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IDSA guidelines describe best methods for diagnosis of prosthetic joint infections

Of the one million people each year who get hips and knees replaced, as many as 20,000 will get an infection in the new joint, a number that is expected to skyrocket in the next 20 years. Multispecialty physician teams need to work together to reduce disability, death and costs associated with the ever-growing number of these prosthetic joint infections, note the first guidelines on the topic being released by the Infectious Diseases Society of America (IDSA).

9 Dec 2012

More than 100 academic institutions to participate in Mathematics of Planet Earth 2013

More than 100 academic institutions and scholarly societies have joined in a major world-wide initiative: Mathematics of Planet Earth (MPE) 2013. This year-long effort will highlight the contributions made by mathematics in tackling global problems, including natural disasters such as hurricanes, earthquakes, and tsunamis; climate change; sustainability; and pandemics.

9 Dec 2012

C5aRA treatment could be effective against periodontitis

Periodontitis, a form of chronic gum disease that affects nearly half of the U.S. adult population, results when the bacterial community in the mouth becomes unbalanced, leading to inflammation and eventually bone loss. In its most severe form, which affects 8.5 percent of U.S. adults, periodontitis can impact systemic health.

9 Dec 2012

Celldex announces final results from CDX-011 Phase 2b study on GPNMB-expressing breast cancer

Celldex Therapeutics, Inc. today announced final results from the Company's randomized Phase 2b EMERGE study of CDX-011 in patients with glycoprotein NMB (GPNMB)-expressing, advanced, heavily pretreated breast cancer.

9 Dec 2012

GOP Sen. Corker says party should accept tax hikes to get spending cuts

As pressure builds for a "fiscal cliff" deal, several key players talked about strategy on the Sunday morning news shows. Meanwhile, Politico reports that Republicans' hope of a big victory on cutting entitlement spending has dimmed while The Hill looks at Democrats' new willingness to consider means testing for Medicare.

9 Dec 2012

Anti-seizure drug benefits women with severe morning sickness

Good news may be on the horizon for Kate Middleton, Duchess of Cambridge, and other women stricken with severe nausea and vomiting during pregnancy, thanks to the work of a University at Buffalo professor who is conducting research on a drug that is showing success treating pregnant women with this condition.

8 Dec 2012

U.S. government's draft guidance on funding for H5N1 research receives 'mixed reception,' Science reports

"Researchers are giving a mixed reception to a draft U.S. government plan to do more stringent funding reviews of certain kinds of H5N1 avian influenza research -- and perhaps even require some studies to be kept secret," Science reports.

8 Dec 2012

Lancet examines Indonesia's efforts to reduce maternal mortality

The Lancet examines Indonesia's efforts to reduce maternal mortality, one of the Millennium Development Goals President Susilo Bambang Yudhoyono has identified as a national priority.

8 Dec 2012

IQWiG investigates benefits of rilpivirine for HIV treatment

Since the start of 2012, a new drug called rilpivirine has been available for adult patients infected with the human immunodeficiency virus type 1 (HIV-1). It is marketed by two different pharmaceutical companies, by one as a single agent (trade name Edurant-) and by the other as a fixed combination with other HIV drugs (trade name Eviplera-).

8 Dec 2012

New public-private partnership will allow Brazil to produce patented ARV for national treatment program

For the first time, Brazil in 2013 will enter into a new type of public-private partnership that allows the nation to produce a generic version of the antiretroviral (ARV) drug atazanavir sulphate, which will be under patent through its producer Bristol-Myers Squibb until 2017, Inter Press Service reports.

8 Dec 2012

International community should 'not forget' importance of treatment, care for children with HIV

The "progress and momentum" behind stopping mother-to-child HIV transmission is "reason to celebrate," Charles Lyons, president and CEO of the Elizabeth Glaser Pediatric AIDS Foundation, and Peter Twyman, CEO of Keep a Child Alive, write in The Hill's "Congress Blog."

8 Dec 2012

Lancet editorial examines possibility of 'AIDS-free generation,' PEPFAR blueprint

"After three decades of global emergency responses and a series of scientific breakthroughs in the fight against HIV/AIDS, it is now tempting to ask if we are marching towards the end of AIDS," an editorial in the Lancet states.

8 Dec 2012

Treadmill test can accurately predict coronary artery disease in women over 65

Although there is a widespread belief among physicians that the exercise treadmill test (ETT) is not reliable in evaluating the heart health of women, UC Davis researchers have found that the test can accurately predict coronary artery disease in women over the age of 65. They also found that two specific electrocardiogram (EKG) indicators of heart stress during an ETT further enhanced its predictive power.

