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FDA issues Complete Response Letter to Amgen’s sBLA for XGEVA

Amgen today announced that the U.S. Food and Drug Administration (FDA) has issued a Complete Response Letter for the supplemental Biologics License Application (sBLA) for XGEVA (denosumab) to treat men with castration-resistant prostate cancer (CRPC) at high risk of developing bone metastases.

27 Apr 2012

Poverty linked to HIV infection among heterosexuals living in inner-city neighborhoods

In a groundbreaking study published last year, scientists reported that effective treatment with HIV medications not only restores health and prolongs life in many HIV-infected patients, but also curtails transmission to sexual partners up to ninety-seven percent. However, a new study by UCSF scientists shows that lack of basic living needs severely undercuts these advances in impoverished men.

27 Apr 2012

Consumption of resistant starch leads to positive changes in the bowel

Consumption of resistant starch leads to positive changes in the bowel and could protect against genetic damage implicated in bowel cancer.

27 Apr 2012

UCSF researcher to study risk factors and consequences of stroke

A San Francisco researcher is receiving $130,000 for her research studying risk factors and consequences of stroke among different racial/ethnic groups through the AHA/ASA/ABF Lawrence M. Brass, MD, Stroke Research Postdoctoral Fellowship from the American Brain Foundation,(formerly the American Academy of Neurology Foundation), the American Heart Association and the American Stroke Association.

27 Apr 2012

Gamma and delta-tocopherols do prevent many cancers

Next time you need to choose between vegetable oil and margarine in that favorite recipe, think about your health and reach for the oil. While the question of whether vitamin E prevents or promotes cancer has been widely debated in scientific journals and in the news media, scientists at the Center for Cancer Prevention Research, at Rutgers Mario School of Pharmacy, and the Cancer Institute of New Jersey, believe that two forms of vitamin E - gamma and delta-tocopherols - found in soybean, canola and corn oils as well as nuts do prevent colon, lung, breast and prostate cancers.

27 Apr 2012

Share 35 policy reduces racial disparities in kidney transplantation among children

A policy instituted in 2005 has reduced racial disparities in kidney transplantation among children, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology.

27 Apr 2012

Healthy emmetropic women have a wider pupil diameter than men

From an anatomical point of view, a normal, non-pathological eye is known as an emmetropic eye, and has been studied very little until now in comparison with myopic and hypermetropic eyes. The results show that healthy emmetropic women have a wider pupil diameter than men.

27 Apr 2012

Low-intensity workout may be effective in building muscle

Weight training at a lower intensity but with more repetitions may be as effective for building muscle as lifting heavy weights says a new opinion piece in Applied Physiology, Nutrition, and Metabolism.

27 Apr 2012

GSK receives FDA approval for Votrient to treat advanced soft tissue sarcoma

The U.S. Food and Drug Administration today approved Votrient (pazopanib) to treat patients with advanced soft tissue sarcoma who have previously received chemotherapy. Soft tissue sarcoma is a cancer that begins in the muscle, fat, fibrous tissue, and other tissues.

27 Apr 2012

UIC researcher to explore causes of myasthenia gravis

A University of Illinois at Chicago researcher is the recipient of a $240,000 research grant to further explore the causes of myasthenia gravis, a neurologic disease affecting muscles.

27 Apr 2012

Diseases of the Colon & Rectum app now available for the iPad

Essential research and the latest commentary from the field of colorectal surgery is now available in a digital format with the availability of Diseases of the Colon & Rectum (DC&R) app for the iPad edition.

27 Apr 2012

New article describes design and properties of magnetoelectric composite materials

Up to now, the brain's magnetic field is measurable only under technical laboratory conditions. This technique is therefore not feasible in terms of the broader medical use, although it would be significant for diagnosing numerous conditions such as epilepsy and dementia, or even for improving therapies such as deep brain stimulation for treating Parkinson's disease.

27 Apr 2012

Positive top-line results from Shire’s Vyvanse Phase 2 study on binge eating disorder

Shire plc, the global specialty biopharmaceutical company, today announced positive top-line results from a Phase 2 study to evaluate the safety and efficacy of Vyvanse (lisdexamfetamine dimesylate) Capsules, (CII) in adults with binge eating disorder.

27 Apr 2012

Watson enters definitive agreement to acquire Actavis

Watson Pharmaceuticals, Inc. and Actavis Group today jointly announced that Watson has entered into a definitive agreement to acquire privately held Actavis for approximately EUR4.25 billion upfront.

27 Apr 2012

Novartis receives FDA approval for Afinitor to treat renal angiomyolipomas caused by TSC

The U.S. Food and Drug Administration approved Afinitor (everolimus), the first drug approved specifically to treat non-cancerous kidney tumors (renal angiomyolipomas) not requiring immediate surgery in patients with tuberous sclerosis complex.

27 Apr 2012

Playing action videogames cause differences in brain activity

A team led by psychology professor Ian Spence at the University of Toronto reveals that playing an action videogame, even for a relatively short time, causes differences in brain activity and improvements in visual attention.

27 Apr 2012

Simple wrist sensor could gauge severity of epileptic seizures

In this week's issue of the journal Neurology, researchers at MIT and two Boston hospitals provide early evidence that a simple, unobtrusive wrist sensor could gauge the severity of epileptic seizures as accurately as electroencephalograms (EEGs) do - but without the ungainly scalp electrodes and electrical leads.

27 Apr 2012

Asahi Kasei acquires ZOLL

Asahi Kasei Corporation, Japan's leading diversified chemical manufacturer with businesses in the health care, chemicals & fibers, homes & construction materials, and electronics sectors, announced today the successful completion of its acquisition of ZOLL Medical Corporation, a major US manufacturer of medical devices for critical care, on April 26, 2012, US Eastern time.

27 Apr 2012

Political cartoon: 'No, Please, After You!'

Kaiser Health News provides a fresh take on health policy developments with "No, Please, After You!" by Chip Bok.

27 Apr 2012

Ghana rolls out vaccines against pneumonia and diarrhoea

Ghana has become the first African country to introduce pneumococcal and rotavirus vaccines at the same time, simultaneously tackling the leading causes of the world’s two biggest childhood killers – pneumonia and diarrhoea.

26 Apr 2012