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Scientists resolve new molecular circuit controlling cellular metabolism

Cancer, diabetes, and excess body weight have one thing in common: they alter cellular metabolism. Scientists from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg and the Medical University of Vienna together with an international research team have jointly resolved a new molecular circuit controlling cellular metabolism.

15 Oct 2012

Maternal, child health programs must reach poorest families to be successful

"Worldwide, evidence-based interventions are being implemented in an effort to drive down child mortality and there are some signs that they are working," a Lancet editorial states. "However, few countries are on course to meet the targets set by Millennium Development Goal 4," the editorial notes.

15 Oct 2012

Prize-winning study on single-bicycle crashes and accident prevention

Crashes are an unfortunate fact of life for many travelling on our roads and bicycle paths, but how and why they happen is not always well understood. In the Netherlands alone, A&E Departments treat 46,000 injuries sustained in single-bicycle incidents each year, 6000 of which lead to hospital admission. Reducing the number of bicycle accidents is thus good for the public purse as well as for the cyclists themselves.

15 Oct 2012

S. African National AIDS Council CEO speaks to PlusNews about reform, funding

Fareed Abdullah, CEO of the South African National AIDS Council (SANAC), who took office in July, spoke with PlusNews regarding the body's reform, the revival of provincial AIDS councils, resource mobilization, and the appointment of a new board that allows SANAC to operate independently.

15 Oct 2012

Highlights of Mount Sinai research at Neuroscience 2012

Researchers from Mount Sinai School of Medicine are presenting important discoveries on the involvement of the immune system and dopamine cells in the onset of depression at Neuroscience 2012, the Society for Neuroscience's 42nd annual meeting on October 13 -17 in New Orleans, and are available for interviews.

15 Oct 2012

DoD's global health efforts 'difficult to ignore' given department's budget, reach

A report released last week by the Kaiser Family Foundation outlines the U.S. Department of Defense's (DoD) global health work, "presenting the first comprehensive analysis of DoD's activities and budget in this area" and "aiming to contribute to discussions about DoD's role in global health, understandably regarded as controversial by many observers," a Lancet editorial states.

15 Oct 2012

Elekta Synergy system with Agility 160-leaf MLC now available at Radboud

The first of three newly acquired Elekta Synergy treatment systems equipped with Agility 160-leaf multi-leaf collimator (MLC) is now up and running clinically at Radboud University Nijmegen Medical Center - making the clinic the first in the Netherlands to use Agility.

From Elekta 15 Oct 2012

Treatment of OSA could reduce blood pressure in men with hypertension

A new study suggests that when prescribed by physicians in routine practice and used appropriately by patients, treatment for obstructive sleep apnea (OSA) could reduce blood pressure in men with hypertension.

15 Oct 2012

Tanzania investigating circulation of fake HIV drugs, stops local ARV production

BBC News reports on an investigation into the circulation of fake HIV drugs in Tanzania, writing, "Analysts say there is concern about the quality of locally made drugs given widespread corruption in political circles in the East Africa nation."

15 Oct 2012

Duke researchers develop new 3-D tool for heart surgery

A team of researchers from Duke University speaking at the ANESTHESIOLOGY 2012 annual meeting revealed the development of a new 3-D tool that enables trainees in transesophageal echocardiography (TEE) to have real-time instruction in obtaining and interpreting high-quality images of the heart and major vessels - and it's all just a finger swipe away on your Apple iPad.

15 Oct 2012

Researchers identify molecular emergency brake in charge of regulating self-digestion

Almost everything that happens inside a cell, including autophagy, is tightly regulated on a biochemical level. Like that, the cell makes sure that processes only take place when they are needed and that they are shut off when the need has expired. "Inside the cell, there exists a network of molecules. Between them, information is constantly being exchanged," says Schmitz, head of the research group "Systems-oriented Immunology and Inflammation Research" at HZI, who also holds a chair at the Otto von Guericke University in Magdeburg.

15 Oct 2012

Cellectricon settles patent infringement litigation with Fluxion

Cellectricon AB and Fluxion Biosciences today announced that they have settled the patent infringement litigation that Cellectricon commenced against Fluxion in 2009.

From Fluxion Biosciences 15 Oct 2012

Gardasil does not increase sexual activity in girls

The human papillomavirus (HPV) vaccine known as Gardasil is not associated with an increase in pregnancy, sexually transmitted infections, or contraceptive counseling, according to a Kaiser Permanente study published online today in the journal Pediatrics.

15 Oct 2012

Women's health, Medicare and the health law mark tight races in various states

Asked where he would cut the government, Mr. Brown cited President Obama's health care law, which, he said, was crushing Massachusetts businesses. He said the law would remove $700 billion from Medicare, an assertion that Mr. Romney made in last week's presidential debate. "That's the same playbook that Mitt Romney used a week ago tonight," Ms. Warren said. "It was wrong then, it's wrong tonight."

15 Oct 2012

Study examines link between alcohol consumption and AF in patients with cardiovascular disease

An analysis of the association of alcohol consumption with the development of atrial fibrillation (AF) among subjects with coronary heart disease, stroke, diabetes, or other manifestations of cardiovascular disease (CVD) was based on subjects in two large antihypertensive drug treatment trials.

15 Oct 2012

Genzyme announces key data from AUBAGIO Phase III trial on multiple sclerosis

Genzyme, a Sanofi company announced today that key data from the TOWER trial were presented at the 28th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS).

15 Oct 2012

UC Irvine's Program in Geriatrics to reduce risk of elder abuse

UC Irvine's Program in Geriatrics has received a three-year, $1 million grant from the U.S. Administration on Aging to combat elder abuse.

15 Oct 2012

Common genetic polymorphisms can increase risk of autism spectrum disorders

The causes of autism and autism spectrum disorder (ASD) are complex, and contain elements of both nature (genes) and the environment. New research published in BioMed Central's open access journal Molecular Autism shows that common genetic polymorphisms (genetic variation) can add up to an increased risk of ASD.

15 Oct 2012

Merck announces results from odanacatib Phase II trial on post-menopausal osteoporosis

Merck, known as MSD outside the United States and Canada, today announced results from a Phase II trial for odanacatib, an investigational cathepsin K (cat-K) inhibitor in development for the treatment of osteoporosis in post-menopausal women.

15 Oct 2012

Researchers identify new genetic signature for sarcoidosis

Researchers at the University of Illinois Hospital & Health Sciences System have identified a genetic signature that distinguishes patients with complicated sarcoidosis, an inflammatory lung disease that can be fatal, from patients with a more benign form of the disease. The gene signature could become the basis for a simple blood test.

15 Oct 2012