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Nature outlook examines fight against malaria in Uganda

Nature Outlook examines the fight against malaria in Uganda. "Uganda's tragic failure to abate malaria has numerous political, geographic, economic and social factors -- and illustrates the reality that it takes more than scientific breakthroughs and cheap drugs to solve this persistent menace," according to the article. Nat

27 Apr 2012

Gas NO plays a fundamental regulatory role in controlling bacterial function

Bacteria provide a well-known playground for scientists and the evolution of these earliest life forms has shed important perspective on potential therapies for some of the most common, deadly diseases. Researchers at Case Western Reserve University School of Medicine have now discovered that, the gas nitric oxide (NO), produced in all cells of the human body for natural purposes, plays a fundamental regulatory role in controlling bacterial function, via a signaling mechanism called S-nitrosylation (SNO), which binds NO to protein molecules.

27 Apr 2012

Blogs examine malaria fight in recognition of World Malaria Day

Wednesday, April 25, marked World Malaria Day, which this year had the theme "Sustain Gains, Save Lives: Invest in Malaria."

27 Apr 2012

Smoking during pregnancy may increase risk of autism in children

Women who smoke in pregnancy may be more likely to have a child with high-functioning autism, such as Asperger's Disorder, according to preliminary findings from a study by researchers involved in the U.S. autism surveillance program of the Centers for Disease Control and Prevention.

27 Apr 2012

Longer looks: Why we still have faith in physicians

This patient is no fool, and she does't award trust liberally. … Yet, somehow, (Mary) Morse-Dwelley never lost faith in Pellegrini. She'd hear the click of her doctor's shoes in the hallway, see her blond hair and funky glasses, and feel confident that she was in good hands. This, too, represents a broad trend: As we have become better-informed patients, we have grown more cynical about a health care system that is ever more corporate and reliant on technology.

27 Apr 2012

Researchers discover small molecules that kill HPV-infected cancer cells

Researchers at The Wistar Institute announce the discovery of small molecules that kill cancer cells caused by infection with human papillomavirus (HPV). Their results, in both cell and mouse models, demonstrate that the small molecule inhibitors protect a tumor-suppressing protein targeted by viral proteins, thus killing the infected tumor cells.

27 Apr 2012

Global food prices increase in first quarter of 2012, World Bank report says

"Global food prices again rose in the first quarter of 2012 on the back of higher oil prices, putting millions of people at risk of not having enough to eat," according to a report released Wednesday by the World Bank, Agence France-Presse reports.

27 Apr 2012

Kras gene triggers metabolic changes that fuel cancer cells

Researchers at Dana-Farber Cancer Institute have shown that advanced pancreatic cancers in mice can't survive without continued expression of a mutant oncogene that "rewires" key metabolic pathways to fuel the cancer cells.

27 Apr 2012

Mass. cost control legislation advances to Senate committee

The measure, more than a year old, was initially put forth by Gov. Deval Patrick but the panel's chair predicted "a significant redraft" before it reaches the Senate flooor.

27 Apr 2012

Home-based dialysis more popular in developing countries

Researchers at Lawson Health Research Institute have discovered that developing countries have faster growing rates of use of home-based dialysis (called peritoneal dialysis) for kidney failure than the developed world. Despite home-based dialysis' reduced cost and better outcomes, developed countries (including Canada) are using this form of therapy less.

27 Apr 2012

House GOP eyes prevention trust fund as means to pay for student loan plan

House Speaker John Boehner, R-Ohio, has scheduled a Friday vote on the proposal, which some news outlets describe as a "bitter pill" for Democrats.

27 Apr 2012

New system assesses and records mobility of bedridden patients

Healthy people move an average of two to four times per hour in their sleep. The movements are triggered by pain that occurs when tissue has an insufficient blood supply. The sleeping person changes position involuntarily, relieves the pressure point and therefore prevents bedsores, which are known in professional jargon as "decubitus ulcers".

27 Apr 2012

Shutdown looms as committees, lawmakers spar over budget, spending cuts

The House Energy and Commerce Commitee, as well as other House panels, worked yesterday on various spending cuts and policy items with an eye on budget reconciliation. The GOP-led effort, which has very little chance of being taken up by the Senate, will likely lead to "a long summer of political skirmishing."

27 Apr 2012

Study explores resilin-like materials for vocal fold disorders

A one-inch long grasshopper can leap a distance of about 20 inches. Cicadas can produce sound at about the same frequency as radio waves. Fleas measuring only millimeters can jump an astonishing 100 times their height in microseconds. How do they do it? They make use of a naturally occurring protein called resilin.

27 Apr 2012

Smarter purchasing of bednets could save $630M over 5 years, report suggests

"A new report from the Results for Development Institute," released to coincide with World Malaria Day on Wednesday, "suggests there are ways to save and reinvest badly needed funds, by getting better value for money out of the bednets distributed in endemic areas," Guardian Health Editor Sarah Boseley reports in her "Global Health Blog."

27 Apr 2012

Rochester researcher to continue MS study

A Rochester, New York, researcher will receive a $263,622 grant to continue his study of injury to brain cell connections (synapses) in multiple sclerosis (MS) through the American Brain Foundation (formerly the American Academy of Neurology Foundation) and the National Multiple Sclerosis Society Clinician-Scientist Development Award.

27 Apr 2012

U.S. government 'catalyzing' international community to end preventable child deaths

"When it comes to promoting global health, the American people have much to celebrate and be proud of. With strong bipartisan support, the U.S. government has not only committed many billions of dollars and saved many millions of lives, it has changed the way the world approaches foreign aid," former U.S. Global AIDS Coordinator Ambassador Mark Dybul writes in an opinion piece in The Hill.

27 Apr 2012

USDA: Dairy cow in California tested positive for atypical BSE

This week, the U.S. Department of Agriculture (USDA) confirmed that a dairy cow in California tested positive for atypical bovine spongiform encephalopathy. The USDA also confirmed the cow did not enter the animal feed or human food supply

27 Apr 2012

Kenyan AIDS activists protest over unspent PEPFAR funds

"More than 400 Kenyan AIDS activists have demonstrated in the capital, Nairobi, demanding that the U.S. President's Emergency Plan for AIDS Relief release some $500 million for HIV programs in Kenya that is stuck in the pipeline," PlusNews reports.

27 Apr 2012

Hemodiafiltration does not improve kidney failure patients' survival or heart health

A technique that removes additional toxins during dialysis does not improve kidney failure patients' survival or heart health, but intense treatments may provide a benefit, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology.

27 Apr 2012