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Inhibiting over-production of Panx1 protein can treat melanoma

New research from Western University, Canada, has identified a potential new target for the treatment of melanoma, the deadliest of all skin cancers. Silvia Penuela and Dale Laird discovered a new channel-forming protein called Pannexin (Panx1) that is expressed in normal levels on the surface of healthy skin cells.

16 Aug 2012

Delaying gratification at 4 years of age may affect weight later in life

As adults, we know that self-control and delaying gratification are important for making healthful eating choices, portion control, and maintaining a healthy weight. However, exhibiting these skills at a young age actually may affect weight later in life. A new study scheduled for publication in The Journal of Pediatrics finds that delaying gratification longer at 4 years of age is associated with having a lower body mass index (BMI) 30 years later.

16 Aug 2012

Researchers discover why people with sickle cell disease get milder cases of malaria

Researchers at Duke University Medical Center may finally have discovered why people with sickle cell disease get milder cases of malaria than individuals who have normal red blood cells.

16 Aug 2012

Scientists devise new fluorescent probes to diagnose neurodegenerative diseases

Sticky plaques of proteins called amyloids mark several different, though related degenerative brain diseases including Alzheimer's, Parkinson's and Creutzfeld-Jacobs. The symptoms of these disorders overlap and methods to diagnose and monitor them are not very advanced.

16 Aug 2012

Calorie Calculator can help assess impact of health policy choices on childhood obesity

Dieters often use online calorie calculators to stay true to their weight-loss plan. Translating the concept to the population health arena, researchers at Columbia University's Mailman School of Public Health created the Caloric Calculator to help policymakers, school district administrators, and others assess the potential impact of health policy choices on childhood obesity.

16 Aug 2012

Cedars-Sinai's ICT-107 doubles median survival of patients with malignant brain tumor

An experimental immune-based therapy more than doubled median survival of patients diagnosed with the most aggressive malignant brain tumor, Cedars-Sinai Medical Center researchers reported in Cancer Immunology, Immunotherapy, published online Aug. 3.

16 Aug 2012

CYCLOPS genes may serve as targets for cancer therapies

The genomic tumult within tumor cells has provided scientists at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard with clues to an entirely new class of genes that may serve as an Achilles' heel for many forms of cancer.

16 Aug 2012

Combination of exercise and S-nitrosoglutathione improves recovery from stroke

In a study published in the current issue of Restorative Neurology and Neuroscience scientists report that a therapy combining exercise with the neurovascular protective agent S-nitrosoglutathione (GSNO) improved recovery from stroke in a rat model. GSNO is a compound found naturally in the body and it has no known side effects or toxicity.

16 Aug 2012

UCLA performs first transcatheter aortic valve replacement using new device

UCLA has performed its first transcatheter aortic valve replacement (TAVR), using a new device approved by the U.S. Food and Drug Administration to replace an aortic valve in a patient who was not a candidate for open-heart surgery. The procedure took place August 9th.

16 Aug 2012

Brain changes can occur after long-term methadone treatment

Long-term methadone treatment can cause changes in the brain, according to recent studies from the Norwegian Institute of Public Health. The results show that treatment may affect the nerve cells in the brain. The studies follow on from previous studies where methadone was seen to affect cognitive functioning, such as learning and memory.

16 Aug 2012

Women with hypertension or obesity more likely to experience sleep apnoea

New research from Umeå and Uppsala universities has found high rates of sleep apnoea in women, despite the condition usually being regarded as a disorder predominantly of males.

16 Aug 2012

Diffusion Pharmaceuticals receives new U.S. patents for trans sodium crocetinate

Diffusion Pharmaceuticals LLC, a biotechnology company focused on innovative cancer treatments, today announced that the U.S. Patent and Trademark Office has granted it patent numbers 7919527 and 8030350, entitled "Bipolar Trans Carotenoids Salts and Their Uses" and "Trans Carotenoids, Their Synthesis and Uses," respectively.

