cells change with time

For the first time, scientists have introduced minuscule tracking devices directly into the interior of mammalian cells, giving an unprecedented peek into the processes that govern the beginning of development.

20 Oct 2020

Scientists show why zebra finches have problems with reproduction

In birds and other species alike, pairs can face considerable difficulties with reproduction. Scientists at the Max Planck Institute for Ornithology in Seewiesen have now shown in an extensive analysis of 23,000 zebra finch eggs that infertility is mainly due to males, while high embryo mortality is more a problem of the females.

20 Oct 2020

3D whole-heart imaging technique provides new insights on congenital heart disease

A cutting-edge technique that allows scientists to zoom into tiny details in a 3D image of a whole animal heart may lead to new insights on congenital heart disease.

20 Oct 2020

NMR Metabolomics as Novel Screening Tool for New-borns (For Research Only)

In this interview, Oscar Millet, group leader of the Precision Medicine and Metabolism group of the CIC bioGUNE, talked to News Medical about his research into the use of nuclear magnetic resonance spectroscopy (NMR) metabolomic analysis as a clinical screening tool. His team has used NMR to screen urine samples form new-borns for congenital metabolic disorders.

From Bruker BioSpin - NMR, EPR and Imaging 20 Oct 2020

Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain could guide design of antiviral agents

The outbreak of coronavirus disease (COVID-19) caused by SARS-CoV-2 virus continues to cause human infection and mortality worldwide. Currently, there are no specific viral protein-targeted therapeutics available.

20 Oct 2020

Researchers develop a molecular docking based webserver to predict drug targets

A highly effective drug therapy is urgently required to combat coronavirus disease 2019 (COVID-19). The authors of this article have developed a molecular docking based webserver, namely D3Targets-2019-nCoV, with two functions, one is for predicting drug targets for drugs or active compounds observed from clinic or in vitro/in vivo studies, the other is for identifying lead compounds against potential drug targets via docking.

20 Oct 2020

Study could offer important clues on factors affecting human microbiome rhythms

Nearly every organism hosts a collection of symbiotic microbes--a microbiome. It is now recognized that microbiomes are major drivers of health in all animals, including humans, and that these symbiotic systems often exhibit strong daily rhythms.

20 Oct 2020

Study shows air pollution drives demand for food delivery services

When the air outside is bad, office workers are more likely to order food delivery than go out for lunch, which in turn increases plastic waste from food packaging, according to a study by researchers from the National University of Singapore (NUS).

20 Oct 2020

Researchers map the first draft sequence of human proteome

Twenty years after the release of the human genome, the genetic "blueprint" of human life, an international research team, including the University of British Columbia's Chris Overall, has now mapped the first draft sequence of the human proteome.

20 Oct 2020

Study presents new framework to assess urban food waste policies and initiatives

Food waste is one of the most important issues of current food systems: Food and Agriculture Organization has estimated that more than one third of food is either lost or wasted along the entire food supply chain causing significant economic, social and environmental impacts.

20 Oct 2020

Researchers apply a novel technique to improve understanding of liver disease, immune activation

Human cells are encased by a membrane coated with diverse sugar molecules known as glycans. These glycans play many roles in health and disease, making them important to understand.

20 Oct 2020

Study: Localization of neurons is adapted to successful hunting sequence in zebrafish

Spotting, pursuing and catching prey - for many animals this is an essential task for survival. Scientists at the Max Planck Institute of Neurobiology now show in zebrafish that the localization of neurons in the midbrain is adapted to a successful hunting sequence.

20 Oct 2020

Scientists uncover important disease-fighting role for cells in the liver

Scientists at Scripps Research have uncovered an important disease-fighting role for cells called hepatocytes, which constitute most of the liver. The discovery could potentially be harnessed to develop new medicines for viral illnesses.

19 Oct 2020

Cell nucleus may play role in enabling cells to evade crowded environments

Like people, cells in the human body protect their personal space. They seem to know how much space they need, and if it gets too tight, most cells prefer to break free.

19 Oct 2020

New AI-based method of image analysis finds new cell types in tissue

In situ sequencing enables gene activity inside body tissues to be depicted in microscope images. To facilitate interpretation of the vast quantities of information generated, Uppsala University researchers have now developed an entirely new method of image analysis.

19 Oct 2020

Researchers discover gene that may help the body sense a full urinary bladder

In a National Institutes of Health (NIH)-funded study involving both mice and patients who are part of an NIH Clinical Center trial, researchers discovered that a gene, called PIEZO2, may be responsible for the powerful urge to urinate that we normally feel several times a day. The

19 Oct 2020

New method makes the superficial white matter visible in the living human brain

Traditionally, neuroscience regards the brain as being made up of two basic tissue types. Billions of neurons make up the grey matter, forming a thin layer on the brain's surface.

19 Oct 2020

Life Science News

Study shows ssRNA encapsidation results in stabilization of the Ebola virus nucleocapsid

Novel method can test the efficacy of antibacterial drugs on infectious microbes

New study could help achieve multicolor imaging with fluorescent biosensors cells

Minuscule tracking devices show how living cells change with time

Scientists show why zebra finches have problems with reproduction

3D whole-heart imaging technique provides new insights on congenital heart disease

NMR Metabolomics as Novel Screening Tool for New-borns (For Research Only)

Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain could guide design of antiviral agents

Researchers develop a molecular docking based webserver to predict drug targets

Study could offer important clues on factors affecting human microbiome rhythms

Study shows air pollution drives demand for food delivery services

Researchers map the first draft sequence of human proteome

Study presents new framework to assess urban food waste policies and initiatives

Researchers apply a novel technique to improve understanding of liver disease, immune activation

Study: Localization of neurons is adapted to successful hunting sequence in zebrafish

Scientists uncover important disease-fighting role for cells in the liver

Cell nucleus may play role in enabling cells to evade crowded environments

New AI-based method of image analysis finds new cell types in tissue

Researchers discover gene that may help the body sense a full urinary bladder

New method makes the superficial white matter visible in the living human brain

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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