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Social or daily drinking may be more harmful to brain health

Drinking a couple of glasses of wine each day has generally been considered a good way to promote cardiovascular and brain health. But a new Rutgers University study indicates that there is a fine line between moderate and binge drinking - a risky behavior that can decrease the making of adult brain cells by as much as 40 percent.

25 Oct 2012

Survey identifies factors that could affect future workforce supply of anesthesiologists

A large, first-of-its-kind national survey of older anesthesiologists has gathered important data that could be used by physicians and their employers to prepare for an expected undersupply of anesthesiologists in the near future.

25 Oct 2012

FDA accepts ARIAD’s ponatinib NDA for filing

ARIAD Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) has accepted for filing the New Drug Application (NDA) for accelerated review of ARIAD's investigational BCR-ABL inhibitor, ponatinib, in patients with resistant or intolerant chronic myeloid leukemia (CML) or Philadelphia-chromosome positive acute lymphoblastic leukemia (Ph+ ALL).

25 Oct 2012

Hot flashes and night sweats can return after SSRI treatment in women

Hot flashes and night sweats can return after women stop using escitalopram-an antidepressant-to treat these menopause symptoms, according to a study published online this month in Menopause, the journal of the North American Menopause Society.

25 Oct 2012

Roundup: States raise employee insurance contributions to save money; Minn. seeking $80M more for exchange; Selling insurance in malls

Financially strapped state and local governments are saving billions of dollars on health insurance by cutting back on free coverage for employees and raising worker contributions, a USA Today analysis finds. Government workers still enjoy more generous health benefits than privately employed workers but the advantage has narrowed from $1,523 in 2007 to $891 in 2012, adjusted for inflation, federal data show.

25 Oct 2012

Azaya Therapeutics commences ATI-0918 bioequivalence study in ovarian cancer

Azaya Therapeutics, Inc. today announced the initiation of a bioequivalence study of ATI-0918 in patients with ovarian cancer.

25 Oct 2012

Two papers connect lncRNAs to inherited conditions in humans

LncRNAs are long non-coding RNAs that are emerging as important regulators of gene expression in biological processes and diseases. In this issue of the Journal of Clinical Investigation, two papers connect lncRNAs to inherited conditions in humans.

25 Oct 2012

Obese patients more likely to have complications after total knee replacement surgery

Obese patients have a greater risk of complications following total knee replacement surgery, including post-surgical infections, according to a new literature review recently published in the Journal of Bone and Joint Surgery (JBJS).

25 Oct 2012

Paper details new target for anti-cancer drug development

In a new paper released today in Nature, BioFrontiers Institute scientists at the University of Colorado Boulder, Tom Cech and Leslie Leinwand, detailed a new target for anti-cancer drug development that is sitting at the ends of our DNA.

25 Oct 2012

Blistering sunburns and working outdoors associated with two nonmelanoma skin cancers

Researchers at Moffitt Cancer Center, the University of South Florida and the International Agency for Research on Cancer in France have studied the patterns and timing of sunlight exposure and how each is related to two nonmelanoma skin cancers - basal cell carcinoma and squamous cell carcinoma.

25 Oct 2012

AACN selects 7 North Carolina hospitals for nurse leadership and innovation training program

The American Association of Critical-Care Nurses (AACN) has selected seven hospitals in central North Carolina to participate in its new hospital-based nurse leadership and innovation training program.

25 Oct 2012

Patients without lung injury may benefit from mechanical ventilation with lower tidal volume use

Among patients without acute respiratory distress syndrome, protective mechanical ventilation with use of lower tidal volumes (the volume of air inhaled and exhaled during each breath) was associated with better outcomes including less lung injury, lower mortality, fewer pulmonary infections and a shorter hospital length of stay, according to a meta-analysis of previous studies, reported in the October 24/31 issue of JAMA.