8 Dec 2012

Nokia to donate infant delivery kits to UNFPA

UNFPA and mobile phone company Nokia announced this week that the "company will donate the equivalent of 3,000 clean delivery kits to the fund," according to an UNFPA press release.

8 Dec 2012

WHO's decision to 'monitor' R&D 'deeply disappointing'

In this PLoS "Speaking of Medicine" blog post, Julien Potet and Katy Athersuch of Medecins Sans Frontieres' (MSF) Access Campaign say that the WHO's decision last week to "simply continue monitoring" the medical research and development (R&D) industry's ability to address the needs of people living in developing countries "by creating a global R&D 'observatory'" is "a deeply disappointing outcome that will not help re-shape priorities, increase funding or catalyze development of urgently needed new medical tools; at best it will only underscore further how badly these actions are needed."

8 Dec 2012

GlobalPost blog interviews reporter Joanne Silberner about PRI series on cancer in developing world

GlobalPost's "Global Pulse" blog features an interview with freelance reporter and artist-in-residence at the University of Washington in Seattle Joanne Silberner, a former NPR correspondent, about her recent series for PRI's "The World," titled "Cancer's New Battleground -- The Developing World."

8 Dec 2012

FAO report calls for increased investments in global agriculture to eradicate hunger

"Excessive corruption, poor infrastructure and scarce government resources were deterring investment in agriculture and contributing to high levels of malnourishment around the world," Xinhua writes, noting the release on Thursday of the U.N. Food and Agriculture Organization's (FAO) annual report.

8 Dec 2012

Cost-benefit analysis of TasP compared with circumcision, ART

In a study published online in the Proceedings of the National Academy of Sciences, Till Barnighausen, David Bloom, and Salal Humair of the Harvard School of Public Health examine "whether [HIV treatment as prevention (TasP)] is indeed a game changer or if comparable benefits are obtainable at similar or lower cost by increasing coverage of medical male circumcision (MMC) and antiretroviral treatment (ART)."

8 Dec 2012

Baby boomers with liver cancer drive demand for liver transplantation

New research reveals that the greatest demand for liver transplantation due to hepatitis C (HCV)-related liver disease occurs among Americans born between 1941 and 1960. Findings in the December issue of Liver Transplantation, a journal published by Wiley on behalf of the American Association for the Study of Liver Diseases (AASLD), suggest that continuing increased demand for transplantation is driven by the development of liver cancer in baby boomers with HCV, but that the demand may decrease as patients born in this time period continue to grow older.

7 Dec 2012

States cut anti-tobacco efforts despite record revenue from taxes, national settlement

States spend less than 2 percent of what they collect from tobacco taxes and a national tobacco settlement on smoking cessation and prevention efforts, a new report says.

7 Dec 2012

Medical News

IDSA guidelines describe best methods for diagnosis of prosthetic joint infections

More than 100 academic institutions to participate in Mathematics of Planet Earth 2013

C5aRA treatment could be effective against periodontitis

Celldex announces final results from CDX-011 Phase 2b study on GPNMB-expressing breast cancer

GOP Sen. Corker says party should accept tax hikes to get spending cuts

Anti-seizure drug benefits women with severe morning sickness

U.S. government's draft guidance on funding for H5N1 research receives 'mixed reception,' Science reports

Lancet examines Indonesia's efforts to reduce maternal mortality

IQWiG investigates benefits of rilpivirine for HIV treatment

New public-private partnership will allow Brazil to produce patented ARV for national treatment program

International community should 'not forget' importance of treatment, care for children with HIV

Lancet editorial examines possibility of 'AIDS-free generation,' PEPFAR blueprint

Treadmill test can accurately predict coronary artery disease in women over 65

Nokia to donate infant delivery kits to UNFPA

WHO's decision to 'monitor' R&D 'deeply disappointing'

GlobalPost blog interviews reporter Joanne Silberner about PRI series on cancer in developing world

FAO report calls for increased investments in global agriculture to eradicate hunger

Cost-benefit analysis of TasP compared with circumcision, ART

Baby boomers with liver cancer drive demand for liver transplantation

States cut anti-tobacco efforts despite record revenue from taxes, national settlement

Voltammetry and machine learning for real-time neurotransmitter detection

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

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