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Study reveals molecular causes of brain asymmetry

Scientists may have solved one of the most puzzling and persistent mysteries in neuroscience: why some people are "right-brained" while others are "left-brained."

15 Apr 2020

New study offers insight on how bacteria exchange drug resistance genes

Researchers have been able to identify and track the exchange of genes among bacteria that allow them to become resistant to drugs, according to a new study published today in eLife.

14 Apr 2020

Technologies converge on interacting surfaces in protein complexes

Researchers have fine-tuned a method to pinpoint surfaces within interacting large multi-protein complexes.

14 Apr 2020

Predicting the evolution of genetic mutations

Biologists have developed an algorithm able to predict how genetic mutations can make critical proteins change with evolution.

14 Apr 2020

UTSW researchers show how vulnerable cells armor themselves against infection

Cells in some of the body's most vulnerable entry routes to bacterial infection buffer themselves when the immune system detects danger by reorganizing the cholesterol on their surfaces, a new study led by UTSW scientists suggests.

13 Apr 2020

Skoltech scientists propose new method to make doping tests quicker

Skoltech scientists and their colleagues proposed a way to simplify the search for traces of medicines, narcotic substances and sports doping drugs in human biological samples by performing two additional tests with the search domain reduced tenfold.

13 Apr 2020

Toxic cell atlas can guide discovery of new drugs for neurodegeneration

A common thread in many inflammatory and neurodegenerative diseases, including multiple sclerosis (MS), is damage caused by oxidative stress. Oxidative stress occurs when cells produce toxic substances known as reactive oxygen species, which are damaging nerve cells and other cells in the body.

13 Apr 2020

Super-charging production of drugs for COVID-19

Researchers are ramping up production of a promising drug that has proven effective in obliterating SARS-CoV in cellular cultures. The team hopes that the drug might also be effective in the fight against SARS's close genetic cousin, the novel coronavirus (COVID-19).

13 Apr 2020

UB biologist investigates how foxglove plants create medicinal compounds

Foxglove plants, found in many gardens, are known for the showers of bell-shaped flowers they produce.

13 Apr 2020

New insights into the building blocks of periodontitis

Porphyromonas gingivalis is a major bacterial pathogen which leads to periodontitis also known as gum disease. In Japan, 80% of adults aged 35 and over suffer from this disease. What's more, P. gingivalis has also been linked to rheumatoid arthritis, cardiovascular disease, pancreatic cancer, and even Alzheimer's disease.

13 Apr 2020

Chinese scientists report high-resolution crystal structure of COVID-19 main protease

A team of Chinese scientists has reported the high-resolution crystal structure of the main protease (Mpro) of the COVID-19 virus and has identified drugs that may hold promise in combating the virus.

13 Apr 2020

Molecular pathway responsible for TNBC's progression and spread identified

Immunotherapies have revolutionized treatment for people with a variety of cancers. But when given to those with triple-negative breast cancer, a particularly aggressive form of the disease, less than 20% respond.

13 Apr 2020

New technique for imaging proteins in 3D

A team of scientists including researchers at the National Synchrotron Light Source II (NSLS-II)--a U.S. Department of Energy Office of Science User Facility at DOE's Brookhaven National Laboratory--have demonstrated a new technique for imaging proteins in 3-D with nanoscale resolution.

13 Apr 2020

Large-scale proteomic analysis links glucose metabolism proteins and AD biology

In the largest study to date of proteins related to Alzheimer's disease, a team of researchers has identified disease-specific proteins and biological processes that could be developed into both new treatment targets and fluid biomarkers.

13 Apr 2020

Chemists identify a drug to rescue winter depression-like behavior

A group of animal biologists and chemists at the Institute of Transformative Bio-Molecules, Nagoya University, has used a chemical genomics approach to explore the underlying mechanism of winter depression-like behavior and identified a drug that rescues winter depression-like behavior in medaka fish.

13 Apr 2020

Study finds dependency of a type of small RNA on personal attributes

The cells in our body are home to thousands of tiny molecules called RNAs. There are many different types of RNAs – some carry the code for specific proteins to be made, some transport things within the cell, and some can influence which genes get turned on or off.

13 Apr 2020

Effective porous plastic filters for respiratory devices

Porvair Sciences reports on increased demand for the 3D moulded intake filters and vent diffusers it supplies to GCE Healthcare - manufacturer of the Zen-O lite™ Portable Oxygen Concentrator.

From Porvair Sciences Limited 13 Apr 2020

Inhibition of sphingolipid metabolism and neurodegenerative diseases

Disrupting production of sphingolipids in neurons improved neurodegeneration symptoms and increased survival in a mouse model.

13 Apr 2020

Unraveling interactions between metal ions and peptides may lead to new therapies for diseases

Copper ions could play a key role when peptide folding goes wrong and leads to harmful aggregates.

12 Apr 2020

Stuttering DNA controls development of mosquito embryos

All organisms have DNA, the genetic material that provides a blueprint for life. The long double-helix-shaped DNA molecules in the body's cells are first translated into RNA molecules and then translated into proteins that ensure the functioning of the cell and the entire organism.

12 Apr 2020