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N.Y. Times examines why many kidneys available for transplant are discarded

In each of the past five years, more than 2,600 kidneys were recovered and discarded, according to government data.

21 Sep 2012

Strand Life Sciences to validate and commercialize Trovagene's urine-based HPV test

Trovagene, Inc. and Strand Life Sciences Pvt Ltd., of Bangalore, India, completed their agreement to validate and commercialize Trovagene's proprietary urine-based Human Papillomavirus (HPV) test for clinical diagnostic and carrier screening use.

21 Sep 2012

Isolating and concentrating cells from whole blood: an interview with Victor Ugaz

There are several reasons for this. One is because analysis involving different kinds of blood cells may require you to be able to separate red blood cells from white blood cells, or plasma from whole blood etc.

21 Sep 2012

State roundup: HCA fined for kickbacks; Minn. rural health care investigation

The Hospital Corporation of America will pay $16.5 million to settle claims that its subsidiaries had paid a diagnostics firm for referrals, violating federal anti-kickback rules, the Justice Department announced Wednesday. HCA subsidiary Parkridge Medical Center and HCA Physician Services, both provided "financial benefits" to a physician group, Diagnostic Associates of Chattanooga, for referrals to the HCA facilities.

21 Sep 2012

Loss of IGSF1 gene function causes central hypothyroidism

Loss of function in the X-linked immunoglobulin superfamily member 1 (IGSF1) gene causes central hypothyroidism, testicular enlargement, and variable prolactin deficiency, according to data presented at the 82nd Annual Meeting of the American Thyroid Association in Québec City, Québec, Canada.

21 Sep 2012

Caltech biologists gain new insight into migrating cells

At any given moment, millions of cells are on the move in the human body, typically on their way to aid in immune response, make repairs, or provide some other benefit to the structures around them. When the migration process goes wrong, however, the results can include tumor formation and metastatic cancer. Little has been known about how cell migration actually works, but now, with the help of some tiny worms, researchers at the California Institute of Technology (Caltech) have gained new insight into this highly complex task.

21 Sep 2012

ChromaDex announces findings from pTeroPure Phase 2/3 trial on high blood pressure

ChromaDex Corporation announced today findings from a Phase 2/3 trial at the University of Mississippi Medical Center showing its patented nutritional ingredient pTeroPure (pterostilbene) significantly reduced blood pressure in adults.

21 Sep 2012

Iron transport may contribute to diabetes

Scientists have been trying to explain the causes of diabetes for many years. Researchers at the University of Copenhagen and Novo Nordisk A/S have now shown that the increased activity of one particular iron-transport protein destroys insulin-producing beta cells. In addition, the new research shows that mice without this iron transporter are protected against developing diabetes.

21 Sep 2012

Study identifies factors that contribute to solid stress within tumors

It's a high-pressure environment within solid tumors. Abnormal blood and lymphatic vessels cause fluids to accumulate, and the uncontrolled proliferation of cancer cells within limited space leads to the buildup of what is called solid stress.

21 Sep 2012

Mathematical modeling can help treat several diseases

Mathematical modeling being tested by researchers at the School of Science at Indiana University-Purdue University Indianapolis (IUPUI) and the IU School of Medicine has the potential to impact the knowledge and treatment of several diseases that continue to challenge scientists across the world.

21 Sep 2012

Research focuses on HER2 cancers

As scientists continue to map breast cancer's complex genetic makeup, research at Michigan State University could lead to better diagnoses and new treatment targets.

21 Sep 2012

Scientists describe development of tantalum nanotube materials

In an advance toward a new generation of improved hip and other joint replacements, scientists are describing development of a potential implant material that flexes more like natural bone, fosters the growth of bone that keeps implants firmly in place and is less likely to fail and require repeat surgery. Their study on these so-called tantalum nanotube materials appears in ACS Applied Material & Interfaces.

21 Sep 2012

Childhood emotional neglect may increase risk of stroke in later adulthood

The results from a new study by neurological researchers from the Rush Alzheimer's Disease Center at Rush University Medical Center suggest that people who were emotionally neglected as children may have a higher risk of stroke in later adulthood.

21 Sep 2012

Alabama voters approve moving money from state trust fund to balance budget

Alabama voters decided by a 2-to-1 margin Tuesday to avoid dramatic cuts in state government by withdrawing $437 million from a state trust fund to help balance the General Fund budget for the next three years. State Health Officer Don Williamson, who oversees the state Medicaid program, said it will still have to make $20 million to $40 million in cuts to live within the new year's budget, but that will be much less painful than the massive cuts that were forecast.

21 Sep 2012

Biovest seeks EMA approval for BiovaxID to treat non-Hodgkin's lymphoma

Biovest International, Inc., a majority-owned subsidiary of Accentia Biopharmaceuticals, Inc., today reported milestone achievements advancing BiovaxID, Biovest's personalized cancer vaccine for the treatment of non-Hodgkin's lymphoma, including a recently conducted regulatory meeting with the European Medicines Agency (EMA) and the appointment of a key contributor to the Human Genome Project to its Scientific Advisory Board.

21 Sep 2012

Study of spinal injury data may help surgeons treat injured soldiers or civilians

Spinal injuries are among the most disabling conditions affecting wounded members of the U.S. military. Yet until recently, the nature of those injuries had not been adequately explored.

21 Sep 2012

First extensive analysis of Allen Human Brain Atlas

Scientists at the Allen Institute for Brain Science reported in the latest issue of the journal Nature that human brains share a consistent genetic blueprint and possess enormous biochemical complexity. The findings stem from the first deep and large-scale analysis of the vast data set publicly available in the Allen Human Brain Atlas.

21 Sep 2012

Researchers develop cranial neural crest cell lines

Researchers have successfully developed a stable population of neural crest cells derived from mice that can be grown in large quantities in the laboratory and that demonstrates the potential to develop into many different cell types needed throughout the body.

21 Sep 2012

Mosquitoes show signs of behavior change in response to bed net use, study says

About three years after two villages in Benin began using insecticide-treated bed nets to help prevent malaria, mosquitoes in the area changed their biting habits, so their "hours of 'peak aggression' [went] from 2 a.m. or 3 a.m. to around 5 a.m." and "in one village, the proportion of mosquito bites inflicted outdoors rose," according to a study published in the Journal of Infectious Diseases, Reuters reports.

21 Sep 2012

FDA approves Acton’s AEROSPAN sNDA to treat asthma

Acton Pharmaceuticals, Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved the sNDA (Supplemental New Drug Application) for AEROSPAN (flunisolide HFA, 80 mcg) Inhalation Aerosol, a hydrofluoroalkane (HFA) orally inhaled corticosteroid indicated for the maintenance treatment of asthma as a prophylactic therapy in adult and pediatric patients 6 years of age and older.

21 Sep 2012