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FDA extends action date for Pfizer’s tofacitinib NDA review

Pfizer Inc. announced today that the U.S. Food and Drug Administration (FDA) has extended the action date by three months for the New Drug Application (NDA) for tofacitinib, an investigational oral treatment for adults with moderately to severely active rheumatoid arthritis (RA).

22 Aug 2012

Study finds 'inconclusive' evidence to support use of WHO-backed drug to prevent hemorrhage during labor

"The World Health Organization [WHO] should review its approval of a drug used to prevent life-threatening bleeding in women in childbirth because there is not enough evidence that it is effective," according to a study published Monday in the Journal of the Royal Society of Medicine, Reuters reports.

22 Aug 2012

Reasoning and behavioral control dependent on different regions of frontal lobes

The frontal lobes are the largest part of the human brain, and thought to be the part that expanded most during human evolution. Damage to the frontal lobes-which are located just behind and above the eyes-can result in profound impairments in higher-level reasoning and decision making. To find out more about what different parts of the frontal lobes do, neuroscientists at the California Institute of Technology (Caltech) recently teamed up with researchers at the world's largest registry of brain-lesion patients.

22 Aug 2012

Study identifies how genetic mutations in the nervous system cause Duane Syndrome

A research team from King's College London and the University of Exeter Medical School has identified how a genetic mutation acts during the development of nerves responsible for controlling eye muscles, resulting in movement disorders such as Duane Syndrome, a form of squint.

22 Aug 2012

Corporate power presents a major threat to public health

Professor Gerard Hastings from the Institute for Social Marketing at the University of Stirling argues that marketing by multinational corporations "threatens our mental wellbeing, exacerbates inequalities, and encourages unsustainable consumption."

22 Aug 2012

CIRT to determine whether methotrexate can reduce heart attacks, strokes and CVD deaths

An international multi-site trial has launched to determine whether a common anti-inflammatory drug can reduce heart attacks, strokes, and deaths due to cardiovascular disease in people at high risk for them. This study is being supported by the National Heart, Lung, and Blood Institute (NHLBI), a part of the National Institutes of Health.

22 Aug 2012

Poll finds Calif. voters strongly support federal health law; Montana lawmakers consider Medicaid expansion

States are confronting a bevy of issues in implementing the health care law including gauging public support for the law, fights over a contraception coverage mandate, expanding Medicaid and assessing the Medicare prescription drug "doughnut hole."

22 Aug 2012

NIAID announces 14 grants for basic research to identify new HIV vaccine approaches

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has awarded 14 grants totaling $7.8 million in first-year funding for basic research to identify new approaches for designing a safe and effective HIV vaccine.

22 Aug 2012

Working memory capacity in patients with Parkinson's can be improved with sleep

People with Parkinson's disease performed markedly better on a test of working memory after a night's sleep, and sleep disorders can interfere with that benefit, researchers have shown.

22 Aug 2012

Study analyzes association between antibiotic use and body mass starting in infancy

Treating very young infants with antibiotics may predispose them to being overweight in childhood, according to a study of more than 10,000 children by researchers at the NYU School of Medicine and the NYU Wagner School of Public Service and published in the online August 21, 2012, issue of the International Journal of Obesity.

22 Aug 2012

Research explores impact of radiotherapy in older women with low risk of breast cancer recurrence

A Rhode Island Hospital radiation oncologist says in a new editorial that research exploring the impact of radiotherapy in older women with low risk of breast cancer recurrence has little effect on actual clinical decisions.

22 Aug 2012

Sotera Wireless receives FDA 510(k) clearance for ViSi Mobile System

Sotera Wireless, Inc. announced today that it has received 510(k) clearance from the United States Food and Drug Administration (FDA) for its full ViSi Mobile System and is commencing sales to hospitals nationwide.

22 Aug 2012

VolitionRX to initiate NuQ blood-based tests in colorectal cancer clinical trial

VolitionRX Limited, a life sciences company focused on developing blood-based diagnostic tests, announces that its subsidiary Belgian Volition has signed an agreement with the Biobank of CHU UCL Mont-Godinne, an academic hospital in Yvoir, Belgium.

