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UCSD evaluates safety and tolerability of dexanabinol in Phase I brain cancer study

Researchers at University of California, San Diego Moores Cancer Center are evaluating the safety and tolerability of a synthetic cannabinoid called dexanabinol (ETS2101). Delivered as a weekly intravenous infusion, the drug is being tested in patients with all forms of brain cancer, both primary and metastatic.

26 Sep 2012

New computer program predicts most stable structures of nanometer-sized collagen

The human body is proficient at making collagen. And human laboratories are getting better at it all the time. In a development that could lead to better drug design and new treatments for disease, Rice University researchers have made a major step toward synthesizing custom collagen. Rice scientists who have learned how to make collagen - the fibrous protein that binds cells together into organs and tissues - are now digging into its molecular structure to see how it forms and interacts with biological systems.

26 Sep 2012

New insights into filaminopathies

New insights into certain muscle diseases, the filaminopathies, are reported by an international research team led by Dr. Rudolf Andre Kley of the RUB's University Hospital Bergmannsheil in the journal Brain.

26 Sep 2012

Study finds risk factors for weight problems among children in the US and England

With ties to diabetes, hypertension, and high cholesterol, childhood obesity in wealthy countries is certainly of growing concern to researchers. A new study explores the ties between childhood weight problems, socioeconomic status, and nationality and finds that race, ethnicity, and immigrant status are risk factors for weight problems among children in the US and England.

26 Sep 2012

Two tiny RNA molecules play a key role in pathological heart growth and failure

Cardiac stress, for example a heart attack or high blood pressure, frequently leads to pathological heart growth and subsequently to heart failure. Two tiny RNA molecules play a key role in this detrimental development in mice, as researchers at the Hannover Medical School and the Göttingen Max Planck Institute for Biophysical Chemistry have now discovered.

26 Sep 2012

Roundup: Calif. mental hospitals released from fed oversight; Kansas hospitals cooperate to recruit rural docs; Va. abortion law questions

A U.S. District Court judge Monday released the state's mental hospitals from federal oversight on all but one issue -- a significant step in ending a costly six-year reform effort. The extensive court-supervised changes were imposed on four hospitals in 2006 as part of a settlement to a lawsuit by the U.S. Department of Justice. The department alleged that the state was violating patients' civil rights by heavily drugging and improperly restraining them and failing to provide appropriate treatment.

26 Sep 2012

Warfarin therapy should not be stopped completely after GI bleeding

The decision to not resume warfarin therapy following a gastrointestinal bleeding event is linked to an increased risk for thrombosis and mortality, researchers suggest.

25 Sep 2012

Three-factor tool could be all you need to assess surgery risk

A simple tool involving less than six variables to measure surgical outcomes could be all that is needed to predict inpatient mortality, show US study results.

25 Sep 2012

Success rates affect patient preferences for one or two root canal visits

The potential success rate of root canal treatment affects whether patients would prefer to complete it in one or two visits to the dentist, indicate study results.

25 Sep 2012

Cochlear implant an option for unhappy stapes patients

Cochlear implantation is a safe and effective treatment option for patients with far advanced otosclerosis who have not benefitted from stapedectomy, report US researchers.

25 Sep 2012

Armband labeling could prevent DNR confusion

Implementation of an electronic ordering and armband labeling process for patients with Do Not Resuscitate orders improved correct documentation of their wishes as well as physicians’ ability to recognize and act on them during a cardiac arrest scenario, report US researchers.

25 Sep 2012

Daytime oxygen link to poor sleep in COPD

Patients with chronic obstructive pulmonary disease experience poorer sleep quality than those without the disease, say the authors of an Irish study.

25 Sep 2012

Maternal obstetric problems linked to schizophrenia risk

Certain maternal pregnancy complications are associated with an increased risk for schizophrenia spectrum psychoses among individuals at high genetic risk for the condition, Finnish research shows.

25 Sep 2012

Suicide attempts common in bipolar disorder inpatients

Results from a Norwegian study show that the prevalence of attempted suicide is high among inpatients with bipolar disorder, with nearly half of patients having attempted to take their own lives at least once.

25 Sep 2012

$Ultrasound effective for visualizing fractures in children$