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Researchers discover genomic characteristics that define testicular germ cell cancer

Testicular germ cell cancer, a disease that is rare but growing in incidence in men in the United States, is considered to be among the most curable of solid tumors. Now researchers from the University of North Carolina Lineberger Comprehensive Cancer Center and a consortium of institutions have discovered the genetic and genomic characteristics that define the disease.

12 Jun 2018

AbCellera and Denali collaborate to discover new antibodies to fight neurodegenerative diseases

AbCellera Biologics Inc. today announced the successful completion of the first phase of its collaboration with Denali Therapeutics Inc.

12 Jun 2018

Scientists discover first genetic marker for bone tumor

The first genetic marker for the bone tumor, osteoblastoma, has been discovered by scientists at the Wellcome Sanger Institute and their collaborators.

12 Jun 2018

Combination of antibodies shown to cause rheumatoid arthritis

Researchers have shown that severe inflammation and joint damage in rheumatoid arthritis (RA) is primarily caused by a combination of different antibodies.

12 Jun 2018

TU Graz researchers manipulate enzymes to build ring-shaped molecular structures

TU Graz researchers managed for the first time ever to 'retrain' an enzyme to build ring-shaped molecular structures instead of performing its natural task of reducing double bonds.

12 Jun 2018

IU researchers observe bacteria's 'DNA uptake' process

Indiana University scientists have made the first direct observation of a key step in the process that bacteria use to rapidly evolve new traits, including antibiotic resistance.

12 Jun 2018

Customising T-cells for cancer immunotherapy

T-cell immunotherapy is revolutionizing cancer treatments. CD8+ T cells are modified to recognize tumor-specific antigens and induce an immune response.

12 Jun 2018

Synthetic gene reveals potential therapeutic target for rare, inherited disease

DNA Repair is essential for a healthy organism. In every day of our lives, tens of thousands of damages occur in the genetic material of our cells. Hence, it is not surprising that a broad variety of repair mechanisms developed in the course of evolution that enables cells to quickly react and patch up the affected DNA strands.

11 Jun 2018

New DNA test identifies men at highest risk of prostate cancer

A major new study of more than 140,000 men has identified 63 new genetic variations in the DNA code that increase the risk of prostate cancer.

11 Jun 2018

CRISPR-Cas9 technique may raise cancer risk

Therapeutic use of gene editing with the so-called CRISPR-Cas9 technique may inadvertently increase the risk of cancer, according to a new study from Karolinska Institutet, Sweden, and the University of Helsinki, Finland, published in Nature Medicine.

11 Jun 2018

Translate Bio collaborates with Sanofi to develop mRNA vaccines for infectious diseases

Translate Bio, a clinical-stage messenger RNA therapeutics company developing a new class of potentially transformative medicines to treat diseases caused by protein or gene dysfunction, announced today a multi-year research and development collaboration and exclusive licensing agreement with Sanofi Pasteur, the vaccines global business unit of Sanofi, to develop mRNA vaccines for up to five undisclosed infectious disease pathogens.

11 Jun 2018

Genetic mutation shown to cause bipolar disorder

Researchers have discovered a mutation that may increase the risk of bipolar disorder through a complex interplay between serotonin and mitochondrial signaling.

11 Jun 2018

Researchers identify new form of depression

In a new study, researchers from Hiroshima University have identified a new form of depression that could be used to inform a new generation of treatments.

11 Jun 2018

Research drug may one day be novel treatment for systemic inflammatory response syndrome

When trauma spills the contents of our cell powerhouses, it can evoke a potentially deadly immune response much like a severe bacterial infection.

11 Jun 2018

Researchers identify enzyme that controls cell’s collagen secretion

Researchers at Tokyo Institute of Technology have identified an enzyme that controls how much our cells secrete collagen.

11 Jun 2018

Study: Small RNA chains could regulate the genes involved in salmonella's virulence

A series of small RNA fragments are the regulator factors involved in a new control mechanism for salmonella virulence, a pathogenic bacterium which causes bacterial gastroenteritis with a high incidence -more than 100,000 cases per year- in Europe

8 Jun 2018

Researchers identify oldest bubonic plague genome

An international team of researchers led by the Max Planck Institute for the Science of Human History has analyzed two 3,800-year-old Y. pestis genomes that suggest a Bronze Age origin for bubonic plague.

8 Jun 2018

Using Nanomechanical Testing to Understand the Mechanical Efficiency of Biomaterials

Biological materials exhibit superior mechanical properties relative to their weight when compared to the majority of all man-made materials. In addition to this, organisms can construct these materials using a very limited palette.

From Bruker Nano Surfaces and Metrology 8 Jun 2018

International research team develops simplified CRISPR

Details of an advanced form of CRISPR technology have been published in Nature Communications.

8 Jun 2018

Scientists find role of schizophrenia gene in brain development

A USC research team identified 150 proteins affecting cell activity and brain development that contribute to mental disorders, including schizophrenia, bipolar condition and depression.

8 Jun 2018

Life Science News

Researchers discover genomic characteristics that define testicular germ cell cancer

AbCellera and Denali collaborate to discover new antibodies to fight neurodegenerative diseases

Scientists discover first genetic marker for bone tumor

Combination of antibodies shown to cause rheumatoid arthritis

TU Graz researchers manipulate enzymes to build ring-shaped molecular structures

IU researchers observe bacteria's 'DNA uptake' process

Customising T-cells for cancer immunotherapy

Synthetic gene reveals potential therapeutic target for rare, inherited disease

New DNA test identifies men at highest risk of prostate cancer

CRISPR-Cas9 technique may raise cancer risk

Translate Bio collaborates with Sanofi to develop mRNA vaccines for infectious diseases

Genetic mutation shown to cause bipolar disorder

Researchers identify new form of depression

Research drug may one day be novel treatment for systemic inflammatory response syndrome

Researchers identify enzyme that controls cell’s collagen secretion

Study: Small RNA chains could regulate the genes involved in salmonella's virulence

Researchers identify oldest bubonic plague genome

Using Nanomechanical Testing to Understand the Mechanical Efficiency of Biomaterials

International research team develops simplified CRISPR

Scientists find role of schizophrenia gene in brain development

Extending the reach of Amperia™

Modular cleanrooms: Enhancing flexibility and compliance

Redefining control and consistency in anaerobic microbiome workflows

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