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AKP America commences ART-123 Phase 3 trial in severe sepsis patients with coagulopathy

Asahi Kasei Pharma America Corp. today announced the initiation of an 800-patient Phase 3 clinical trial for ART-123 (recombinant human thrombomodulin, marketed as Recomodulin in Japan) in severe sepsis patients with coagulopathy.

1 Nov 2012

Scientists solve mystery behind what triggers the herpes virus to become active again

The mere mention of the word "herpes" usually conjures negative images and stereotypes, but most people have been infected with some form of the virus. For most, a sore appears, heals and is forgotten, although the virus remains latent just waiting for the right circumstances to come back. Now, the mystery behind what triggers the virus to become active again is closer to being solved thanks to new research published in the Journal of Leukocyte Biology's November 2012 issue.

1 Nov 2012

Watson acquires Actavis

Watson Pharmaceuticals, Inc. today announced that it has completed the acquisition of the Actavis Group for EUR 4.25 billion.

1 Nov 2012

FDA: Ameridose voluntarily recalls all unexpired drug products in circulation

The U.S. Food and Drug Administration announced today that Ameridose, LLC, based in Westborough, Mass., is voluntarily recalling all of its unexpired products in circulation.

1 Nov 2012

Medicare news: Health spending on seniors grew faster in U.S. than Canada; Plan to cut costs on dual eligibles raises questions

A new study finds that U.S. spending grew nearly three times faster since 1980 than Canada's spending on a similar population group.

1 Nov 2012

Recurrence risk can be identified before hepatectomy

Patients who are likely to experience disease recurrence after undergoing hepatectomy for hepatocellular carcinoma can be identified by factors that are available preoperatively, indicate the results of a Hong Kong study.

31 Oct 2012

Prognostic impact of Gleason score modernization undetermined

A review of contemporary grading systems for prostate cancer has found that modernization of the Gleason grading system results in more accurate grading for radical prostatectomy than older systems.

31 Oct 2012

All schoolchildren could be screened for stuttering

A screening model for stuttering could be used to assess all school-age children for the speech disorder, say researchers.

31 Oct 2012

Affordable Medicines Facility improves access to anti-malarials

The Affordable Medicines Facility-malaria has resulted in significant improvements in the availability and price of quality-assured artemisinin-based combination therapies in seven African countries after 1 year, show study findings published in The Lancet.

31 Oct 2012

Gene variant predicts lymphoma treatment response

German researchers have identified a gene variant that significantly influences the outcome of methotrexate therapy for primary central nervous system lymphoma.

31 Oct 2012

Regional anesthesia reduces transfusion risk in knee replacement surgery

Regional anesthesia, compared with general anesthesia, reduces the need for blood transfusions in patients undergoing bilateral total knee replacement, research suggests.

31 Oct 2012

Genetic counseling benefits relatives of schizophrenia patients

Genetic counseling is generally welcomed by the family members of patients with schizophrenia and can provide lasting benefits, say researchers.

31 Oct 2012

Biomarker discovery offers hope for lung cancer blood test

Blood levels of a variant form of the nuclear matrix protein Ciz1 are significantly higher in individuals with early- and late-stage lung cancer than in lung cancer-free individuals, researchers report.

31 Oct 2012

BD prevalence in depression varies according to diagnostic method

The prevalence of bipolar disorder in patients with a major depressive episode varies widely depending on the diagnostic method used, researchers report.

31 Oct 2012

Smoke-free laws lead to fewer heart attacks

A recent decline in the incidence of myocardial infarction in Olmsted County, Minnesota, USA, could be due to the implementation of smoke-free laws, researchers suggest.

31 Oct 2012

Intraoperative cardiac arrest most likely following heavy blood loss

Study results show that although intraoperative cardiac arrest is rare during noncardiac surgery, patients who receive intraoperative blood transfusion are at increased risk for the event.

31 Oct 2012

Weight-management advice needed with cat neutering

Neutered status is one of the most significant factors for obesity in vet-visiting cats in the UK, report researchers, who suggest that weight-management measures should be targeted at owners when their pets are neutered.

31 Oct 2012

Hospice volunteers' satisfaction relies on appreciation, support

The majority of individuals involved with nine Canadian hospice volunteer programs are satisfied with their work, citing the appreciation and gratitude of patients and their families as the most satisfying aspect of volunteering, indicate study results.

31 Oct 2012

‘Off the shelf’ stem cells show promise for perianal fistula

Expanded allogenic adipose-derived stem cells are effective for the treatment of perianal fistula in patients with Crohn’s disease, suggest the results of a phase I/II trial.

31 Oct 2012

Formaldehyde levels ‘concerning’ in US child care facilities

A study of 40 child care facilities in California, USA, has revealed that while levels of most pollutants are not a health concern, those of some are worryingly high.

31 Oct 2012