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Club foot ankle osteoarthritis risk revealed

Patients treated for clubfoot have a low long-term risk for ankle osteoarthritis, say Swedish researchers after studying patients aged over 60 years.

1 Nov 2012

Cardio exercise OK in high-risk CVD patients

US study results indicate that cardiopulmonary exercise is well tolerated, even when performed by individuals with high-risk cardiovascular disease.

1 Nov 2012

Better access to fresh, local food urged for underprivileged families

Initiatives that improve the ability of socially disadvantaged families to obtain local produce are sorely needed, say US researchers.

1 Nov 2012

Partial dentin removal superior to stepwise excavation over long term

Partial caries removal treatment for individuals with deep caries lesions results in significantly improved pulp vitality after 3 years than does stepwise excavation, indicate Brazilian study findings.

1 Nov 2012

Aerobic exercise may offer new treatment option for ADHD

Research suggests that moderate aerobic exercise may offer a new treatment option for children with attention deficit/hyperactivity disorder.

1 Nov 2012

Implant-based breast reconstruction has disadvantages

Implant-based breast reconstruction, particularly immediate reconstruction, is associated with a higher failure rate than a free flap technique in obese people, suggest researchers.

1 Nov 2012

FoXTROT results: preoperative chemo could become new standard

Preoperative chemotherapy is a feasible option for resectable advanced colon cancer, show results of the FoXTROT trial.

1 Nov 2012

Bone quality reduced in mood disorder patients

Results from an Australian study show that men and young women with mood disorders have significantly lower bone quality than their mentally healthy counterparts.

1 Nov 2012

Psychotic symptoms increase suicidality risk in adolescents

The presence of psychotic symptoms is associated with a significantly increased risk for suicidal behavior in adolescents, research shows.

1 Nov 2012

Primary care improvement program shows benefits of collaboration

A collaborative primary care program aimed at enhancing provision for chronic diseases, patient self-management, access, and Aboriginal healthcare has shown improvement across the vast majority of measures, Australian study findings indicate.

1 Nov 2012

Genetic underpinning of placebo effect identified

US researchers have identified a gene that appears to be responsible for the placebo effect.

1 Nov 2012

Acupuncture shows promise in head and neck patients with xerostomia

Acupuncture significantly relieves the symptoms of xerostomia, or dry mouth, compared with oral care education in patients who have undergone radical or adjuvant radiotherapy for head and neck cancer, indicate the results of a randomized crossover trial.

1 Nov 2012

Social disadvantage may increase risk for psychosis

Results from a UK study suggest that social disadvantage is associated with an increased risk for developing psychosis.

1 Nov 2012

Treatment rate high at end of life for prostate cancer patients

Approximately one-third of men with castration-resistant prostate cancer receive some form of treatment in the last 3 months of life, show US study results.

1 Nov 2012

Multiple sclerosis disease activity reduced by leukaemia drug, even when first-line treatment has failed

A drug which was originally developed to treat leukaemia and other cancers of the immune system offers substantial improvements over existing treatments in reducing relapse rates for people with multiple sclerosis (MS), even when they have not responded well to first-line treatment, according to the results of two phase 3 trials published Online First in The Lancet.

1 Nov 2012

Teva third quarter 2012 net revenues increase 14% to $5.0 billion

Teva Pharmaceutical Industries Ltd. today reported results for the quarter ended September 30, 2012.

1 Nov 2012

Omeros initiates enrollment in OMS824 Phase 1 trial for schizophrenia and Huntington's

Omeros Corporation today announced that the first subject has been enrolled in the Company's Phase 1 clinical trial evaluating OMS824, the lead compound in Omeros' phosphodiesterase 10 (PDE10) program.

1 Nov 2012

Study finds link between severe sepsis and chronic diseases

It's a major cause of death, yet few of us have ever heard of it. Sepsis occurs when a patient's immune system overreacts to an infection, triggering a potentially fatal, system-wide inflammation. Severe sepsis strikes about 750,000 Americans each year, most of them older and often ill, with as many as half of these patients dying as septic shock shuts down their organs. Furthermore, patients in many Southern states are about twice as likely to develop sepsis for reasons unknown.

1 Nov 2012

Blocking hyaluronidase activity can help repair brain damage associated with MS

Researchers at Oregon Health & Science University have discovered that blocking a certain enzyme in the brain can help repair the brain damage associated with multiple sclerosis and a range of other neurological disorders.

1 Nov 2012

Dysfunction in SRGAP3 protein causes developmental brain disorders

A new research discovery has the potential to revolutionize the biological understanding of some childhood psychiatric disorders. Specifically, scientists have found that when a single protein involved in brain development, called "SRGAP3," is malformed, it causes problems in the brain functioning of mice that cause symptoms that are similar to some mental health and neurological disorders in children.

1 Nov 2012