16 Aug 2012

Maternal healthcare providers in developing world must be trained to show respect, compassion

"In teaching nurses and midwives in the developing world to care for their patients, a core tenet is that respectful care is quality care," Catherine Carr, senior maternal health advisor for the Jhpiego/MCHIP-Maternal and Child Health Integrated Program, writes in this post in Huffington Post's "Global Motherhood" blog.

16 Aug 2012

Genocea commences GEN-003 Phase 1/2a study in moderate-to-severe HSV-2 infection

Genocea Biosciences announced today that it has initiated a Phase 1/2a clinical study with its lead candidate, GEN-003. GEN-003 is an investigational vaccine designed to stimulate T cell and B cell immune responses to potentially reduce the frequency and severity of clinical outbreaks associated with moderate-to-severe Herpes Simplex Virus type 2 (HSV-2) infection.

16 Aug 2012

Scientists reveal how TREX proteins act as passport for transfer of cell blueprints

Decoded process could hold the key to future treatments for a wide range of chronic health problems including Motor Neuron Disease, myotonic dystrophy and a wide range of cancers, University of Sheffield scientists have revealed.

16 Aug 2012

Thomson Reuters welcomes GenoSpace to Life Sciences Partner Ecosystem

The Intellectual Property & Science business of Thomson Reuters, the world's leading provider of intelligent information for businesses and professionals, today announced that GenoSpace joined its Life Sciences Partner Ecosystem.

16 Aug 2012

Implanted cells' therapeutic properties depend on their shape

Tissue implants made of cells grown on a sponge-like scaffold have been shown in clinical trials to help heal arteries scarred by atherosclerosis and other vascular diseases. However, it has been unclear why some implants work better than others.

16 Aug 2012

Technion researchers build pancreatic tissue with insulin-secreting cells to treat diabetes

Technion researchers have built pancreatic tissue with insulin-secreting cells, surrounded by a three-dimensional network of blood vessels. The engineered tissue could pave the way for improved tissue transplants to treat diabetes.

16 Aug 2012

Science Exchange launches Reproducibility Initiative

Science Exchange, in partnership with the open-access publisher PLOS and open data repository figshare, announced today the launch of the Reproducibility Initiative - a new program to help scientists, institutions and funding agencies validate their critical research findings.

16 Aug 2012

3SBio files APX001 IND application with SFDA in China

Apexigen, Inc., an emerging biopharmaceutical company focused on the discovery and development of monoclonal antibody therapeutics, announced today that its partner, 3SBio [SSRX] of Shenyang, China, filed an Investigational New Drug (IND) application for APX001, also known as SSS07, with the State Food and Drug Administration (SFDA) in China.

16 Aug 2012

Medical News

Inhibiting over-production of Panx1 protein can treat melanoma

Delaying gratification at 4 years of age may affect weight later in life

Researchers discover why people with sickle cell disease get milder cases of malaria

Scientists devise new fluorescent probes to diagnose neurodegenerative diseases

Calorie Calculator can help assess impact of health policy choices on childhood obesity

Cedars-Sinai's ICT-107 doubles median survival of patients with malignant brain tumor

CYCLOPS genes may serve as targets for cancer therapies

Combination of exercise and S-nitrosoglutathione improves recovery from stroke

UCLA performs first transcatheter aortic valve replacement using new device

Brain changes can occur after long-term methadone treatment

Women with hypertension or obesity more likely to experience sleep apnoea

Diffusion Pharmaceuticals receives new U.S. patents for trans sodium crocetinate

Maternal healthcare providers in developing world must be trained to show respect, compassion

Genocea commences GEN-003 Phase 1/2a study in moderate-to-severe HSV-2 infection

Scientists reveal how TREX proteins act as passport for transfer of cell blueprints

Thomson Reuters welcomes GenoSpace to Life Sciences Partner Ecosystem

Implanted cells' therapeutic properties depend on their shape

Technion researchers build pancreatic tissue with insulin-secreting cells to treat diabetes

Science Exchange launches Reproducibility Initiative

3SBio files APX001 IND application with SFDA in China

The importance of ketones from a clinical and medical perspective

How Programmable Nanobiology Could Drive the Fifth Industrial Revolution

Dr. Anthony Grice

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