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Advanced cryo-EM imaging reveals high-resolution structure of viral RNA replication complex

For the first time, scientists at the Morgridge Institute for Research have generated near atomic resolution images of a major viral protein complex responsible for replicating the RNA genome of a member of the positive-strand RNA viruses, the large class of viruses that includes coronaviruses and many other pathogens.

20 Jul 2020

Researchers visualize DNA G-quadruplex formation in live cells for the first time

The formation of four-stranded DNA has been tracked in living human cells, allowing scientists to see how it works, and its possible role in cancer.

20 Jul 2020

COVID-19 vaccine displays protective traits in nonhuman primates

A replicating RNA vaccine, formulated with a lipid-based nanoparticle emulsion that goes by the acronym LION, produces antibodies against the COVID-19 coronavirus in mice and primates with a single immunization. These antibodies potently neutralize the virus.

20 Jul 2020

Harvard scientists uncover the real reason behind goosebumps

If you've ever wondered why we get goosebumps, you're in good company -- so did Charles Darwin, who mused about them in his writings on evolution.

20 Jul 2020

Using AI to pinpoint neurons involved in gait reacquisition

Researchers at EPFL are able to get paralyzed rodents walking again by stimulating the animals' damaged spinal cords.

20 Jul 2020

Brains of all mammals exhibit equal connectivity, study finds

Researchers at Tel Aviv University, led by Prof. Yaniv Assaf of the School of Neurobiology, Biochemistry and Biophysics and the Sagol School of Neuroscience and Prof. Yossi Yovel of the School of Zoology, the Sagol School of Neuroscience, and the Steinhardt Museum of Natural History, conducted a first-of-its-kind study designed to investigate brain connectivity in 130 mammalian species.

20 Jul 2020

'Smart nanosheets' can help quickly isolate new types of proteins from mixtures

An interdisciplinary team from Frankfurt and Jena has developed a kind of bait with which to fish protein complexes out of mixtures.

20 Jul 2020

McGill researchers discover bacterial organelles involved in gene expression

Researchers at McGill University have discovered bacterial organelles involved in gene expression, suggesting that bacteria may not be as simple as once thought.

20 Jul 2020

Mutant zebrafish opens a window into evolutionary history of human spine

A chance mutation that led to spinal defects in a zebrafish has opened a little window into our own fishy past.

20 Jul 2020

How immune cells switch to attack mode

Unraveling a key motif: The T lymphocytes of the immune system work to destroy infected cells or cancer cells. To do so, they have to identify the threat: Molecules perceived as foreign - so-called antigens - bind to the T-cell receptor on the T cell surface.

20 Jul 2020

Study identifies toxicological risks of environmental pollutants in finless porpoises

A recent study just published in Environmental Science & Technology identified the toxicological risks of environmental pollutants to finless porpoises (Neophocaena asiaeorientalis).

20 Jul 2020

Study brings researchers one step closer to produce and blend medicines on a microscopic scale

For the first time, a single, twisted nanoparticle has been accurately measured and characterised in a lab, taking scientists one vital step closer to a time when medicines will be produced and blended on a microscopic scale.

20 Jul 2020

Olympus scanR high-content screening station v. 3.2 brings improved image quality with award-winning X Line objectives

The scanR high-content screening (HCS) station version 3.2 delivers improved image quality, better quantitative data, support for challenging segmentation and classification applications and increased speed to help life science researchers maximize the information they get from their samples.

From Evident Corporation - Life Sciences 20 Jul 2020

Researchers determine how SARS-CoV-2 inhibits protein synthesis

Researchers from Munich and Ulm have determined how the pandemic coronavirus SARS-CoV-2 inhibits the synthesis of proteins in infected cells and shown that it effectively disarms the body's innate immune system.

19 Jul 2020

UNH scientists identify quicker and less expensive way to count sperm in lobsters

Researchers at the University of New Hampshire have identified a quicker and less expensive way to count sperm in lobsters that could help scientists looking at any animal better understand mating, a key aspect of species survival.

19 Jul 2020

Study reveals intricate details about the biology of huntingtin protein

A new study reveals intricate details about the biology of the huntingtin protein (HTT), which is responsible for Huntington's disease.

17 Jul 2020

Groundbreaking technology could enhance therapeutic efficiency of nanomedicines

Researchers from the Moscow Institute of Physics and Technology and their colleagues from Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry and Prokhorov General Physics Institute of the Russian Academy of Sciences have developed a breakthrough technology to resolve a key problem that has prevented the introduction of novel drugs into clinical practice for decades.

17 Jul 2020

Study shows a promising, new approach to treating Alzheimer's disease

With over 1.2 million people affected in Germany alone and over 50 million people worldwide, Alzheimer's disease, also referred to simply as Alzheimer's, is one of the greatest medical and social challenges of our time.

17 Jul 2020

Novel nanospectroscopy measures biomolecular changes induced by drugs in human cells

Synchrotron InfraRed Nanospectroscopy has been used for the first time to measure biomolecular changes induced by a drug (amiodarone) within human cells (macrophages) and localized at 100 nanometre scale, i.e. two orders of magnitude smaller than the IR wavelength used as probe.

17 Jul 2020

Avicenna.AI secures FDA clearance for its CINA Head neurovascular imaging artificial intelligence tool

Medical imaging AI specialist Avicenna.AI today announced it has received 510(k) clearance from the US Food and Drug Administration for its CINA Head triage AI solution for neurovascular emergencies.

17 Jul 2020

Life Science News

Advanced cryo-EM imaging reveals high-resolution structure of viral RNA replication complex

Researchers visualize DNA G-quadruplex formation in live cells for the first time

COVID-19 vaccine displays protective traits in nonhuman primates

Harvard scientists uncover the real reason behind goosebumps

Using AI to pinpoint neurons involved in gait reacquisition

Brains of all mammals exhibit equal connectivity, study finds

'Smart nanosheets' can help quickly isolate new types of proteins from mixtures

McGill researchers discover bacterial organelles involved in gene expression

Mutant zebrafish opens a window into evolutionary history of human spine

How immune cells switch to attack mode

Study identifies toxicological risks of environmental pollutants in finless porpoises

Study brings researchers one step closer to produce and blend medicines on a microscopic scale

Olympus scanR high-content screening station v. 3.2 brings improved image quality with award-winning X Line objectives

Researchers determine how SARS-CoV-2 inhibits protein synthesis

UNH scientists identify quicker and less expensive way to count sperm in lobsters

Study reveals intricate details about the biology of huntingtin protein

Groundbreaking technology could enhance therapeutic efficiency of nanomedicines

Study shows a promising, new approach to treating Alzheimer's disease

Novel nanospectroscopy measures biomolecular changes induced by drugs in human cells

Avicenna.AI secures FDA clearance for its CINA Head neurovascular imaging artificial intelligence tool

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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