25 Oct 2012

New method of oral vaccination could help boost immunity to TB, influenza and C. difficile

Scientists at Royal Holloway, University of London have developed a pioneering new method of oral vaccination which could help boost immunity to TB and influenza, as well as prevent C. difficile for which there is currently no vaccine.

25 Oct 2012

NIH conference to assess GDM screening and diagnostic approaches

Gestational diabetes mellitus (GDM) is a condition in which women without previously diagnosed diabetes exhibit high blood glucose levels during pregnancy (especially during the third trimester of pregnancy). It is defined as carbohydrate intolerance, which is the inability of the body to adequately process carbohydrates (sugars and starches) into energy for the body, that develops or is first recognized during pregnancy.

25 Oct 2012

Lifting weights may play a role in reducing risk of metabolic syndrome

People who lift weights are less likely to have metabolic syndrome—a cluster of risk factors linked to heart disease and diabetes, reports a study in the October issue of The Journal of Strength and Conditioning Research, official research journal of the National Strength and Conditioning Association (NSCA).

25 Oct 2012

Study evaluates frequency and features of very large treatment effects of medical interventions

In an examination of the characteristics of studies that yield large treatment effects from medical interventions, these studies were more likely to be smaller in size, often with limited evidence, and when additional trials were performed, the effect sizes became typically much smaller, according to a study in the October 24/31 issue of JAMA.

25 Oct 2012

Article describes most promising strategies for vascularization of bone tissue substitutes

New, advanced techniques are needed that can mimic the normal blood supply that feeds natural bone to improve the viability and success of restorative procedures to replace damaged or diseased bone tissue using engineered constructs. A comprehensive review article describing the most promising strategies for vascularization of bone tissue substitutes is published in Tissue Engineering, Part B: Reviews, a peer-reviewed journal from Mary Ann Liebert, Inc.

25 Oct 2012

Meat from wild animals is increasingly important in central Africa

Animals like antelope, frogs and rodents may be tricky to catch, but they provide protein in places where traditional livestock are scarce. According to the authors of a new paper in Animal Frontiers, meat from wild animals is increasingly important in central Africa.

25 Oct 2012

Feedback intervention improves hand hygiene compliance in modern hospitals

A major three-year trial led by researchers at UCL, in partnership with the Health Protection Agency, has shown that giving one-to-one feedback to healthcare workers makes them twice as likely to clean their hands or use soap.

25 Oct 2012

Washington Post live holds discussion on NCDs

MSH's "Global Health Impact" blog provides a Storify summary of a Washington Post Live panel discussion on non-communicable diseases (NCDs) that took place last week.

25 Oct 2012

Medical News

Social or daily drinking may be more harmful to brain health

Survey identifies factors that could affect future workforce supply of anesthesiologists

FDA accepts ARIAD’s ponatinib NDA for filing

Hot flashes and night sweats can return after SSRI treatment in women

Roundup: States raise employee insurance contributions to save money; Minn. seeking $80M more for exchange; Selling insurance in malls

Azaya Therapeutics commences ATI-0918 bioequivalence study in ovarian cancer

Two papers connect lncRNAs to inherited conditions in humans

Obese patients more likely to have complications after total knee replacement surgery

Paper details new target for anti-cancer drug development

Blistering sunburns and working outdoors associated with two nonmelanoma skin cancers

AACN selects 7 North Carolina hospitals for nurse leadership and innovation training program

Patients without lung injury may benefit from mechanical ventilation with lower tidal volume use

New method of oral vaccination could help boost immunity to TB, influenza and C. difficile

NIH conference to assess GDM screening and diagnostic approaches

Lifting weights may play a role in reducing risk of metabolic syndrome

Study evaluates frequency and features of very large treatment effects of medical interventions

Article describes most promising strategies for vascularization of bone tissue substitutes

Meat from wild animals is increasingly important in central Africa

Feedback intervention improves hand hygiene compliance in modern hospitals

Washington Post live holds discussion on NCDs

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

The importance of ketones from a clinical and medical perspective

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