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Surgical features determine survival in radical prostatectomy patients

The impact of adjuvant radiotherapy on cancer-specific mortality and overall mortality rates in patients who have undergone radical prostatectomy depends on the cumulative number of certain pathologic features found during surgery, report researchers.

5 Nov 2012

Cervical cancer risk remains high after CIN treatment

Women who undergo treatment for screening-detected cervical intraepithelial neoplasia are more than four times more likely to develop cervical cancer than women with normal smear tests, research suggests.

5 Nov 2012

Round-the-clock ICU intensivists could reduce mortality rates, length of stay

Implementing 24-hour intensivists at medical intensive care units could reduce patient mortality rates, and significantly reduce patients' length of stay, indicate study results.

5 Nov 2012

Sapacitabine tolerated, efficacious in elderly leukemia patients

The nucleoside analog sapacitabine appears to be “active and tolerable” in elderly patients with acute myeloid leukemia, say authors of a phase II study reported in the Lancet Oncology.

5 Nov 2012

Smoke-free laws lead to fewer heart attacks

A recent decline in the incidence of myocardial infarction in Olmsted County, Minnesota, USA, could be due to the implementation of smoke-free laws, researchers suggest.

5 Nov 2012

Traditional CV risk factors linked to peripheral artery disease

Smoking, Type 2 diabetes, hypertension, and hypercholesterolemia are significantly associated with the risk for clinically significant peripheral artery disease in men, with each additional factor doubling the risk, conclude US and Dutch researchers.

5 Nov 2012

Genetic polymorphisms linked with community-acquired pneumonia

Seven genetic polymorphisms have been shown to be associated with community-acquired pneumonia, research shows.

5 Nov 2012

Imaging-based therapy benefits ‘wake-up stroke’ patients

Undertaking thrombolysis on the basis of magnetic resonance imaging findings in patients with stroke of unknown onset time may double their chances for a good outcome, say researchers.

5 Nov 2012

Suicide rates in the US have increased sharply since the economic crisis began

Suicide rates in the US have risen sharply since the economic crisis took hold in 2007, warn the authors of Correspondence published Online First in The Lancet.

5 Nov 2012

AcelRx commences dosing in ARX-04 sufentanil NanoTab Phase 2 study for acute and breakthrough pain

AcelRx Pharmaceuticals, Inc., a specialty pharmaceutical company focused on the development and commercialization of innovative therapies for the treatment of acute and breakthrough pain, today announced that it has dosed the first subjects in a Phase 2, placebo-controlled, dose-finding study of its ARX-04 sufentanil NanoTab product candidate.

5 Nov 2012

Humana to acquire Metropolitan Health Networks

Humana Inc. and Metropolitan Health Networks, Inc. today announced that they have entered into a definitive agreement pursuant to which Humana will acquire Metropolitan in a transaction valued at approximately $850 million plus transaction costs.

5 Nov 2012

Self-harm among young people should not be over-interpreted

Self-harm is common among young people. Many have at one time scratched, punctured or cut themselves or hit their head forcefully against a wall, and the behaviour is almost as common among boys as girls. However, it may not be appropriate to compare young people who self-harm and adult psychiatric patients who self-harm. Knowledge is needed in order not to over-interpret the behaviour of the young people, according to psychologist Jonas Bjärehed, who has recently presented his thesis at Lund University in Sweden.

5 Nov 2012

Larger aneurysms linked to greater fluctuations in flow behaviour

Brain aneurysms occur in about six percent of the population. They are dilated sections of blood vessels, which can deteriorate over time until the blood vessel wall ruptures, resulting in a haemorrhage. This causes a loss of mental functions and severe headaches. Haemorrhages of this kind can even be life threatening. The treatment of such patients involves complex medical decision-making. The models developed by Julia Mikhal can be of great use in this regard.

5 Nov 2012

First Edition: November 5, 2012

Today's headlines include reports about the final round of polls, forecasts regarding which party will control the House and Senate and analysis of how campaign-trail messages have been playing during the election season's final hours.

5 Nov 2012

PsiOxus receives UK government grant to initiate ColoAd1 Phase I/II trial for ovarian cancer

PsiOxus Therapeutics, Ltd., a development stage biotechnology company, today announced the award of a £1.7 million ($2.7 million) grant from the UK government-backed Biomedical Catalyst to initiate a Phase I/II clinical trial to assess the use of ColoAd1 in the treatment of platinum-resistant, recurrent ovarian cancer.

5 Nov 2012

Study compares effectiveness of CABG surgery with PCI for adults with diabetes and heart disease

Adults with diabetes and multi-vessel coronary heart disease who underwent cardiac bypass surgery had better overall heart-related outcomes than those who underwent an artery-opening procedure to improve blood flow to the heart muscle, according to the results from an international study. The research was supported by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health.

5 Nov 2012

Family members less likely to administer CPR for cardiac arrests: Japanese study

Family members didn't give CPR for cardiac arrests as often as passers-by or friends in a Japanese study presented at the American Heart Association's Scientific Sessions 2012.

5 Nov 2012

SpinChip aims to help doctors analyse patients' blood samples on the spot

The Norwegian company SpinChip aims to help doctors analyse patients' blood samples on the spot and provide immediate results.

5 Nov 2012

Study highlights potential treatment that reduces kidney growth

Autosomal-dominant polycystic kidney disease (ADPKD) is one of the most common genetic disorders, affecting one in every 1,000 people and responsible for up to ten percent of patients on dialysis worldwide. The disease is characterized by the development of cysts that lead to progressive kidney failure and necessitate dialysis or a kidney transplant in most patients aged around fifty. Moreover, the persistent cyst growth causes high blood pressure and painful complications.

5 Nov 2012

Vitamin D deficiency: an interview with Kellie Bilinski

We know that vitamin D is important in keeping bones strong. In the last 30-40 years it has also been realized that vitamin D has a lot of other roles in the body. Vitamin D essentially has a role in any cell in the body that has a vitamin D receptor.

5 Nov 2012