22 Aug 2012

Chemists develop new lab test to examine how DNA damage disrupts protein synthesis

Transcription is a cellular process by which genetic information from DNA is copied to messenger RNA for protein production. But anticancer drugs and environmental chemicals can sometimes interrupt this flow of genetic information by causing modifications in DNA.

22 Aug 2012

FDA committee to review NPS’ Gattex NDA in October

NPS Pharmaceuticals, Inc., a specialty pharmaceutical company developing therapeutics for rare gastrointestinal and endocrine disorders, today announced that the U.S. Food and Drug Administration (FDA) has notified the Company that its New Drug Application (NDA) for Gattex (teduglutide) will be discussed at the Gastrointestinal Drugs Advisory Committee meeting scheduled for October 16, 2012.

22 Aug 2012

Scientists unravel how brain cells encode pronunciation of individual vowels in speech

Diagnosed with Lou Gehrig's disease at 21, British physicist Stephen Hawking, now 70, relies on a computerized device to speak. Engineers are investigating the use of brainwaves to create a new form of communication for Hawking and other people suffering from paralysis. -Daily Mail

22 Aug 2012

African Development Bank report compares, analyzes African countries' performance in water, sanitation sector

"According to a new African Development Bank report that compares and analyzes the performance of sub-Saharan African countries in the water and sanitation sector," "the two major factors why progress on meeting water and sanitation-related development goals across sub-Saharan Africa is largely uneven" are "differences in financial and operational capacities among governments," the Devex "Development Newswire" reports.

22 Aug 2012

RasGas establishes heart safe workplace with installation of LIFEPAK CR Plus AEDs

Physio-Control, Inc., a provider of emergency medical response solutions worldwide, today announced that global energy supplier RasGas Company Limited (RasGas) has established a heart safe workplace with the installation of LIFEPAK CR Plus automated external defibrillators (AEDs).

22 Aug 2012

Healthcare announces important changes to the U.S. product label for Optison

GE Healthcare today announced important changes to the U.S. product label for Optison (Perflutren Protein-Type A Microspheres Injectable Suspension, USP), a contrast agent that may improve the visualization of the left ventricular border - an area of the heart that is critical to see in order to diagnose certain heart diseases such as hypertrophic cardiomyopathy.

22 Aug 2012

GM-CSF depletion suppresses pain in people with arthritis-related conditions

The research relates to a family of molecules firstly discovered in Melbourne that applied to blood cell development. One of these, granulocyte macrophage colony-stimulating factor or GM-CSF, acts as a messenger between cells acting at a site of inflammation.

22 Aug 2012

Medical News

FDA extends action date for Pfizer’s tofacitinib NDA review

Study finds 'inconclusive' evidence to support use of WHO-backed drug to prevent hemorrhage during labor

Reasoning and behavioral control dependent on different regions of frontal lobes

Study identifies how genetic mutations in the nervous system cause Duane Syndrome

Corporate power presents a major threat to public health

CIRT to determine whether methotrexate can reduce heart attacks, strokes and CVD deaths

Poll finds Calif. voters strongly support federal health law; Montana lawmakers consider Medicaid expansion

NIAID announces 14 grants for basic research to identify new HIV vaccine approaches

Working memory capacity in patients with Parkinson's can be improved with sleep

Study analyzes association between antibiotic use and body mass starting in infancy

Research explores impact of radiotherapy in older women with low risk of breast cancer recurrence

Sotera Wireless receives FDA 510(k) clearance for ViSi Mobile System

VolitionRX to initiate NuQ blood-based tests in colorectal cancer clinical trial

Chemists develop new lab test to examine how DNA damage disrupts protein synthesis

FDA committee to review NPS’ Gattex NDA in October

Scientists unravel how brain cells encode pronunciation of individual vowels in speech

African Development Bank report compares, analyzes African countries' performance in water, sanitation sector

RasGas establishes heart safe workplace with installation of LIFEPAK CR Plus AEDs

Healthcare announces important changes to the U.S. product label for Optison

GM-CSF depletion suppresses pain in people with arthritis-related conditions

The importance of ketones from a clinical and medical perspective

How Programmable Nanobiology Could Drive the Fifth Industrial Revolution

Dr. Anthony Grice

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