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AVEO commences AV-203 Phase 1 study in advanced solid tumors

AVEO Oncology today announced the initiation of a Phase 1 study examining the safety and preliminary efficacy of AV-203 along with exploratory biomarkers in patients with advanced solid tumors.

23 May 2012

USPTO issues patent to MicuRx’s MRX-I antibacterial agent

MicuRx Pharmaceuticals, Inc., a privately-held biopharmaceutical company developing next-generation antibiotics, today announced that the U.S. Patent and Trademark Office (USPTO) issued a composition of matter patent covering its clinical candidate, MRX-I. MRX-I is a novel antibacterial oxazolidinone that targets infections due to multi-drug resistant Gram-positive pathogens.

23 May 2012

Scientists may be step closer to developing new therapy for AML

Scientists at Virginia Commonwealth University Massey Cancer Center may be one step closer to developing a new therapy for acute myeloid leukemia (AML) after discovering that the targeted agents obatoclax and sorafenib kill leukemia cells much more effectively when combined than when the drugs are administered individually.

23 May 2012

Studies examine effectiveness of CPAP in reducing risk of cardiovascular outcomes linked with OSA

Two studies that included adults with obstructive sleep apnea examined the effectiveness of reducing the risk of cardiovascular outcomes, including high blood pressure, by treatment with continuous positive airway pressure (CPAP), according to the articles in the May 23/30 issue of JAMA.

23 May 2012

Phi29 DNA packaging nanomotor connector can aid in early disease diagnosis

A new study led by University of Kentucky researchers shows a new way to precisely detect a single chemical at extremely low concentrations and high contamination.

23 May 2012

HeartWare receives expanded European label for Ventricular Assist System

HeartWare International, Inc., a leading innovator of less invasive, miniaturized circulatory support technologies revolutionizing the treatment of advanced heart failure, today announced that it has received an expanded European label for long-term use of the HeartWare Ventricular Assist System in all patients at risk of death from refractory, end-stage heart failure.

23 May 2012

Study shows how streamlined patient pathways may improve efficiency of healthcare delivery

The Alliance for Home Health Quality and Innovation (the Alliance) today released research detailing the care pathways patients receive for three distinct episode types: post-acute, pre-acute and non-post-acute.

23 May 2012

Severe hypersensitivity reactions to anti-HIV drug occur through autoimmune mechanism

Potentially severe hypersensitivity reactions to the anti-HIV drug abacavir occur through an autoimmune mechanism, resulting from the creation of drug-induced immunogens that are attacked by the body's immune system, according to a study published online by the journal AIDS, official journal of the International AIDS Society.

23 May 2012

SOAPware releases new product that interfaces with Inmediata's PM module

SOAPware, Inc., a leading developer of certified Electronic Medical Records (EMR/EHR) and Practice Management (PM) software, is pleased to announce the release of a newly updated SOAPwareXchange product which interfaces with Inmediata's PM module.

23 May 2012

Astrocytes appear to retaliate against AD

When brain cells start oozing too much of the amyloid protein that is the hallmark of Alzheimer's disease, the astrocytes that normally nourish and protect them deliver a suicide package instead, researchers report.

23 May 2012

Few new chemicals are in development for malaria vector control

"This issue has been building for some time. It is really no surprise as insects have become resistant to nearly all insecticides given time and selection pressure. Few new chemicals are in development for malaria vector control, because there is little profit to be made by the poorest of the world's poor — who feel the brunt of the malaria burden.

23 May 2012

Study shows how chromosomal mutation likely contributes to early development of prostate cancer

Up to half of all prostate cancer cells have a chromosomal rearrangement that results in a new "fusion" gene and formation of its unique protein -- but no one has known how that alteration promotes cancer growth. Now, Weill Cornell Medical College researchers have found that in these cancer cells, the 3-D architecture of DNA, wrapped up in a little ball known as a chromatin, is warped in such a way that a switch has been thrown on thousands of genes, turning them on or off to promote abnormal, unchecked growth. Researchers also found that new chromosomal translocations form, further destabilizing the genome.

23 May 2012

Researchers to initiate Crenezumab clinical trial to treat Alzheimer's

After an announcement by federal officials approving clinical trials for the drug Crenezumab, researchers searching for a way to treat Alzheimer's Disease are gearing up for a rare study that will allow them to test a therapy for a genetically predestined disease -- before its onset.

23 May 2012

FDA clears ETView’s VivaSight-DL Airway Management System

ETView today announced that the company has received clearance of a 510(k) Pre-Marketing Notification Application with the US Food and Drug Administration.

23 May 2012

Researchers generate neuronal cells from patients with Fragile X syndrome

Researchers at the Hebrew University of Jerusalem have achieved, for the first time, the generation of neuronal cells from stem cells of Fragile X patients. The discovery paves the way for research that will examine restoration of normal gene expression in Fragile X patients.

23 May 2012

First Edition: May 23, 2012

Today's headlines include reports about the CBO's dire predictions about a possible recession as well as details about how health policy is handled in new presidential campaign ads.

23 May 2012

Study provides new clues about health-damaging molecular changes by eating high-fat foods

A University of Michigan Health System study provides new clues about the health-damaging molecular changes set in motion by eating high-fat foods.

23 May 2012

FDA approves TMI’s Glider PTCA Catheter

TriReme Medical, Inc. (TMI) today announced approval by the U.S. Food and Drug Administration (FDA) of the Glider PTCA Catheter, indicated for treating the stenotic portion of coronary arteries or bypass grafts to improve myocardial perfusion.

23 May 2012

Tri-City Medical Center leading the way with robotically enhanced spine surgery

Tri-City Medical Center, one of just 10 hospitals nationwide performing robotic spine surgery using the Mazor Renaissance guidance system, is now one of the first hospitals worldwide to use an enhancement to that system that allows surgeons to immediately verify the placement of implants, significantly diminishing the need for follow-up procedures.

23 May 2012

Panel of HuCAL Anti-Drug Antibodies to be launched by AbD Serotec

MorphoSys AG (FSE: MOR; Prime Standard Segment, TecDAX) announced today that its division for research and diagnostic antibodies, AbD Serotec, will launch a series of novel anti-drug antibodies (ADAs) to strengthen its position as a leading provider of diagnostic reagents.

23 May 2012