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Book examines highly complex structures of synaptic regions

Synapses are bulbous structures where two neurons communicate. Neurotransmitter molecules released from the presynaptic terminal of one neuron diffuse to the postsynaptic terminal on the other, binding to receptors that lead to propagation or modulation of the signal.

7 Sep 2012

Untreated severe OSA may increase risk of cardiovascular death in the elderly

Untreated severe obstructive sleep apnea (OSA) is associated with an increased risk of cardiovascular mortality in the elderly, and adequate treatment with continuous positive airway pressure (CPAP) may significantly reduce this risk, according to a new study from researchers in Spain.

7 Sep 2012

Roundup: Judge keeps Calif. prison health care under fed control; Hospital mergers possible in Kan., Wis., Minn.

A judge has again rejected the state's request for a speedy end to federal control of prison health care. In an order issued Wednesday, U.S. District Judge Thelton Henderson said he would require tougher reviews than the state wanted before agreeing to dissolve the receivership that has run inmate medical care for six years.

7 Sep 2012

Kalidex announces presentation of data on KPI-10 against MDR strains at ICAAC

Kalidex Pharmaceuticals, a privately-held anti-infective company, today announced the presentation of data on its lead development candidate KPI-10, a broad spectrum, next-generation fluoroquinolone, at the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in San Francisco, September 9 through 12.

7 Sep 2012

Interleukin-18 plays a key role in inflammation

The naturally occurring cytokine interleukin-18, or IL-18, plays a key role in inflammation and has been implicated in serious inflammatory diseases for which the prognosis is poor and there are currently limited treatment options.

7 Sep 2012

All seniors can enjoy benefits of exercise: Study

A study carried out by Dr. Louis Bherer, PhD (Psychology), Laboratory Director and Researcher at the Institut universitaire de g-riatrie de Montr-al (IUGM), an institution affiliated with Universit- de Montr-al, has shown that all seniors, even those considered frail, can enjoy the benefits of exercise in terms of their physical and cognitive faculties and quality of life and that these benefits appear after only three months.

7 Sep 2012

Absence of Puma and Bim protein leads to autoimmune diseases

Researchers at the Walter and Eliza Hall Institute have discovered that a pair of molecules work together to kill so-called 'self-reactive' immune cells that are programmed to attack the body's own organs.

7 Sep 2012

Distribution infrastructure, effective education important for success of micronutrient powders to treat childhood anemia

In this post in the New York Times' "Opinionator" blog, journalist Sam Loewenberg examines the administration of micronutrient powders as a treatment option for anemia, "one of the most pervasive problems affecting the world's children, and one that goes largely unaddressed."

7 Sep 2012

Study finds PARP1 and EZH2 as potential therapeutic targets for small cell lung cancer

Newly discovered molecular differences between small cell lung cancer and nonsmall cell lung cancer have revealed PARP1 and EZH2 as potential therapeutic targets for patients with small cell lung cancer, according to the results of a study published in Cancer Discovery, a journal of the American Association for Cancer Research.

7 Sep 2012

Wnt5a protein essential in repairing the intestine's inner lining

Scientists at Washington University School of Medicine in St. Louis have identified a protein essential to repairing the intestine's inner lining.

7 Sep 2012

New findings establish connection between microRNAs and cellular metabolism

New findings establish a connection between microRNAs and cellular metabolism, suggesting that a drug designed to inhibit these tiny molecules -- once considered to be "junk" DNA -- would have a positive effect against obesity.

7 Sep 2012

Researchers turn skin cells into embryonic Sertoli-like cells

Using a stepwise trans-differentiation process, Whitehead Institute researchers have turned skin cells into embryonic Sertoli-like cells.

7 Sep 2012

Longer looks: Insurers balk at price of new asthma relief; Despite health law, costs still overwhelming for some patients

For two decades, Patricia DiGiusto struggled with severe asthma. Powerful medications and frequent use of her inhaler could not prevent repeated trips to the emergency room. ... Two years ago, Ms. DiGiusto's doctor told her about a new procedure called bronchial thermoplasty, the first non-drug therapy approved by the Food and Drug Administration for patients with severe asthma.

7 Sep 2012

Association between childhood sexual abuse and heart attacks among men

Men who experienced childhood sexual abuse are three times more likely to have a heart attack than men who were not sexually abused as children, according to a new study from researchers at the University of Toronto. The researchers found no association between childhood sexual abuse and heart attacks among women.

7 Sep 2012

Clathrin protein plays a key role in cell division

A protein called "clathrin," which is found in every human cell and plays a critical role in transporting materials within them, also plays a key role in cell division, according to new research at the University of California, San Francisco.

7 Sep 2012

Doctor and pharmacy shoppers at increased risk for drug-related death

A published study conducted by researchers at West Virginia University has found that doctor and pharmacy shoppers are at a greater risk for drug-related death.

7 Sep 2012

Small weight gain enough to increase a college student's systolic blood pressure

As a college student, you may be happy simply not to have gained the "Freshman 15." But a University of Illinois study shows that as little as 1.5 pounds per year is enough to raise blood pressure in that age group, and the effect was worse for young women.

7 Sep 2012

Researchers discover genetic cause of hereditary spastic ataxia

Researchers from the Guy Rouleau Laboratory affiliated with the CHUM Research Centre and the CHU-Sainte-Justine Research Centre have discovered the genetic cause of a rare disease reported only in patients originating from Newfoundland: hereditary spastic ataxia (HSA).

7 Sep 2012

Durata completes target enrollment in dalbavancin Phase 3 trials for abSSSI

Durata Therapeutics today announced that it has completed its target enrollment for DISCOVER 1 ("Dalbavancin for Infections of the Skin COmpared to Vancomycin at an Early Response"), one of two ongoing, global, Phase 3 clinical trials of Durata's lead product candidate, dalbavancin, under investigation for the treatment of acute bacterial skin and skin structure infections (abSSSI).

7 Sep 2012

Longitudinal research confirms correlation between popularity and smoking

New research from the University of Southern California (USC) and University of Texas finds that popular students in seven Southern California high schools are more likely to smoke cigarettes than their less popular counterparts.

7 Sep 2012